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Ancillary Drugs in Anesthesia UPDATED
Pharm Assessment 7
33
Pharmacology
Graduate
10/06/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
Drugs for Sedation
Definition
Diazepam Lorazepam Promethazine Diphenhydramine
Term
Drugs for Rapid sequence intubation
Definition
Lidocaine Atropine
Term
Drug for Anaphylaxis
Definition
Methylprednisolone
Term
Drugs for Aspiration Pneumonitis
Definition

Bicitra and Polycitra - antacids

Metoclopramide - domapine antagoist

Term
Drugs for Nausea/Vomiting
Definition

Scopolamine

Metoclopramide

Term
Drugs for Anti-cholinergics
Definition
Atropine Glycopyrrolate Scopolamine
Term
Drugs for Cardiovascular support
Definition
Dopamine Phenylephrine
Term
What is the Typical Drug Sequence before surgery?
Definition
1. Pre-op visit and interview 2. Night before surgery - Benzodiazepine 3. 1-2 Hrs before surgery: -Benzodiazepine po -150mL water -Opioid - IM - analgesia -Scopolamine - IM - amnesia, sedation -Cimetidine -decrease Gastric fluid increase pH -Glycopyrrolate 4. Transfer to surgery - 8-10 more drugs
Term
What problems do NSAIDS pose for post surgery?
Definition
Post-surgical bleeding - decrease platelet aggregation Fracture healing - COX2 inhibitors inhibit ossification process
Term
What can be used to neutralize existing gastric contents?
Definition
Antacids Non-particulate best so doesn't stay in stomach
Term
What can be used to accelerate gastric emptying?
Definition
Metoclopramide
Term
What is the mechanism of Metoclopramide?
Definition
Central effects - dopamine antagonism Antagonized by anticholinergics and narcotics Alters bioavailability of oral drugs
Term
What drug can be used to treat reflex bradycardia?
Definition
Atropine - vagolytic effect
Term
What 3 drugs can be used to dry overproduction of secretions?
Definition
Scopolamine >> Atropine
Term
What Anticholinergic can be used for sedation and amnesia preoperatively?
Definition
Scopolamine
Term
What is Rapid Sequence Intubation?
Definition
Process of Oxygenating the patient before administering anesthetics and intubating the patient
Term
What drug is used for increased intracranial pressure or penetrating injury, or reactive airway disease? (RSI)
Definition
Lidocaine
Term
Who might need Atropine to mitigate bradycardia in response to succinylcholine?
Definition
Children under 10yrs
Term
What is the most common reason for delayed awakening?
Definition
Residual anesthetics and ancillary drugs
Term
How is anaphylaxis managed?
Definition

Initial: Stop drug administration and anethesia

Give O2

Give Epinephrine and Fluids

 

Secondary: Antihistamines

Catecholamines

Corticosteroids

Sodium bicarbonate

Term
Diazepam
Definition

Sedation


Oral benzodiazepine

Given the night before or hours before surgery

Term
Lorazepam
Definition

Sedation


Oral or IM benzodiazepine

Given the night before or hours before surgery

Term
Promethazine
Definition

Sedation

 

Oral or IM 1st Generation Antihistamine

Risk of seizures

Bronchodilator

Sedative

Anti-anxiety

Anti-Emetic

Analgesic

Term
Diphenhydramine
Definition

Sedation

 

Oral or IM 1st Generation Antihistamine

Bronchodilator

Sedative

Anti-anxiety

Anti-Emetic

Analgesic

Term
Lidocaine
Definition

RSI

 

Topical anesthetic

Treat elevated intracranial pressure and reactive airway disease

Term
Atropine
Definition

RSI and Anti-cholinergic

 

Used in children under 10

Drying of secretions

Treat reflex bradycardia

Term
Bicitra
Definition

Aspiration

 

Antacid (Na + K-citrate)

Raise gastric pH (less acidic)

Liquid - less risk of aspiration

Term

Metoclopramide

 

Definition

Aspiration and Nausea/Vomiting

 

Dopamine antagonist

Accelerate gastric emptying

Causes sedation

Increased risk of seizure

Antagonized by anticholinergics and narcotis

Alters bioavailability of other drugs

 

Term
Scopolamine
Definition

Nausea / Vomiting and Anticholinergic

 

Cholinergic antagonist

Blocks pathway from inner ear

Cheapest

Sedation and amnesia

Vagolytic and antisialogogue

Term
Glycopyrrolate
Definition

Anti-Cholinergic

 

Drying of secretions (strongest)

Term
Dopamine
Definition

Cardiovascular support

 

Treat hypotension

Term
Phenylephrine
Definition

Cardiovascular support

 A1 Agonist

Treat hypotension

Term
Methyprednisolone
Definition

Anaphylaxis Management

 

Corticosteroid

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