Term
|
Definition
prevent release of transmitter; stops vesicle fusion
- costmetic, tics |
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Term
|
Definition
Mimics ACh at M receptors
- helps urination |
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Term
|
Definition
Mimics ACh at N receptors (direct cholinergic agonist)
- Smoking cessation |
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Term
|
Definition
direct cholinergic agonist
- eye drops for glaucoma |
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|
Term
|
Definition
partial agonist,
Ocusert: glaucoma OR Salagen : Sjogren's dry mouth |
|
|
Term
|
Definition
| M3 agonist, treat Sjogren's: Side effect is dry mouth |
|
|
Term
| Pyridostigmine (Mestinon) |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
M3 agonist causing the muscle to contract and engage in miosis, letting aqueous humor leave
- Glaucoma |
|
|
Term
| Demecarium Bromide (Humorsol) |
|
Definition
|
|
Term
|
Definition
| Direct antispasmodic effect on smooth muscle & ACh inhibition on smooth muscle - urinary incontinence |
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|
Term
|
Definition
| competitive antagonist on bladder muscle (less ACh) |
|
|
Term
|
Definition
blocks postsynaptic M receptor (Bind to the receptor and prevents ACh from binding) DIRECT
- Organophosphate antidote |
|
|
Term
|
Definition
regenerates AChE INDIRECT
- Organophosphate antidote |
|
|
Term
|
Definition
ACh down
Hyperhidrosis: excessive sweating |
|
|
Term
| Procyclidine HCl (Kemadrin) |
|
Definition
| anticholinergic, only stage 1& 2 for tremors or for drug induced PD |
|
|
Term
|
Definition
| anticholinergic, only stage 1& 2 for tremors or for drug induced PD |
|
|
Term
|
Definition
AChEI for Alzheimer's
- NVD, drool, muscle cramps, allergic rxns, loss of appetite, tired, trouble sleeping |
|
|
Term
|
Definition
AChEI for Alzheimer's
- NVD, drool, muscle cramps, allergic rxns, loss of appetite, tired, trouble sleeping |
|
|
Term
|
Definition
AChEI for Alzheimer's
- NVD, drool, muscle cramps, allergic rxns, loss of appetite, tired, trouble sleeping |
|
|
Term
|
Definition
NMDA (Glutamate) receptor antagonist
- extreme tiredness, dizziness, confusion, headache, constipation, vomiting, pain (especially back), coughing, shortness of breath, hallucination (high dose required) |
|
|
Term
|
Definition
| increase DA synthesis, ↑DA |
|
|
Term
|
Definition
| stimulate release of DA, ↑DA |
|
|
Term
|
Definition
| inhibit MAOB in the synapse & presynaptic cell, ↑DA |
|
|
Term
|
Definition
| Inhibit COMT in synapse (metabolizing DA), ↑DA |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| prevents COMT in periphery (metabolizing l-dopa), ↑DA |
|
|
Term
|
Definition
| prevents L-dopa conversion in the gut,(peripheral LAAD) (less side effects, lower L-dopa dose needed) ↑DA |
|
|
Term
|
Definition
|
|
Term
|
Definition
- L-dopa (precurser to DA)
- Carbidopa (prevents L-dopa conversion in the gut)
- Entacapone (prevents COMT in periphery) |
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