Term
|
Definition
| process that maintains pH in body fluids |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| pH less than 6.8 or more than 8 |
|
|
Term
| pH specific disturbances in body |
|
Definition
| protein confirmation, excitability of neurons, potassium balance, cardiac arrhythmians, vasodilation |
|
|
Term
| Mechanisms against pH balance disturbances: |
|
Definition
1. Buffering of H+
2. Respiratory compensation
3. Renal Compensation |
|
|
Term
| Quickest defence in pH disturbance |
|
Definition
|
|
Term
|
Definition
| pairs of moleculres that bind free H+ or release them depending on whats needed |
|
|
Term
| Most important ECF buffers- |
|
Definition
|
|
Term
| most important ICF buffers- |
|
Definition
|
|
Term
| 2nd line of defense in pH disturbance |
|
Definition
| respiratory compensation (within minutes) |
|
|
Term
| Respiratory compensation- |
|
Definition
varies ventilation
an increase in vent= decreased CO2
decrease in vent= increased CO2 |
|
|
Term
| IN respiratory compensation for acidosis what detects it? |
|
Definition
| peripheral chemoreceptors detect plamsa acidity |
|
|
Term
| 3rd line of defense in pH disturbances |
|
Definition
| renal compensation, takes hours to days |
|
|
Term
|
Definition
| regulates excretion of H+ and bicarbonate in urine |
|
|
Term
| During Renal Compensation of increased acidity of body fluids causes: |
|
Definition
increased secretion of H+
increased reabsorption of BiCarb
3. increased synthesis of new bicarb |
|
|
Term
| proximal tubules job in renal comp |
|
Definition
| bicarb reabsorption coupled to h+ secretion |
|
|
Term
| distal tubule job and collecting duct in renal comp- |
|
Definition
|
|
Term
|
Definition
| carbonic acid releases H+ to make pH more acidic, ventilation is reduced so CO2 accumulates, H+ secretion in kidneys is reduced, and bicarb reabsorption is decreased |
|
|
Term
| Primary causes of deviations from normal PH |
|
Definition
respiratory acidosis or alkalosis
metabolic acidosis or alkalosis |
|
|
Term
Respiratory acidosis causes:
Compensation: |
|
Definition
hypoventilation, increased CO2
Renal |
|
|
Term
Respiratory alkalosis
Compensation: |
|
Definition
hyperventilation, decreased CO2
Renal |
|
|
Term
Metabolic Acidosis cause:
Compensation: |
|
Definition
high protein and fat diet, heavy exercise, severe diarrhea
respiratory compensation- increased ventilation
renal compensation more bicarb less H+ |
|
|
Term
Metabolic Alkalosis cause
Compensation: |
|
Definition
excess vomiting, consumption of base. not enought H+
Respiratory (decrease vent)
Renal (decrease loss of H+) |
|
|
