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Term
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Definition
H1 Receptor Antagonists, 1st Generation
+ sedation
In OTC “cold” drugs
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Term
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Definition
H1 Receptor Antagonists, 1st Generation
+++ sedation
Widely used; not in newborns
Not with ototoxic antibiotics
Used in motion sickness
PD
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Term
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Definition
H1 Receptor Antagonists, 1st Generation
motion sickness, vestibular disturbances
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Term
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Definition
H1 Receptor Antagonists, 1st Generation
cardiotoxic at high levels, esp with antimicrobials (lethal ventricular arrhythmias) |
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Definition
H1 Receptor Antagonist, 2nd generation
No sedation!
Lower risk of cardiac effects (it’s the active metabolite that is not toxic from terfenadine)
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Term
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Definition
H1 Receptor Antagonist, 2nd generation
No sedation
Longer action
No sign. Cardiac effects
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Term
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Definition
H1 Receptor Antagonist, 2nd generation
oral, long-acting antihistamine that is similar chemically to loratadine
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Term
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Definition
| H1 Receptor Antagonist, 2nd generation |
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Term
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Definition
Release Inhibitor
inhibit immunologically triggered degranulation (e.g., lung mast cells)
work only in prophylaxis!
nasal spray, eye drops
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Term
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Definition
Release Inhibitor
inhibit immunologically triggered degranulation (e.g., lung mast cells)
work only in prophylaxis!
nasal spray, eye drops
inhibition of degranulation (e.g., by cromolyn sodium) prevents effects of all=much more efficient!
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