Term
| 6 consequences of polymorphic drug interactions |
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Definition
| no activation, less effect, extended effect, dose alterations, drug-drug interactions, adverse drug interactions |
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|
Term
| 6 types of drug interactions |
|
Definition
| pharmacodynamics, inhibition, induction, excretion, chemical, displacement |
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Term
| sucralfate, milk products, antacids, and iron inhibit the absorption of... |
|
Definition
| tetracycline, quinolones, and azithromycin |
|
|
Term
| what inhibits absorption of ketoconazole? |
|
Definition
|
|
Term
| what inhibits absorption of raloxifene, digoxin, and thyroxine? |
|
Definition
|
|
Term
|
Definition
| -azoles, grapefruit juice, SSRIs, macrolides |
|
|
Term
|
Definition
| phenobarbital, carbamazepine, St. John's wort, rifampin |
|
|
Term
| what increases risk of digitalis toxicity? |
|
Definition
| TZD diuretics, loop diuretics (hypokalemia) |
|
|
Term
| what increases risk for hyperkalemia and subsequent arrhythmias |
|
Definition
| K+ sparing drugs, ACEi, ARB, beta blockers |
|
|
Term
| what does hyponatremia increase the risk for? |
|
Definition
|
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Term
| effects of morphine on histamine, pCO2, amylase, ANP, and respirations |
|
Definition
| decreases respirations; increases histamine, pCO2, amylase, and ANP |
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|
Term
what deficiency is caused by...
1. MTX, TMP-SMX, or pyrimethamine
2. warfarin, cephalosporin
3. nitrous oxide
4. isoniazide
5. phenytoin |
|
Definition
1. folate deficiency
2. vitamin K
3. B12
4. B6
5. vitamin D |
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|
Term
| what 4 drugs increase warfarin effectiveness |
|
Definition
| NSAID, clopidogrel, thyroxine, gingko biloba |
|
|
Term
| SSRIs, TCAs, MAOIs, opioids, and atypical antipsychotics have the risk of causing... |
|
Definition
|
|
Term
| inhaled anesthetics, antidepressants, and MAOIs have the risk of causing... |
|
Definition
|
|
Term
| antidepressants, antipsychotics, macrolides, and quinolones have the risk of causing... |
|
Definition
| long QT syndrome (tx with Mg) |
|
|
Term
| genetic testing should be done for what 2 drugs? |
|
Definition
|
|
Term
| cholestyramine inhibits absorption of what 3 drugs? |
|
Definition
| raloxifene, digoxin, thyroxine |
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