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Acute Coronary Syndrome Myocardial Infarction
pharmcotherapy spring 2014
21
Pharmacology
Professional
01/13/2014

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Cards

Term
MONA
Definition
morphine, oxygen, nitroglycerine, and aspirin
Term
intervenous
Definition
metoprolol, morphine,
Term
oral
Definition
aspirin, clopidogrel, lisinopril, metoprolol and SL nitro
Term
asymptomatic atherosclerosis--> stable angina-->
Definition
unstable angina--> non ST elevation AMI --> ST elevation AMI (acute coronary syndrome)
Term
ischemia
Definition
oxygen supply does not meet oxygen demand
Term
dynamic obstruction
Definition
spasm in blood vessel, separate from blockage
Term
eccentric (75%)
Definition
plaque does not fully cover the blood vessel, just in parts of vessel
Term
concentric (25%)
Definition
full coverage of plaque on vessel wall
Term
fixed obstruction
Definition
eccentric, concentric blockage due to plaque
Term
unstable plaques
Definition
occlude <50% of vessel lumen, large/soft lipid core, irregular border, thin fibrous cap
Term
thin fibrous cap
Definition
high in macrophage content, low in smooth muscle cells and collagen
Term
factors affecting plaque rupture
Definition
mechanical injury, circadian rhythm, inflammation, infection
Term
ST segment depression
Definition
T-wave inversion
Term
ST segment elevation
Definition
new bundle branch block
Term
Left Anterior Descending Artery
Definition
anterior wall of the LV, highest rate of mortality, heart failure may develope
Term
Circumflex
Definition
lateral wall of LV
Term
right coronary artery
Definition
inferoposterior wall of LV, portions of right ventricle, bradycardia and heart block
Term
pre-hospital/ early ER care
Definition
obtain IV access, ECG, draw labs, and MONA
Term
morphine
Definition
chest pain, peripheral arterial dilation, slows heart rate, decrease anxiety, decreases myocardial O2 demand
Term
oxygen
Definition
administered to patients with O2 sat <90, reasonable for all PTs for first 6 hours
Term
Nitroglycerin
Definition
relieves ischemia via coronary/peripheral vasodilation
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