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Alteration in Immune Responce
Test 1
8
Pathology
Undergraduate 1
01/25/2013

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Cards

Term
Excessive and/or inappropriate activation of the immune responce
Definition
Hypersensity/ AutoImmune
Term
Types of Hypersensitivity reactions
Definition
  • 1- Allergic/ Anaphylatic
  • 2- Antibody mediated
  • 3- immunne-complex mediated
  • 4- Tcell mediated
Term
This is an allergic, has to do with mast cells
Definition
type 1
Term
What happens druing type 1 reaction
Definition
  • Mast cell exsposed to antigen
  • IGE made
  • IGE attach to mast cell
  • Second exsposure antigen attaches on mast cell causing degranulation
Term
What happens during mast cell degranulation?
Definition
Vasodilation, Bronchoconstriction, vascular permeabitiy, itiching exx
Term
What does Arachidonic acid create?
Definition
Prostaglandin and Leukotriens
Term
This is a systemic responce to the inflammatory mediators released in Type 1 reactions
Definition
Anaphylaxis
Term
This happens when failure to reconize self, immune system attacks body and destroys tissue.
Definition
Autoimmune disease type 2,3,4
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