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Allergic Rhinitis & Colds Background & Treatment
Allergic Rhinitis & Colds Background & Treatment
47
Pharmacology
Professional
08/29/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
Allergic rhinits is also known as?
Definition
Hay fever
Term
What is rhinitis?
Definition
an inflammation of the membrane linings in the nose.
Term
What are some non-pharmacologic management of rhinitis?
Definition

environmental control (avoiding exposure to allergens)

 

Neti Pots

 

Not overly sanitizing infants is important: children need to build a healthy immune system and over - worry about cleanliness ends up causing more illness.

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Term
What is first line for moderate - to - severe rhinits?
Definition

Intranasal corticosteroids

 

Milder, intermittent symptoms can be treated with oral antihistamines.

Term
brand name for flucticasone furoate
Definition
Veramyst
Term
Brand name for Fluticasone propionate
Definition
Flonase
Term
Brand name for Mometasone
Definition
Nasonex
Term
Brand name for Triamcinolone
Definition
Nasacort AQ
Term
[image]
Definition
Statement. Not a question.
Term
Oral antihistamines are considered what line and for what condition?
Definition

first line for patients with mild - moderate disease

Term
oral antihistamines are effective in reducing symptoms of...
Definition

itching, sneezing, and rhinorrhea. They have little effect on nasal congestion

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Term
Are oral antihistamines helpful for allergic conjunctivitis
Definition
may help iwth allergic conjunctivitis
Term
MOA of oral antihistamines
Definition
antagonists of histamine at the H1 receptor site; competitive binding
Term
Side effects of second - generation antihistamine agents
Definition

second - generation agents have less side effect, including less sedation

 

Term
Brand name for Diphenhydramine
Definition
Benadryl
Term
Brand name for Certirizine
Definition
Zyrtec
Term
Brand name for Desloratadine
Definition
Clarinex
Term
Brand name for Fexofenadine
Definition
Allegra D12H, D24H
Term
Brand name for Levocetirizine
Definition
Xyzal
Term
Brand name for Loratadine
Definition
Claritin, Claritin-D 24 hour, Claritin RediTabs, Alavert
Term
Brand name for Azelastine
Definition
Astelin
Term
[image]
Definition
Statement. Not a question.
Term
Decongestants are effective in?
Definition
reducing nasal congestion
Term
MOA of decongestants
Definition

alpha adrenergic agonists that cause nala vasoconstriction

[image][image][image][image]Wikipedia: agonist definition: one that is engaged in a struggle.

Term
Side effects and caution when using decongestants
Definition

 

Side effects include insomnia, loss of appetite, excessive nervousness, increased BP, paplitations

 

Caution in certain conditions: arrhytmias, angina pectoris, patients with HTN, CAD, hyperthroidism, glaucoma, diabetes, urinary dysfunction &c.

 

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Term
[image]
Definition
Statement. Not a question.
Term
Name oral decogestants
Definition

(1) Pseudoephedrine (Sudafed) - 30 mg Q 12 hours

 

(2) Phenylephrine (Sudfed PE) - not as effective as pseudoephedrine 5 mg, 1-2 Q 4-6 hours, max 8/day

Term
Name topical decogestants
Definition

Naphazoline

Phenylephrine

Oxymetazoline

Tetrahydrozoline

Xylometazoline

 

Term
How long should topical decogestants be used?
Definition

For topical agents, limit use to < 5 days (ideally 2-3 days) to prevent rebound congestion, or rhinitis medicamentosa ---> usually occurs after 5 - 10 days of treatment.

Term

Brand name for Intranasal cromolyn

 

Definition

Nasalcrom

 

Term
Is Nasalcrom effective?
Definition

(A) Takes 4-7 days to see symptom relief; up to 2 weeks for maximal effect

(B) Not as effective as other agents

(C) Due to its safety prfile, consider for young children and pregnany

[image][image][image][image]

Term
Brand name for ipratropium bromide
Definition
Atrovent Nasal Spray
Term
ipratropium bromide effectiveness?
Definition

Effective in reducing rhinorrhea but no effect on other nasal symptoms (can cause nasal dryness)

 

Usually used in combination with other agents when rhinorrhea is the predominant symptom

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Term
Name an oral antileukotriene
Definition
Montelukast
Term
Brand name for Monetlukast
Definition
Singulair
Term
Effectiveness of Montelukast
Definition

Not any more effective than antihistamines or pseudoephedrine

Term
What is a neti pot?
Definition

A neti pot looks like a small genie lamp or teapot. It is used to hold salt water (saline solution) that is poured into one nostril and allowed to drain out the other nostril. This technique may help with sinus symptoms. It can clear out your nasal passages, reduce swelling. Neti pots are safe for children and pregnant women. The most common side effects are burning or stinging in the nose.

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Term
How young should OTC cough and cold products be used in children?
Definition

OTC cough and cold products should NOT be used in children under age 4.

Term
Treatment for children with colds
Definition

recommend nasal bulbs for gentle suctioning, saline drops/sprays (Ocean and generics) and tell parents that the medications have not been shown to work in young children, they can be dangerous, and symptoms usually resolve in a few days or up to 2 weeks.

Term
What OTC pain relievers can be used in children?
Definition
ibuprofen and acetaminophen
Term

Children:

[image]

 

Definition
Statement. Not a question.
Term
[image]
Definition
Statement. Not a question.
Term

When to prime your bottle of VERAMYST Nasal Spray?

Definition

You need to prime your bottle of VERAMYST Nasal Spray before using it for the first time, not every time.

Term
When to reprime VERAMYST Nasal Spray?
Definition

You ONLY need to reprime your bottle of VERAMYST Nasal Spray if:

 

(1) Device has not been used for 30 days or more

(2) Cap has been lfet off the bottle for 5 days or longer

Term
[image]
Definition
Statement. Not a question.
Term

[image]

See the flip for the "Don't"

Definition
[image]
Term
[image]
Definition
Statement. Not a question.
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