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ABx Unit 1
Therapy 3
76
Pharmacology
Graduate
01/21/2016

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Term
Colisitin
Definition
Gram-
MDRO
Acinetobacter
Pseudomonas
Klebsiella
CRE
Term
Polymyxin B
Definition
Gram-
MDRO
Acinetobacter
pseudomonas
Klebsiella
CRE
Term
Dalbavancin
Definition
Gram+
MRSA
Long t 1/2
Term
Oritavancin
Definition
Gram+
MRSA
Long t 1/2
Term
Daptomycin
Definition
MSSA
MRSA
Enterococci VRE
Streptococci
Term
Linezolid
Definition
MSSA
MRSA
Streptococci
Enterococci VRE
Term
Tedizolid
Definition
MSSA
MRSA
Streptococci
Enterococci VRE
Term
Clindamycin
Definition
Gram+
Anaerobes
Plasmodium
Term
Ciprofloxacin
spectrum
Definition
Enteric GNR
Gram-
H. Influenza
pseudomonas
Term
Penicillin G and V
Definition
Most Streptococci
Oral Anaerobes
Peptostreptococci
Actinomyces
Trrponema pallidum
Term
penicillin G Benzathine LA
spectrum
Definition
one dose
lasts 1-4 weeks
Bicillin LA
Term
Penicillin G Benzathine/procaine CR
spectrum
Definition
Bicillin CR
dosed BID
Term
Amoxicillin
Ampicillin
spectrum
Definition
Streptococci
Enterococci
Listeria
H. Influenzae
Term
Piperacillin
Definition
Psuedomonas Aeruginosa
Streptococci
Enterococci
Term
Amox-Clav
Spectrum
Definition
MSSA
Streptococci
Enterococci
Enteric GNR
Term
Ampicillin-Sulbactam
spectrum
Definition
MSSA
Streptococci
Enterococci
Enteric GNR
Anaerobes
Acintobacter
Term
Piperacilllin-Tazobactam (Zosyn)
Spectrum
Definition
MSSA
Streptococci
Enterococci
Enteric GNR
Psedomonas Aeruginosa
Term
Beta lactams are bectercidal or bacteriostatic?
Definition
Bectercidal
Term
what drugs can lead to non-allergic rash?
Definition
Amoxicillin
Amicillin
Term
Oxacillin
Nafcillin
Dicoxacillin
spectrum
Definition
Staph
MSSA
Streptococci
Term
should dicloxacillin be taken with or without food?
Definition
With food
Term
Which Gram_ bacteria do all PCN hit?
Definition
Streptococci
Term
What two combo drugs can be converted to each other 1:1
Definition
Amox-Clav and Amp-Sulbactam
Term
What drug interacts with all PCN?
Definition
Methotrexate
Term
Cephalexin
Cefazolin
Definition
MSSA
Streptococci
Term
What are the 2nd generation Cephalosproins?
Definition
Cefuroxime, Cefprozil, Cephmycins, Cefoxitin, Cefotetan
Term
Which two cephalosporins cover GI anaerobes
Definition
Cefotetan, Cefoxitin
Term
Name the 3rd generation cephalosproins?
Definition
Ceftriaxone, Cefotaxime, Cefdidnir,Cefixime, Ceftazidime
Term
2nd generation cphalosproins spectrum?
Definition
Haemophilus
Some enteric GNR
Term
What do 3rd generation Cephalosporins cover?
Definition
Streptococci
Enteric GNR
Pseudomonas-CTZ
Term
What generation is the broad spectrum cephalosporin and what is its name
Definition
4th Cefepime
Term
What unique bacteria does Cefteroloine cover
Definition
MRSA
Term
What bacteria class should never be treated with Gen 1-4 sephalosporin
Definition
eneterococci
Term
Cephtolozone/ Tazobactam
spectrum
Definition
Enterobacteriacae
ESBL
Psuedomonas
Term
What is a unique side effects of cephalosporin/BLI
Definition
Pyrexia-drug induced fever
Term
ertapenem
Definition
MSSA
Streptococci
enteric GNR
ESBL producers
Anaaerobes
Term
Meropenem
doripenem
Definition
MSSA
Streptococci
Enteric GNR
Pseudomonase
ESBL producers
actineobacter
amaerobes
Term
carbapenem ADR
Definition
Seizures
Term
Carbapenem DDI
Definition
Valproic Acid
Term
the only mnobactam and what is its spectrum
Definition
Aztreonam
Bram- aerobis bacteria
Term
name the three macrolides
Definition
Clarithromycin
Azithromycin
erythromycin
Term
are macrolides bactericidal or bacteriostatic
Definition
Bacteriostatic
Term
macrolides spectrum?
Definition
H. influenza
M. catarrhalis
Term
ADR of Macrolides
Definition
CYP3A4 inhibitor
QY prolongation
Term
Nitrofurantoin
Spectrum
Definition
trapped in urine
E.colli
staph
enterococci
Term
Fosfomycin
spectrum
Definition
Ecoli
Klebsiella
Proteus
Enterobacteriacae
Enterococci
Some VRE
Term
Where in the body does fosfomycin work
Definition
lower urinary tract
Term
Fosfomycin DDI
Definition
Antacid
take on empty stomach
Term
Metronidazole
spectrum
Definition
Obligate anaerobes
clostridium
protozoa
giardia
Trichamonas
H.pylori
Term
Metronidazole
ADR
Definition
Pargeusia-metal taste
Neuropathies
Term
Metronidazole
DDI
Definition
Booze
Warfarin increased INR
Term
TMP/SMX
Spectrum
Definition
Gram-
H.influenzae
listeria
Gram+
Staph
Some MRSA-community acquired
Term
Baactrim
ADR
Definition
Dehydration
photosensitivity
increase INR
increase SCr
Term
how is Bactrim dosed?
Definition
Based on TMP ratio 1:5 TMP:SMX
Term
name FQ
Definition
Ciprofloxacin
Levofloxacin
Moxifloxacin
Gemfloxacin
Term
Levofloxacin, moxifloxacin
spectrum
Definition
Strep pneumonia
Enteric GNR
H. influenza
Psuedomonas
MSSA
Term
re FQ concentration or time dependent killers?
Definition
Concentration
Term
Which FQ are for Urinary and which for respiratory
Definition
Cipro-urinary
Rest respiratory
Term
What ABx effects DM patients
Definition
FQ
Term
FQ
ADR
Definition
QT prolongation
Tendon rupture
Term
what two categories of ABx should not be taken with ABx
Definition
Tetracyclines
FQ
Term
What ABx is for Lyme disease
Definition
Tetracycline
Term
name tetracycline
Definition
Doxycycline
Teracycline
Minocycline
Term
Tetracycline
spectrum
Definition
B. Burgdoeferi
plasmodium
Term
Which ABx should never be given to children<8y/o?
Definition
Tetracycline
Term
Tigecycline
spectrum
Definition
S. Pneumonia
Staph
enterococci
Atypicals
Term
why shouldn't Tigeycline be used for bacteremia
Definition
because it doesn't stay in the blood it goes into the tissu
Term
What drugs have DDI with NMB?
Definition
Clindamycin
Term
What ABx is contraindicted with SSRI and MAOi
Definition
Linezolid
Term
which ABx is a cyclic lipopeptide
Definition
Daptomycin
Term
Is daptomycin bactericidal or bacteriostatic
Definition
Batercidal
Term
which ABx cannot be used in the lungs due to getting stuck in the surfactant
Definition
Daptomycin
Term
which ABx cannot be used with statins
Definition
daptomycin
Term
name the lipoglycopeptides
Definition
Dalbavancin
Oritavancin
Term
are lipoglycopeptides Dalbavancin and Oritavancin bactericidal or bacteriostatic
Definition
bactericidal
Term
name the polymyxins
Definition
colisitin
Polymyxin B
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