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AChE Inhibitor
AChE Inhibitor
8
Pharmacology
Professional
11/01/2011

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Cards

Term
Neostigmine
Definition
Acetylcholinesterase Inhibitors:
Reversible
Term
Physostigmine
Definition
Acetylcholinesterase Inhibitors:
Reversible
Term
Edrophonium
Definition
Acetylcholinesterase Inhibitors:
Reversible
-very short acting, diagnose Myasthenia Gravis
Term
Diisopropyl fluorophosphate (DFP)
Definition
Irreversible AChE Inhibitor: Organophosphates
Term
Nerve Gases
Definition
Irreversible AChE Inhibitor: Organophosphates
Term
Echothiophate
Definition
Irreversible AChE Inhibitor: Organophosphates
-no CNS (Quaternary ammonium ion won't cross BBB)
Term
2-pralidoxime (2-PAM)
Definition
Acetylcholinesterase Reactivator
Term
ACh Inhibitors in general
Definition
like muscarinic agonists! w/Nm and Nn effects as well
-open angle glaucoma
-paralytic ileus- urinary retention
-myasthenia gravis- treatment and diagnosis (edrophonium)
-dry mouth (xerostomia)
-atropine toxicity
-anesthesia- reverses NMJ block
-paroxysmal atrial tachycardia (PAT)- increases vagal tone in heart and slows heart rate
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