Term
| primary + secondary roles of kidneys |
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Definition
| 1: to maintain whole body homeostasis by filtering blood. 2: acid-base balance, electrolyte regulation, blood volume, blood pressure. respond and adapt to changes. |
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Term
| kidneys secrete _____ into bloodstream to communicate with other organs |
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Definition
| erythropoietin and vitamin D |
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Term
| visceral layer of bowman's capsule |
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Definition
| podocytes w/ pedicles (foot processes) - they encase the glomerular capillaries |
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Term
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Definition
| simple cuboidal epithelium w/ microvilli brush border (so inside proximal tubule looks darker than distal - no brush border) |
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Term
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Definition
| goes into kidney medulla. thick and thin segments. thin = simple squamous. (kidney medulla = can't see glomeruli anymore) |
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Term
| how do you know whether you're looking at a thick segment of the loop of henle, a collecting duct, or one of the convoluted tubules? |
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Definition
| collecting duct is the fluffiest of them all, with distinct cell borders, and only in medulla. loop of henle is only in medulla (no glomeruli) and convoluted tubules only in cortex |
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Term
| basement membrane in kidneys |
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Definition
| basal laminae of podocytes + basal laminae of glomerular epithelium |
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Term
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Definition
| hematuria due to autoantibodies against collagen IV in the glomerular basement membrane - letting in bigger particles than usual |
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Term
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Definition
| spaces between podocyte pedicels which allow passage of fluid filtrate into bowman's space |
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Term
| where does most reabsorption occur |
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Definition
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Term
| where does Na/K regulation occur |
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Definition
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Term
| regulation of water resorption occurs in the |
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Definition
| collecting ducts, which respond to ADH |
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Term
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Definition
| = JG cells + macula densa |
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Term
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Definition
| renin-secreting specialized smooth muscle cells in afferent arterioles near the glomerulus |
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Term
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Definition
| dense cells lining DCT by glomerulus. sensitive to ionic content and water volume in DCT. produce signals that promote renin secretion by JG cells. |
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Term
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Definition
| papillary ducts converge here. it has a thick muscle wall and transitional epi. |
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Term
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Definition
| 3 muscle layers (long. circular long.) and transitional epi |
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Term
| when does UG system arise |
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Definition
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Term
| stages of kidney development |
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Definition
| pronephros, mesonephros (functional interim kidney at end of week 4), metanephros (develops from ureteric bud, functional by week 9) |
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Term
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Definition
| outgrowth of mesonephric duct and metanephric mesoderm |
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Term
| what happens to pronephric duct? |
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Definition
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Term
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Definition
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