Term
| What is the best initial therapy for Anaphilaxis? |
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Definition
Epinephrine
antihistamines (diphenhydramine H1blocker)(Ranitidine H2 blocker)
Glucocorticoids
Emergent airway protection if needed |
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Term
what is angio edema?
What is the difference between Hereditary angioedema? |
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Definition
Sudden sweelling of the face/airways
Hereditary has absence of pruritus/urticaria and
Does not respond to glucocorticoids |
|
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Term
what is the BITest for Angioedema?
What is the acute therapy x3
What is the long term therapy? |
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Definition
decreased levels of C2 and C4 and C1 esterase inhibitor deficiency.
Airway protection, fresh frozen plasma or ecallantide
Androgens: danazol, stanazol |
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Term
What is the treatment for Urticaria?
What drug can cause Angioedema? |
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Definition
Antihistamines
Leukitrien receptor antagonist: montelukast, zafirlukast
----------------
ACEi |
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Term
Name 3 big Fist generation Antihistamines (generic and trade name)
What are side effects (3 classes) |
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Definition
Diphenhydramine- Benadril/ Sominex
Promethazine - Phenagrin
Meclizine- Dramamine
M-block: Drymouth, blurred vision
Sedation, and Antimotionsickness |
|
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Term
Name 3 big Second Generation Antihistamines (Generic and Trade names)
What are the difference btw Second and first gen antihistamines? |
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Definition
Citirizine- Zyrtec
Loratadine- Claritin
Fexofenadine- Allegra
+/- antiM: Dry mouth/blurred vision
No Sedation or Antimotionsickness |
|
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Term
what is the Presentation for Common variable Immunodef?
Diagnostic Test?
Treatment? |
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Definition
recurrent sinopulm infections in adults
Dx: decreased Immunoglobulin levels, decreased response antigen stim of Bcells
Treat infections and Immunoglobine injections |
|
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Term
What is the treatment for Brutons agammaglobulinemia?
What does Common Variable Immunodef give a higher risk of? |
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Definition
treat infections and long term admin of IVIG (IV immunoglob)
Lymphoma |
|
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Term
What is the Treatment for SCID?
What is the Presentation for IgA Def?
What is the treatment for IgA def? |
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Definition
Treat infections, Bone marrow transplant is curative.
Recurrent sinopulmonary infections
treat infections, Only use blood from IgA def donors due to antigens;
IVIG does not work |
|
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Term
What does Hyper IgE syndrome present with?
what does Wiskott-aldrich syndrome Present with
what is the treatment? |
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Definition
Immunodef, thrombocytopenia, eczema
Bone marrow transplant is the only definitive treatment? |
|
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Term
What is the guidelines for Mammography?
What drug is most likely to benefit pt with multiple 1st degree relatives with breast cancer? |
|
Definition
controversial: start 40-50 every 2 years Screening can stop at 75.
SERMs: Tamoxifen and raloxifene |
|
|
Term
In breast cancer when is ----useful?
SERMS? what are the drugs?
Aromatase Inhibitors? what is the main drug
Transtuzumab
Chemo?
|
|
Definition
SERMS: Tamoxifen and raloxifene
1.Post Dx ER/PR testing +
2.Prophilaxis of high risk
Aromatase Inhibitors -Anasterol
Prevention of mets/ Most likley to benifit
Transtuzumab- Post dx Her2/neu + |
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Term
| What are the guidelines for Cervical cancer screenings and Pap Virus? |
|
Definition
1. from the ages of 21-65
2. every 3 years
3. Pap Vaccine given (11-26yo)
4. Combo Pap + HIV test extends 30-65 to every 5 years |
|
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Term
What are the guidelines for Colonoscopy?
For Prostate Screenings?
For lung Cancer? |
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Definition
Every 10 years after 50
There is no clear mortality benefit for Prostate Screenings (PSA or DRE) it is always the wrong answer for screeningsz) on the exam.
No screening for lung cancer |
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Term
| When are Cholesterol and LDL measurments recommended? |
|
Definition
Men above 35
Women above 45
All Pt with: DM, HTN, CAD, PVD |
|
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Term
What are the guidelines for -- Screening?
HTN
Osteoporosis
-with what
-if Positive |
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Definition
HTN: >18 every time in office or every 2 years
Ost: All woman >65
Bone densitometry (DEXA scan)
Give give Bisphosophonates |
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Term
Who should be asked about intimate partner Violence?
What are the CAGE questions |
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Definition
All pts
Cut down, Angery at others, guilty, Eye opener |
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Term
| When should Diabetic Screenings happen? |
|
Definition
No clear recomendations for general public
done when patients have HTN and Hyperlipidemia |
|
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Term
When should the tetanus toxin varients be given (x3)
|
|
Definition
Never vaccinated: Td(toxoid) every ten years
Dirty wound: Tdap booster after 5 years
Clean wound: Booster after 10 years
Tetanus Immune globulin:1.wound with <3 doses of Td
Dirty wound >10yrs sence Td |
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