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Anasthetics
Anasthetics top 20
155
Pharmacology
Graduate
02/18/2011

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Term
Generic name for Nimbex
Definition
Cisatracurium
Term
Generic name for Cytarabine
Definition
Cytarabine
Term
Generic name for Suprane
Definition
Desflurane
Term
Brand name for Cistracurium
Definition
Nimbex
Term
Brand name for Desflurane
Definition
Suprane
Term
Brand Name for Cytarabine
Definition
Cytarabine
Term
Generic name for Vepesid
Definition
Etoposide
Term
Brand name for Etoposide
Definition
Vepesid
Term
Generic name for Robinul
Definition
Glycopyrrolate
Term
Brand name for Glycopyrrolate
Definition
Robinul
Term
Generic name for Epifoam
Definition
Hydrocortisone Acetate and Pramoxine HCl
Term
Brand name for Hydrocortisone Acetate and Pramoxine HCl
Definition
Epifoam
Term
Generic name for Ifex
Definition
Ifosfamide
Term
Brand name for Ifosfamide
Definition
Ifex
Term
Generic name for Forane
Definition
Isoflurane
Term
Brand name for Isoflurane
Definition
Forane
Term
Generic name for Xylocaine
Definition
Lidocane
Term
Brand name for Lidocaine
Definition
Xylocaine
Term
Generic name for Brevital
Definition
Methohexital
Term
Brand name for Methohexital
Definition
Brevital
Term
Generic name for Papaverine
Definition
Papaverine
Term
Brand name for Papaverine
Definition
Papaverine
Term
Generic name for Diprivan
Definition
Propofol
Term
Brand name for Propofol
Definition
Diprivan
Term
Generic name for Naropin
Definition
Ropivacaine
Term
Brand name for Ropivacaine
Definition
Naropin
Term
Generic name for Ultane
Definition
Sevoflurane
Term
Brand name for Sevoflurane
Definition
Ultane
Term
Generic name for Hyalgan
Definition
Sodium Hyaluronate
Term
Brand name for Sodium Hyaluronate
Definition
Hyalgan
Term
Generic name for Acectine
Definition
Succinylcholine Chloride
Term
Brand name for Succinylcholine Chloride
Definition
Anectine
Term
Generic name for Thrombin-JMI
Definition
Thrombin
Term
Brand name for Thrombin
Definition
Thrombin-JMI
Term
Generic name for Norcuron
Definition
Vecuronium
Term
Brand name for Vecuronium
Definition
Norcuron
Term
Generic name for Oncovin
Definition
Vincristine Sulfate
Term
Brand name for Vincristine Sulfate
Definition
Oncovin
Term
Generic name for Zemuron
Definition
Rocuronium Bromide
Term
Brand name of Rocuronium Bromide
Definition
Zemuron
Term
Indication for Nimbex/Cistracurium
Definition
Neuromuscular blockade as adjunct to GA for tracheal intubation/mechanical vent
Term
Nimbex/Cisatracurium Strength, formulation and route
Definition
2mg/ml as 5 and 10ml vials for injection
Term
Nimbex/Cisatracurium dosing (initial and maintenance)
Definition
initial: 0.15-0.20mg/kg maintenance: 0.3mg/kg
Term
Nimbex/Cisatracurium drug inteactions
Definition
Aminoglycosides, tetracyclines, bacitracin, polymixins, lincomycin, clindamycin, colistin, Mg salts, litium, local anesthetics, procainamide, quinidine, colistemethate
Term
Nimbex/Cisatracurium Side effects
Definition
bradycardia, hypotension, flushing, bronchospasm, rash
Term
Cytarabine indication
Definition
acute non-lymphocytic leukemia and blast phase of chronic myelocytic leukemia
Term
How is Cytarabine supplied/form/route
Definition
100mg, 500mg, 1g, 2g vials for injection
Term
Dosing for Cytarabine
Definition
100mg/m2/day by continuous IV infusion or q12h
Term
Cytarabine drug interactions
Definition
Digoxin, cyclophospharmide, vincristine, prednisone, cytarabine, procarbazine
Term
Cytarabine side effects
Definition
anorexia, nausea, vomiting, diarrhea, hepatic dyfxn, fever rash, thromboflebitis
Term
Cytarabine box warning
Definition
Bone marrow suppression, leukopenia, thrombocytopenia, anemia. Oral ulceration, hypatic dysfxn
Term
Suprane indication
Definition
General anesthesia
Term
Suprane/Desflurane dosing
Definition
admin via vaporizer ONLY! Initial: 0.5-3% increasing by 0.5-1% every 2-3 breaths until onset of anesthesia
Term
Suprane/Desflurane side effects
Definition
hyperthermia, apnea, breath-holding, caoughing, excitement/struggling, increased secretion, laryngospasm, oxyhemoglobin desaturation, pharyngitis
Term
Suprane/Desflurane drug interactions
Definition
Aminoglycosides, bacitracin, capreomycin, citrate-anticoag blood, clingamycin, colistimethate, colistin, lidocaine, lincomysin, neuromuscular blocades, polymixins, procaine, tetracyclines, trimethaphan, amiodarone, antihypertensives, diuretics, antimyasthenics, betablockers
Term
Vepesid/Etoposide indication
Definition
Small cell cancer and refractory testicular tumors
Term
Vepesid/Etoposide supply/formulation/route
Definition
20mg/ml concentration for IV injection as 100/5,500/25,1gm/50ml multi-dose vials
Term
Vepesid/Etoposide dosing
Definition
Testicular CA: 50-100mg/m2/day for 5 days
Small cell lung CA: 35-50mg/m2/day for 5 days. Repeated on 3-4wk intervals
Term
Vepesid/Etoposide warnings
Definition
Mylosupression involving bone marrow (dose limiting)
Term
Vepesid/Etoposide side effects
Definition
Hypotension
Term
Robinul/Glycopyrrolate indication
Definition
Peptic ulcer
Term
Robinul/Glycopyrrolate supply/form/route
Definition
1mg and 2mg tablets via oral route
Term
Robinul/Glycopyrrolate dosing
Definition
Varies from patient to patient. Max daily dose of 8mg
Term
Robinul/Glycopyrrolate contraindications
Definition
Glaucoma, obstructive uropathy, atony of the elderly, unstable cardiovascular, myesthenia gravis and ulcerative colitis
Term
Robinul/Glycopyrrolate warning
Definition
avoid with high temperature, stroke can occure.
Term
Robinul/Glycopyrrolate side effects
Definition
CNS effects: drowsiness, neuromuscular blockade, muscular weakness, paralysis
Term
Epifoam/Hydrocortisone with Pramoxine indication
Definition
hemorrhoids, anal fissures, dermatitis, psoriasis
Term
Epifoam/Hydrocortisone with Pramoxine supply/formulation/route
Definition
10g pressurized aerosol topical foam 1%-hyrdocortisone 1%-pramoxine
Term
Epifoam/Hydrocortisone with Pramoxine dosing
Definition
Apply to affected are TID-QID
Term
Epifoam/Hydrocortisone with Pramoxine side effects
Definition
Burning, itching, irritation, dryness, folliculitis, hypertrichosis, acne, hypopigmentation, perioral dermatitis, allergic dermatitis, maceration of skin, secondary infxn, skin atrophy, striae, millaria
Term
Ifex/Ifosamide indication
Definition
3rd line for germ cell testicular cancer
Term
Ifex/Ifosfamide supply/formulation/route
Definition
1g and 3g single dose vials for injection
Term
Ifex/Ifosfamide dosing
Definition
1.2g/m2/day for 5 days. Repeat q3wk
Term
Ifex/Ifosfamide contraindications
Definition
Patients with severely depressed bone marrow fxn
Term
Ifex/Ifosfamide side effects
Definition
Alopecia (83%), N/V, hematuria, CNS toxicity, infxn
Term
Ifex/Ifosfamide box warning
Definition
Urotoxic side effects (Hemorrhagic cystitis) and CNS toxicity such as coma
Term
Xylocaine/Lidocane indication
Definition
Local or regional anesthesia
Term
Xylocaine/Lidocane supply/formulation/route
Definition
0.5% (5mg/ml)as 50ml
1% (10mg/ml) as 2,3,40ml vials
1.5% (15mg/ml) as 20ml vial
2% (20mg/ml) as 2, 5, 10ml vials
4% (40mg/ml) as 5ml vial for injection
Term
Xylocaine/Lidocane dosing
Definition
For IV only use 0.5% 50ml SDV max dose of 4.5mg/kg/dose Do not exceed 300mg
Term
Xylocaine/Lidocane contraindication
Definition
Hypersensitivity to amide local anesthetics
Term
Xylocaine/Lidocane drug interactions
Definition
MAOI, tricyclic antidepressants, phenothiazines, butyrophenones
Term
Xylocaine/Lidocane side effects
Definition
Drowsiness, dizziness, euphoria, confusion, resp depression, blurred/double vision, vomiting
Term
Brevital/Methohexital indications
Definition
Induction of general anesthetic
Term
Brevital/Methohexital supply/formulation/route
Definition
500mg/50ml vial, 2.5g/50ml vial for injection
Term
Brevital/Methohexital dose
Definition
Induction: 1-1.5mg/kg IV
Maint: about 20-40mg q4-7min
Term
Brevital/Methohexital contraintications
Definition
Latent/manifest porphyria, barbiturate hypersensitivety
Term
Brevital/Methohexital drug interactions
Definition
Phenytoin, halothane, anticoagulants, corticosteroids, ethyl alcohol, propylene glycol containing solutions
Term
Brevital/Methohexital side effects
Definition
hypotension, tachycardia, respiratory depression, nausea, abd pain
Term
Papaverine indication
Definition
Cerebral and peripheral ischemia from arterial spasm
Myocardial ischemia w/ arrythmia
Erectile dyfxn w/ or w/o phentolamine
Acute vascular occlusion w/ anticoag
Term
Papaverine supply/formulation/route
Definition
150mg ER cap
30mg/ml MDV or preservative free as SDV
Term
Papaverine dose: Cardio/vascular, ED, Oral
Definition
C/V: 30mg IV or IM every 3 hours
ED: 2.4-37.5mg Intracavernosal
PO: 150mg q8-12h or 300mg q12h
Term
Papaverine contraindications
Definition
AV heart block
Term
Papaverine drug interactions
Definition
CNS depressants, levodopa, morphine
Term
Papaverine side effects
Definition
N/D/C, tachycardia, anorexia, abd distress, malaise, drowsiness, vertigoo, sweating, HA, rash, flushing,sedation, hepatitis, hypo/hypertension, thrombosis @ inj site
Intracavernosal: priapism, pain, burning, paresthesia
Term
Diprivan/Propofol indication
Definition
Induction and maintenance of anesthesia
Term
Diprivan/Propofol supply/formulation/route
Definition
10mg/ml concentration in 10, 50, 100ml vial for infusion
Term
Diprivan/Propofol dosing
Definition
Individualized
Begin at 0.3mg/kg/hr inc by 0.3-0.6mg/kg/hr until desired sedation
Maint: 0.3-3mg/kg/hr (5-50ug/kg/min)
Term
Diprivan/Propofol drug interactions
Definition
Morphine, meperidine, fentanyl, benzos, barbiturates,chloral hydrate, droperidol, opioids, nitrous oxide
Term
Diprivan/Propofol side effects
Definition
Brady/tachycardia, arrythmia, hypotension, burning at inj site, apnea, rash, puritis
Term
Naropin/Ropivacaine indication
Definition
Epidural block for surgery, cesarean, acute pain, labor
Term
Naropin/Ropivacaine supply/formulation/route
Definition
2,5,7.5,10mg/ml for injection
Term
Naropin/Ropivacaine dosing
Definition
Surgical:5-10mg/ml
Labor: 2mg/ml
Post-op: 2-5mg/ml
Max 770mg/24h
Term
Naropin/Ropivavaine contraindications
Definition
Hypersensitivity to amide anesthetics
Term
Naropin/Ropivacaine drug interactions
Definition
Fluvoxamine, amiodarone, ibutilide, sotalol, dofetilide, dronedarone, and CYP1A2 inhibitors
Term
Naropin/Ropivacaine side effects
Definition
N/V, hypotension, bradycardia, HA, paresthesia, pain, puritis, fever, chills, DZ, hypoesthesia, urinary retention, failed progression of labor, anxiety, rhinitis
Term
Anectine/Succinylcholine indication
Definition
Neuromuscular blockade and aid in intubation (ultra short acting skeletal muscle relaxant)
Term
Anectine/Succinylcholine supply/formulation/route
Definition
20mg/ml concentration in 10ml vials for IV injection
Term
Anectine/succinylcholine dose
Definition
Short procedure: 0.6mg/kg
Long procedure: 2.5-4.3mg/min
Term
Anectine/Succinylcholine contraindications
Definition
malignant hyperthermia, skeletal muscle myopathies, acute phase of injury (burns, trauma, skeletal muscle, neuron)
Term
Anectine/Succinylcholine drug interactions
Definition
promazine, oxytocin, aprotinin, quinidine, beta blockers, procainamide, lidocain, trimethaphan, lithium, Mg salts, quinine, chloroquine, diethylether, isoflurane, desflurane, metoclopramide, terbutaline
Term
Anectine/Succinylcholine side effects
Definition
Cardiac arrest, malignant hyperthermia, arrythmia, brady/tachycardia, hyper/hypotension, hyperkalemia, resp depression/apnea
Term
Anectine/Succinylcholine box warning
Definition
Risk of cardiac arrest from hyperkalemic rhabdomyolysis
Term
Thrombin supply/formulation/dose
Definition
5,000IU; 20,000IU; Vial
20,000IU nasal spray
20,000IU syringe kit
5,000IU epistaxis kit
Term
Thrombin indication
Definition
hemostasis w/ minor bleeding from capillaries and small venules
Term
Thrombin dose
Definition
apply 1,000-2,000IU/ml solution to area of bleed
Percutaneous: 100-1000IU/ml 0.3-3ml
Term
Thrombin contraindications
Definition
Bovine derivatives
Term
Thrombin box warning
Definition
Altered PT (prothrombin time)and PTT (partial thromboplastin time), severe bleeding
Term
Norcuron/Vecuronium indication
Definition
adjunct to GA. Neuromuscular block, tracheal intubation
Term
Norcuron/Vecuronium supply/formulation/route
Definition
10 and 20mg for IV
Term
Norcuron/Vecuronium dose
Definition
0.08-0.1mg/kg IV bolus
Term
Norcuron/Vecuronium drug interactions
Definition
succinylcholine, inhaled anesthetics, aminoglycosides, tetracyclines, bacitracin, tiopental
Term
Norcuron/Vecuronium side effects
Definition
Drug action longer than needed causing weakness, prolonged muscle paralysis, resp insufficiency, apnea
Term
Oncovin/Vincristine indication
Definition
Leukemia or in combo therapy for Hodgkins, Non-Hodgekins, rhabdomyosarcoma, neuroblastoma, Wilms tumor
Term
Oncovin/Vincristine supply/formulation/route
Definition
1mg/ml concentration as 1 and 2ml vials *keep refridgerated and protect from light
Term
Oncovin/Vincristine dose
Definition
1.4mg/m2
Term
Oncovin/Vincristine contraindications
Definition
Demyelinating Charot-Marie-Tooth syndrome
Term
Oncovin/Vincristine drug interactions
Definition
Do not mix w/ solutions that change pH outside range of 3.5-5.5
Do not mix with anything other than NS or glucose in water
Term
Oncovin/Vincristine side effects
Definition
Neuromuscular: loss of tendon relfex, foot drop, ataxia, paralysis, jaw pain, pharyngeal pain
GI: constipation, abd cramp, wt loss
Genitourinary: polyuria, dysuria, urinary retention
Cardio: hyper/hypotension
Fever and HA
Term
Oncovin/Vincristine box warning
Definition
Fatal if given intrathecially, Extravasion must DC dose and inject remainder in another vein
Cellulitis
Term
Zemuron/Rocuronium indication
Definition
Adjunct to GA for intubation/mechanical vent
Term
Zemuron/Rocuronium supply/form/dose
Definition
10mg/ml concentration as 50mg/5ml or 100mg/10ml MDV for injection
Term
Zemuron/Rocuronium dose
Definition
Induction: 0.6-1.2mg/kg
Maint: 10-12mcg/kg/min
Term
Zemuron/Rocuronium drug interactions
Definition
Anasthetics, aminoglycosides, vancomycin, tetracyclines, bacitracin, polymixins, colistin, colistimethate, quinidine, Mg, lithium, procainamide cause ENHANCED Zemuron
Anticonvulsants cause DECREASED Zemuron
Term
Chemo drugs
Definition
Cytarabine, Vepesid/Etoposide, Ifex/Ifosfamide, Oncovin/Vincristine
Term
Drugs indicated for testicular cancer
Definition
Vepesid/Etoposide and Ifex/Ifosfamide
Term
Indicated for GA
Definition
Suprane/Desflurane
Term
Indicated for intubation
Definition
Nimbex, Anectine, Norcuron, Zemuron
Term
Indicated for induction of GA
Definition
Forane, Brevital, Diprovan, Ultane
Term
Which drugs do not have any drug interactions
Definition
Vepesid, Robinul, Epifoam, Ifex, Thrombin
Term
Generic name for Ultane
Definition
Sevoflurane
Term
Brand name for Sevoflurane
Definition
Ultane
Term
Indication for Ultane/Sevoflurane
Definition
Induction/maint of GA
Term
Ultane/Sevoflurane strength/formulation/route
Definition
250ml vials of volatile sevoflurane for ihalation
Term
Ultane/Sevoflurane dosing
Definition
individualized for pt depending on respsone, delivered via vaporizer
Term
Ultane/Sevoflurane contraindications
Definition
susceptibility to malignant hyperthermia or halogenated hypersensitivity
Term
Ultane/Sevoflurane drug interactions
Definition
Compatible w/ IV anesthetics!
Nitrous oxide interation, neuromuscular blockade interaction (pancuronium, vecuronium, atracurium)
Term
Ultane/Sevoflurane side effects
Definition
Brady/tachycardia, hypotension, laryngospasm, airway obstruction, cough, breath holding, seizures
Term
Generic name for Hyalgan
Definition
Sodium Hyaluronate
Term
Brand name for Sodium Hyaluronate
Definition
Hyalgan
Term
Indication for Hyalgan/Sodium Hyaluronate
Definition
Osteoartheritis for pt failing non-pharmacologic therapy and APAP
Term
Hyalgan/Sodium Hyaluronate Strength/Formulation/Route
Definition
20mg/2ml vial or prefilled syringe for intra-articular injection
Term
Hyalgan/Sodium Hyaluronate dose
Definition
5 2ml inj/wk
Term
Hyalgan/Sodium Hyaluronate contraindications
Definition
injection site/sking infection/disease
Term
Hyalgan/Sodium Hyaluronate drug interactions
Definition
Disinfectants w/ quaternary ammonium salts
Term
Hyalgan/Sodium Hyaluronate side effects
Definition
GI, inj site pain, swelling/effusion, local rxn (rash etc), puritus, HA
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