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AALAS LATG Exam Preperation
Personal Weakness Study
113
Other
12/21/2008

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Cards

Term
What best defines “randomization” in biomedical research?
Definition
It is a method of distributing animals among the different groups needed for the study.
Term
Which of the following does not cause enteritis in hamsters?
Definition
Mycoplasma spp.
Term
According to statistics, what percentage of the people who work with laboratory animals develop allergic symptoms?
Definition
30
Term
According to statistics, what percentage of the people who work with laboratory animals develop allergic symptoms?
Definition
30
Term
What is the role of cytokines?
Definition
They serve to transmit information about the presence of a foreign substance from the receptor molecule to other molecules and cells of the immune system.
Term
What is an example of an activity that reflects the transcendence level in Maslow’s hierarchy of needs?
Definition
Mentoring a subordinate
Term
Which of the following is not a recommendation included in the section of the manual describing the hiring process?
Definition
The job description should specifically list all the tasks that the employee will need to perform.
Term
Adding an analgesic sedative to ketamine administration has which of the following effects?
Definition
It prevents muscle rigidity.
Term
The function of various brain regions have been mapped using which technique?
Definition
Positron emission tomography
Term
For small scale accidents in the facility, in what order should the following three steps be taken?
Definition
Leave the area, call for help, secure the area.
Term
Which of the following are true of axenic animals as compared to animals with normal microflora?
Definition
They have generally lower enzyme levels.
Term
Microfilaria isolated from fresh blood smears are an indication that the animal suffers from which disease?
Definition
Heartworms
Term
Where does translation take place?
Definition
In the ribosomes
Term
Which of the following is not required by FDA GLPs standard operating procedures?
Definition
Staff PPE use
Term
Pharmacologists who develop new drugs or modify existing drugs to reduce their side effects, for example, would probably regularly use a drug classification system based on which feature?
Definition
Chemical structure
Term
What is another term for macrophages?
Definition
Antigen-presenting cells
Term
Isolators must have what device to allow materials to pass through to the isolator without contaminating the animals?
Definition
Port
Term
What is a major advantage of fluoroscopy over standard radiography?
Definition
It takes moving pictures.
Term
What is Bremsstrahlung?
Definition
X-ray produced by beta particles when they decelerate
Term
Which of the following statements represents the type of comments the supervisor should use in commenting on a completed task?
Definition
"Next time, you need to use the other disinfectant."
Term
Why is cyclosporin A often used in individuals who have received tissue transplants?
Definition
It is an immunosuppressant drug
Term
Which of the following characteristics does not apply to morphine?
Definition
It causes an increase in respiratory rate.
Term
In which techniques is the x-ray beam rotated 360° around the patient to allow precise location of lesions?
Definition
Computed tomography
Term
Why is neomycin not given by the enteral route?
Definition
It is toxic.
Term
Which is the stage when a protozoan parasite actively multiplies?
Definition
Trophozoite
Term
Which of the following statements apply to antibodies?
Definition
They are produced in plasma cells.
Term
What is a common side effect of anethesia induced with pentobarbital?
Definition
Hypothermia
Term
Salmonella, Shigella, and Streptococcus are often identified by which characteristic?
Definition
Serological typing
Term
If you read an article that states that the results showed a significant difference at the 0.05 level, what does this mean?
Definition
There is a 95% probability that the difference is real.
Term
For an aerosol to be used inhalation therapy, the particles must be smaller than what size?
Definition
5 µm
Term
In a study that attempts to determine if using treats such as pieces of carrots to elicit a desired behavior in rats (move through a tunnel to a new cage) helps the rats learn the behavior quicker, what would the independent variable be?
Definition
The treats
Term
Which of the following statements regarding atrophic rhinitis is true?
Definition
There is little that can be done to reverse the damage from atrophic rhinitis once it has occurred.
Term
Who is responsible for providing security-related training to all staff in an animal facility?
Definition
The animal facility’s veterinary and supervisory staff
Term
What is one reason to use a pre-anesthetic treatment?
Definition
Reduce the amount of anesthetic needed
Term
In rebreathing systems, the concentration of anesthetic is usually expressed as which of the following?
Definition
Percentage of anesthetic gas in fresh air
Term
What best describes polyclonal antibodies?
Definition
They are groups of antibodies that react with different sites on the same antigen.
Term
Which of the following represents a difference between hysterectomy derivation and embryo transfer?
Definition
In one case the embryos are at term and in the other case, the embryos used are at an earlier stage of development.
Term
Which of the following statements apply to haploid cells?
Definition
They are the germ cells.
Term
In rebreathing anesthesia systems, what reaches the animal’s lungs?
Definition
A mixture of fresh and exhaled gases
Term
What best describe a mutation?
Definition
A permanent change in the DNA sequence in some or all of an animal’s cells
Term
What does an antibody titer measure?
Definition
The lowest dilution of the blood sample that gives a positive result when exposed to the antigen
Term
Where does replication take place?
Definition
In the nucleus
Term
Researchers who work with serum, blood, or tissues from humans or apes should receive what vaccine?
Definition
Hepatitis B
Term
How is the mouse thymic virus detected?
Definition
Indirect immunoflurorescence assay
Term
Which of the following agents has been nicknamed the "injectable gas?"
Definition
Propofol
Term
If the plasma appears cloudy in the hematocrit tube, it could be an indication of which condition?
Definition
Hyperlipemia
Term
In AIDS, the HIV virus destroys which of the cells involved in the immune response?
Definition
T helper cells and macrophages
Term
The concentration of which of the following is usually expressed as grams per deciliter (g/dL)?
Definition
Hemoglobin
Term
Which technique allows real time moving images to be observed?
Definition
Fluoroscopy
Term
Pregnancy and allergic reactions are two conditions that often cause an elevation in which white blood cell type?
Definition
Eosinophils
Term
Which of the following statements apply to all bacteria?
Definition
They do not have mitochondria in their cytoplasm.
Term
What imaging technique allows the observation of biological processes as they occur?
Definition
Positron emission tomography
Term
Atropine and glycopyrrolate belong in which of the following types of drugs?
Definition
Anticholinergics
Term
What is an inflammation of the upper respiratory tract in swine associated with Bordetella bronchiseptica and Pasturella multocida?
Definition
Atrophic rhinitis
Term
Which of the following statements is true of nonrebreathing systems?
Definition
They produce large amounts of WAGs
Term
Which of the following describes Carbon-14 (14C), tritium (3H), and Iodine-125 (125I)?
Definition
radioisotopes
Term
Contagious ecthyma is also known as _______ or _____________.
Definition
orf, sore mouth
Term
Which pinworm infection can be detected by a tape test?
Definition
Syphacia
Term
Which of the following drugs can reverse the effect of opioids?
Definition
Nalorphine and naloxone
Term
The presence of a pathogen in the animals procured from a vendor may not be detected by the health surveillance program for up to how long?
Definition
up to 3 months
Term
Dose rates are generally expressed as
Definition
mg/kg.
Term
Which of the following carbohydrates is a monosaccharide?
Definition
Glucose
Term
The ability to clearly relate the facility’s goals to the staff is an example of:
Definition
communication skills.
Term
What is the most common disease of freshwater fish maintained in aquaria in institutional settings?
Definition
Microsporidiosis
Term
When wild type females are bred to hemizygous males, what percentage of the offspring can be expected to have the transgene?
Definition
50%
Term
What is the predominant type of immunoglobulins found in the saliva of mammals?
Definition
IgA
Term
What does the term “drug spectrum” refer to?
Definition
The type of organisms it is effective against
Term
What is the product of translation?
Definition
Protein
Term
Enzootic pneumonia is caused primarily by which pathogen?
Definition
Mycoplasma spp.
Term
What additional publication from USDA clarifies the intent of the Animal Welfare Act?
Definition
The Animal Care Policy Manual
Term
Which class of biosafety cabinets offers the most protection to personnel?
Definition
Class III
Term
Which of the following scientists are associated with the development of the basic concepts of immunology?
Definition
Jenner and Pasteur
Term
What best describes alpha particles?
Definition
They consist of two protons.
Term
What is a characteristic of the respiratory pattern of surgical anesthesia?
Definition
Breathing initiated in the thoracic-abdominal area
Term
Which of the following zoonotic viral disease often remains asymptomatic in infected macaques and can be fatal in humans?
Definition
Cercopithecine herpevirus I
Term
Which agency administers the Animal Welfare Act?
Definition
APHIS
Term
What term describes lice infestation?
Definition
Pediculosis
Term
Which of the following treatments is commonly used in laboratory animals to prevent transplant rejection?
Definition
Radiation exposure to kill immune system cells
Term
The confidence level is an index of:
Definition
certainty.
Term
The cost for personnel generally represents what percentage of an animal facility’s budget?
Definition
More than 60%
Term
Among the red blood indices, which one provides information about the average size of the individual red blood cells?
Definition
Mean corpuscular volume
Term
Why are adjuvants used in vaccines?
Definition
To enhance the immune response
Term
What does an ultrasonic doppler flow detector measure?
Definition
Blood pressure
Term
Which of the following applies to certified feeds?
Definition
The concentration of contaminants is below maximum acceptable levels.
Term
Mycobacteriosis in fish is thought to spread through which of the following?
Definition
Cannibalism of dead tank mates
Term
Antibody-mediated immune response is associated with which kind of cells?
Definition
B cells
Term
What is another name for infectious tracheobronchitis?
Definition
Kennel cough
Term
The introduction of an antibiotic resistance gene into a DNA fragment is used for what purpose?
Definition
It helps identify the cells that have integrated the transgene.
Term
Using an anticholinergic before anesthesia helps prevent which of the following?
Definition
Choking while under anesthesia
Term
If you are anesthetizing a 5 kg dog using a rebreathing system, what capacity would you choose for the rebreathing bag?
Definition
100 ml
Term
Describe a good way to give an anesthetic "to effect" using the intravenous route.
Definition
Half the dose is injected at once, the rest is injected in small amounts as needed until the desired stage of anesthesia is reached.
Term
Which organization has developed standards and guidelines to help prevent the transmission of zoonoses through importation of animals?
Definition
The World Organization for Animal Health
Term
What are the three steps involved in an acquired immunity response to a foreign substance?
Definition
Recognition, processing, response
Term
Abdominal distention, dehydration, tooth grinding and a sloshing sound when the abdomen is palpated are clinical signs of which rabbit disease?
Definition
Mucoid enteropathy
Term
What easily observable signs could suggest a diagnosis of dermatophytosis?
Definition
Crusty lesions around a few hairs or a slight scaliness of the skin
Term
Which of the following are the weakest bonds in DNA?
Definition
Base-base
Term
Which immune system cells secrete antibodies?
Definition
Plasma cells
Term
What best describe the "community right-to-know" regulations?
Definition
A list of all hazardous materials present in the facility must be made available to local emergency response groups.
Term
An anesthetic log should be kept for each animal. How often should vital parameters be recorded?
Definition
Every 10-15 minutes
Term
A mycelium is formed by which of the following?
Definition
A mold colony
Term
As a radioactive substance decays, the energy and particles that are emitted are referred to by which term?
Definition
Radiation
Term
Which of the following is not a major difference between the structure and chemical makeup of DNA and RNA?
Definition
DNA has nitrogenous bases while RNA has hydrogenous bases.
Term
How often should a research facility using regulated species update their USDA registration?
Definition
Every 3 years
Term
hich of the following is not a common gastrointestinal conditions in laboratory rabbits?
Definition
Mycoplasmosis
Term
What is the primary reason for the establishment and maintenance of a breeding colony?
Definition
To produce animals of a specific genotype
Term
Which of the following drugs is a dissociative agent?
Definition
Ketamine
Term
How often must the PHS assurance be resubmitted?
Definition
Every 5 years
Term
How should a urine sample for microbiological analysis be obtained?
Definition
Perform a cystocentesis.
Term
What disease can cause fatal respiratory disease in newborn and weanling mice?
Definition
Sendai virus
Term
Which of the following statements represents the type of comments the supervisor should use in commenting on a completed task?
Definition
"Next time, you need to use the other disinfectant."
Term
Xylazine is which type of drug?
Definition
Alpha-2 adrenergic agonist
Term
What best describes category C animals?
Definition
Animals not experiencing pain or distress
Term
What does the term “gnotobiotics” mean?
Definition
Well-known life