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A&P 9.19
Slides 11 -
24
Biology
Undergraduate 3
09/19/2012

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Term
DA(change in)C
---------------
d
Definition
Rate of NET diffusion of solute across the membrane (Fick's Law)
D = diffusion coefficient
A = surface area of the membrane
DC = concentration difference across the membrane
d = thickness of the membrane
Term
DA(change in)C
---------------
d


D = ???
A = surface area of the membrane
DC = concentration difference across the membrane
d = thickness of the membrane
Definition
diffusion coefficient
Term
DA(change in)C
---------------
d


D = diffusion coefficient
A = ???
DC = concentration difference across the membrane
d = thickness of the membrane
Definition
surface area of the membrane
Term
DA(change in)C
---------------
d


D = diffusion coefficient
A = surface area of the membrane
(change in)C = ???
d = thickness of the membrane
Definition
concentration difference across the membrane
Term
DA(change in)C
---------------
d


D = diffusion coefficient
A = surface area of the membrane
(change in)C = concentration difference across the membrane
d = ???
Definition
thickness of the membrane
Term
Diffusion is the movement of molecules from an area of high concentration to an area of low concentration. The area of high concentration is called the ??? solution and the area of low concentration is called the intracellular solution.
Definition
extracellular
Term
Diffusion is the movement of molecules from an area of high concentration to an area of low concentration. The area of high concentration is called the extracellular solution and the area of low concentration is called the ??? solution.
Definition
intracellular
Term
Water, dissolved gases like oxygen O2 , carbon dioxide CO2 and nitric oxide NO and ??? soluble molecules like fatty acids and steroids can diffuse easily across the phospholipid bilayer.
Definition
lipid
Term
Most ??? molecules ( K+, Na+, Ca2+, amino acids, monosaccharides, etc.) cannot pass directly through the phospholipid bilayer.
Definition
hydrophillic
Term
To cross the membrane, most hydrophilic molecules must pass through ??? or be transported across by protein carriers.
Definition
protein channels
Term
To cross the membrane, most hydrophilic molecules must pass through protein channels or be transported across by ???.
Definition
protein carriers
Term
If the hydrophilic molecules are aided through the membrane down their concentration gradient, then we call it ???.
Definition
facilitated diffusion
Term
carrier proteins are also called ???
Definition
membrane transporters
Term
During facilitated diffusion,
important ??? (glucose, fatty acids, etc.) are typically acted upon in some way as soon as they enter the cell. This keeps the intracellular concentration of the metabolite low, thereby facilitating further uptake.
Definition
metabolites
Term
Unlike simple diffusion, ???

is mediated by membrane proteins

is highly selective to one (or a few) specific solutes

transport rates are susceptible to acute and chronic regulation
Definition
facilitated diffusion
Term
Unlike simple diffusion, facilitated diffusion…

is mediated by ???

is highly selective to one (or a few) specific solutes

transport rates are susceptible to acute and chronic regulation
Definition
membrane proteins
Term
Unlike simple diffusion, facilitated diffusion…

is mediated by membrane proteins

is highly selective to one (or a few) specific ???

transport rates are susceptible to acute and chronic regulation
Definition
solutes
Term
Unlike simple diffusion, facilitated diffusion…

is mediated by membrane proteins

is highly selective to one (or a few) specific solutes

transport rates are susceptible to ??? and chronic regulation
Definition
acute
Term
Unlike simple diffusion, facilitated diffusion…

is mediated by membrane proteins

is highly selective to one (or a few) specific solutes

transport rates are susceptible to acute and ??? regulation
Definition
chronic
Term
??? – changed quickly (usually within minutes)
Definition
acute regulation
Term
??? – changed over time (usually days, weeks, months, etc…)
Definition
chronic regulation
Term
??? form permanent water-filled pores that span the membrane.
Definition
channels
Term
The pore of an ion channel has a selectivity filter so that only particular ions can pass through.

selectivity is based on both ??? and charge
Definition
size
Term
The pore of an ion channel has a selectivity filter so that only particular ions can pass through.
Selectivity is based on both size and ???
Definition
charge
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