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Anti-epileptic drugs
1
11
Pharmacology
Undergraduate 3
09/12/2013

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Cards

Term
phenytoin,carbamazepine, lamotrigine, lacosamide, valproate
Definition
Inhibit voltage gated sodium channels
Term
ethosuximide, lamotrigine, gabapentin, pregabalin,valproate
Definition
Inhibit voltage gated calcium channels (T-type)
Term
retigabine
Definition
Potassium channel opener
Term
levetiracetam
Definition
Bind to, and alter synaptic vesicle protein 2A (SV2A);
(action of binding may differ depending on type of transmitter stored or released)
Term
lacosamide
Definition
Collapsin-response mediator protein (CRMP-2),blocks neurotrophic factors;
Term
phenobarbital, topiramate, lamotrigine
Definition
Block AMPA postsynaptic receptors
Term
felbamate
Definition
Block post synaptic NMDA receptors
Term
tiagabine
Definition
Inhibit GABA transporters (GAT-1)
Term
vigabatrin
Definition
Inhibit GABA transaminase (GABA-T)
Term
benzodiazepines
Definition
Enhance GABAA receptor action
Term
no confirmed drug
Definition
Potentially enhance GABAB action
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