Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Amino Acids in hemoglobin |
|
Definition
|
holds heme group which hold irons which interacts with oxygen for pigment
|
|
|
Term
|
Definition
|
`10% dissolved, 30% on hemoglobin, 60% on carbonic acid
|
|
|
Term
|
Definition
|
loses nucleus before bone marrow
|
|
|
Term
|
Definition
|
|
Term
| Erythropoietin control of erythopoiesis |
|
Definition
|
monitors oxygen delivery in kidneys. effector site is bone marrow and makes more RBC
|
|
|
Term
|
Definition
|
spleen (red) -> liver (green-bile) -> GI tract (brown)
|
|
|
Term
|
Definition
|
40-70%. picks up neither basic or acidic. dangerous enzymes, first to arrive. Phagocyte
|
|
|
Term
|
Definition
|
picks up acidic dye. allergic response. 1-7%. worm infestation.
|
|
|
Term
|
Definition
|
0-1%. basic blue dye. histamine (inflammation) and heparine (prevents clotting)
|
|
|
Term
|
Definition
|
largest, come later, kill better. 4-8%. Phagocyte or isolate.
|
|
|
Term
|
Definition
|
Platelets- portion of cells from marrow for clotting
|
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Common Pathway to Clotting |
|
Definition
|
Calicum, platelet phospholipid, prothrombin, thrombin, fibrinogen, fibrin, clot
|
|
|
Term
|
Definition
|
plasminogen (inactive), plasmin (active, breaks down clot)
|
|
|
Term
|
Definition
|
connective tissue between two sides of heart
|
|
|
Term
|
Definition
|
= pressure1-pressue2/resistance
|
|
|
Term
|
Definition
|
= number of molecule/size of box
|
|
|
Term
|
Definition
|
highest leak of Na+ comes to threshold 100 times/min. paces rest of system
|
|
|
Term
|
Definition
|
between right and left atrium
|
|
|
Term
| Atrioventricular (AV) node |
|
Definition
|
can comes to threshold without SA node
|
|
|
Term
|
Definition
|
if it dies, put in pacemaker. electrical conduction goes through here.
|
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
depolarization of ventricle
|
|
|
Term
|
Definition
|
depolarization of ventricles
|
|
|
Term
|
Definition
|
late diastole; from T to P for next QRS
|
|
|
Term
| Isovolumetric ventricular contraction |
|
Definition
|
early systole; ventricle begins to contract but not pumping out any blood. volume stays the same. first heart sound.
|
|
|
Term
|
Definition
|
late systole; pump out of ventricle before atrium contracts
|
|
|
Term
|
Definition
|
early diastole; no blood flow. 2nd heart sound
|
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
amount pumped out (65-75)
|
|
|
Term
|
Definition
|
Stroke volume/end diastolic volume
|
|
|
Term
|
Definition
|
heart rate X stroke volume
|
|
|
Term
| Pressure in R. and L. ventricle |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
must have Nitrous Oxide to keep hemoglobin carrying oxygen
|
|
|
Term
| Controls of Cardiac Output (3 physical, 2 neuroendocrine) |
|
Definition
|
respiratory pump, skeletal muscle pump, venous constriction, sympathetic and parasympathetic
|
|
|
Term
|
Definition
|
lumen, tunica intima (epithelial tissue), tunica media (smooth muscle), tunica adventitia (conn. tissue, tough)
|
|
|
Term
|
Definition
|
|
Term
|
Definition
|
Continuous (1-blood brain), Fenestrated (2-GI tract, kidneys), Sinusoids (multiple- liver)
|
|
|
Term
| Hepatic Portal Circulation |
|
Definition
|
nutrients and oxygen to liver. direct delivery. 1st cap in GI tract -> liver ->portal vein -> 2nd cap in liver -> hepatic vein -> inferior vena cava
|
|
|
Term
| Hypophyseal Portal Circulation |
|
Definition
|
1st cap -> hypo portal vein -> 2nd cap -> pituitary vein -> superior vena cava. delivers releasing hormones
|
|
|
Term
|
Definition
|
pumping into arteries, highest
|
|
|
Term
|
Definition
|
pumping out of arteries, lowest
|
|
|
Term
|
Definition
|
|
Term
| MAP estimate in resting condition |
|
Definition
|
DP + 1/3PP = MAP ~93 mmHG
|
|
|
Term
|
Definition
|
DP + 1/2 PP = MAP. ~ 100mmHG
|
|
|
Term
|
Definition
|
length of tube X fluid viscosity/ radius of tube^4
|
|
|
Term
|
Definition
|
|
Term
| Blood Flow through Organs (BFo) |
|
Definition
|
|
Term
| Control of MAP: Baroreceptors |
|
Definition
|
Carotid and Aortic Baroreceptors, hypothalamus & medulla, Increase sympathetic, Heart muscle( HR&SV), Arterioles (Contrict-TPR, Veins (Contrict- VR EDV SV), Increase MAP
|
|
|
Term
|
Definition
|
Kidney Barorecptors, Kidneys, Increase Renin- Angiotensin and Aldosterone, Arterioles (Constrict- TPR), Kidneys (NA+ and H2O retention, VR EDV SV), Increase MAP
|
|
|
Term
| Control of MAP: Hypothalamic |
|
Definition
|
Hypothalamic Baroreceptors, Hypothalamus, Increase ADH (vasopressin), Arterioles (constrict- TPR), Kidneys (H2O retention- VR, RDV, SV), Increase MAP
|
|
|
Term
| Control of MAP: Capillary |
|
Definition
|
Effects Capillaries, Water shifts into them, Increase VR EDV SR, Increase MAP
|
|
|
Term
| Renin Angiotensin Aldosterone |
|
Definition
|
Liver releases angiotensinogen, Decrease MAP, Kidneys release renin, activates angiotensin, Increase TPR and Adrenals release aldosterone, Kidneys salt water retention, Increase SV
|
|
|
Term
| Increases of blood flow in exercise |
|
Definition
|
heart, skeletal muscle, skin
|
|
|
Term
|
Definition
|
Filtration - absorption. positive is out, negative is in
|
|
|
Term
|
Definition
|
out, hydrostatic pressure in capillaries (35) - hydrostatic pressure in intersititum (usually 0)
|
|
|
Term
|
Definition
|
in, colloid osmotic pressure in capillaries (28) - colloid osmotic pressure in intersisitium (3)
|
|
|
Term
|
Definition
|
formation by net filtration from blood. returned to venous circulation. Water, crystalloids, proteins, fats, WBC. (NO RBC)
|
|
|
Term
| Functions of respiratory system |
|
Definition
|
exchange of gases, regulation of pH, defenses, emotion and expression
|
|
|
Term
|
Definition
|
gas exchange. Type 1: squamous epithelia, Type 2: surfactant producing, alveolar macrophages (WBC, defenses)
|
|
|
Term
|
Definition
|
diaphragm for resting, external intercostals aid deep breaths
|
|
|
Term
|
Definition
|
passive when resting, internal intercostals and ab muscles
|
|
|
Term
|
Definition
|
pressure in alv - pressure in atm/ resistance
|
|
|
Term
| Pressure in alveolar during inspiration and expiration |
|
Definition
|
less than 0 air in, end of inspiration no air flow- lungs = pressure in atm, elastic recoil pressure greater than 0, pressure same as atm at end of expiration- no air flow
|
|
|
Term
| Contraction Control in Bronchiole Smooth Muscle |
|
Definition
|
Neuro -> ANS -> Para. -> Cholinergic receptors -> contraction -> constriction. Local -> decrease CO2 -> Contraction -> constriction
|
|
|
Term
| Dilation Control in Brochiole Smooth Muscle |
|
Definition
|
Neuro -> ANS -> epi -> Beta 2 receptors -> Relaxation -> Dilation. Local -> Increase CO2 -> Relaxation -> Dilation
|
|
|
Term
|
Definition
|
overcomes surface tension to increase compliance and decrease work of breathing. Type 2 cells produce phospholipid, sits in between water molecules
|
|
|
Term
|
Definition
|
|
Term
| Inspiratory reserve volume |
|
Definition
|
3000 ml. additional air that can be inhaled.
|
|
|
Term
| Expiratory reserve volume |
|
Definition
|
1 liter. additional air you can exhale after normal exhalation.
|
|
|
Term
|
Definition
|
1 liter. amount of air left in lungs after maximal exhalation.
|
|
|
Term
|
Definition
|
|
Term
| Functional Residual Capacity |
|
Definition
|
2 liters. residual + expiratory residual
|
|
|
Term
|
Definition
|
5 liters. everything minus out.
|
|
|
Term
|
Definition
|
|
Term
| Minute Respiratory Volume |
|
Definition
|
|
Term
|
Definition
|
space with no gas exchange. 150 ml.
|
|
|
Term
| Calculation of alveolar ventilation |
|
Definition
|
|
Term
| Reflex Control of Ventilation |
|
Definition
|
increase in CO2 and H in CSF and carotid &aortic bodies -> vagus and glossopharyngeal nerves -> medullary respiratory neurons, forced expiration, autorhythmic (pons) -> phrenic and intercostal nerves -> diaphragm and intercostal muscles -> increase ventilation
|
|
|
Term
| Brain Stem Control of Ventilation (Pons) |
|
Definition
|
direct for H=, pneumotaxic center, inhibits inspiratory, shorten inspiration, smooths ventilation
|
|
|
Term
| Voluntary Control of Ventilation |
|
Definition
|
speech, swallowing, coughing, crying, ect., cerebral cortex, varies with activity
|
|
|
Term
| Time for RBS equilibrium to occur |
|
Definition
|
|
Term
| Bronchial Smooth Muscle Prediction |
|
Definition
|
increased Co2 = dilation. decreased CO2 = constriction
|
|
|
Term
| Pulmonary arterial Smooth Muscle |
|
Definition
|
MATCH BLOOD FLOW TO AIR FLOW. Increased CO2 = constriction, decreased CO2 = dilation
|
|
|
Term
| Systemic arterial Smooth Muscle |
|
Definition
|
Deliver blood flow to areas of high metabolic use. Increased CO2 = dilation. Decreased CO2 = constriction
|
|
|
Term
| Partial Pressure of Oxygen |
|
Definition
|
PP= atm pressure X % of gas. can change where you are at (lower is more pressure) or amount of oxygen (usually 20%)
|
|
|
Term
|
Definition
|
decreases MAP and filtration and net absorption. prevents pulmonary edema which slows diffusion.
|
|
|
Term
| Binding of Oxygen to Hemoglobin |
|
Definition
|
Hb+O2 -> Hb02. (replaces in lungs) HbO2 -> Hb +02 (uses in tissue)
|
|
|
Term
|
Definition
|
determines direction of reaction
|
|
|
Term
| Partial Pressure of O3 on Hb Saturation Curve |
|
Definition
|
100 mm/hg in lungs, completely saturated. 20 mm/hg in tissue. about 25% delivered, 75% reserved on hb.
|
|
|
Term
|
Definition
|
CO2 + H2O -> H2CO3 (carbonic anhydrase in tissue) revered in lungs. H+ + HCO3 in tissue, reversed in lungs.
|
|
|
Term
| Functions of Urinary System |
|
Definition
|
control of fluid, electrolyte and acid base balance, excretion of wastes, endocrine (erythropoietin, renin, vit d)
|
|
|
Term
|
Definition
|
renal cortex (outer), renal medulla (into tubes), major and minor calyces (collecting areas), renal pelvis (drains into picket then to ureter)
|
|
|
Term
|
Definition
|
|
Term
| Vascular Component of urine formation |
|
Definition
|
afferent arterioles (into capillaries), glomerulus (filtered), efferent arteriole (going out), peritubular capillaries (wrapping around tubule)
|
|
|
Term
| Tubule Component of urine creation |
|
Definition
|
Om cortex of medulla. Glomerular capsule (filters into), proximal convoluted tubule (twisting), loop of henle (countercurrent), distal convoluted tubule, collecting duct (collect nephrons)
|
|
|
Term
| Juxtaglomerular Apparatus |
|
Definition
|
secretes renin, nothing to do with urine
|
|
|
Term
| Calculation of Glomular Filtration Rate (GFR) |
|
Definition
|
amount filtered = amount excreted. Volume(u) X (C)u/ (C)p
|
|
|
Term
|
Definition
|
Active transport (Na and Ca), Cotransport (K, gl, aa, ua), Osmosis (H2O), Facilitated Diffusion (Cl, SO4, PO4), Simple Diffusion (urea)
|
|
|
Term
|
Definition
|
reabsorbs Na+ and secretes K and H. one cation for one cation.
|
|
|
Term
| Simple Diffusion secretion in urine |
|
Definition
|
|