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#3 Respiratory Tract Infections 1
N/A
27
Microbiology
Graduate
08/17/2012

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Term
Respiratory tract infections can be classified on the basis of what?
Definition
Anatomical position (upper, middle, and lower)
Term
What causative agents can cause upper respiratory tract infections?
Definition
Rhinitis, pharyngitis, tonsilitis, peritonsillar or retropharyngeal abcesses
Term
What are some clinical features of Rhinitis?
Definition
Fever, inflammatory edema of nasal mucos, increaed mucus, nasal obstruction
Term
What are some clinical features of pharyngitis and tonsilitis?
Definition
Sore throat, red/swollen pharynx, exudates and petechial hemorhagic spots, vesicles and ulcers, pseudomembranes, enlarged/tender cervical lymph nodes
Term
What are the clinical features of stomatitis (inflammation of oral cavity)
Definition
Multiple ulcers on oral mucosa extending to tongue lipes and face, oral thrus in candidiasis
Term
What are the clinical features of aphthous stomatitis?
Definition
Single or multiple painful ulcers with irregular margin in the oral cavity, often confused with herpes, recurs in relation to stress
Term
What are the clinical features of Noma or Cancrum oris?
Definition
Severe gangrenous stomatitis progressing beyond the mucus membrane to involve soft tissue, skin, and sometimes bone, seen in patients with poor oral hygiene and malnurished children
Term
What are the clinical features of peritonsillar and retrotonsillar abscesses?
Definition
Local pain, fever, tonsillar asymmetry, commin in children above 5 and adults, arises as a complication of tonsillitis
Term
What are the clinical features of retropharyngeal or lateral pharyngeal abscesses?
Definition
Occurs in children under 5, arises as a complication of pharyngitis or accidental perforation of the pharyngeal wall, pain, difficulty swallowing, change in phonation, extended neck, anterior bulging of pharyngeal wall, x-ray shows widening of space between cervical spine and posterior pharyngeal wall
Term
What are the clinical findings for epiglottitis (middle respiratory tract)?
Definition
Through and neck pain, fever, inspiratory stridor, muffled phonation, difficulty swallowing, acute airway obstruction may cause death
Term
What are the clinical findings for laryngitis and croup(middle respiratory tract)?
Definition
Localized to subglottic laryngeal structures including vocal cords, may sometimes extend to trachea and bronchus, fever, inspirator stridor, hoarse phonation, harsh cough, chest pain, aphonia
Term
What are the clinical findings for chronic bronchitis (middle respiratory tract)?
Definition
Long standing damage to the bronchial epithelium due to chronic smoking, chronic infection, or chronic lung disease, patients lack functional integrity, susceptible to infections, recurrent infections
Term
How do you diagnostically test for epiglottitis?
Definition
Bacterial, isolate organism from nasopharynx or pharynx in blood culture
Term
How is laryngotracheitis or laryngotracheobronhitis diagnostically approached?
Definition
Bacterial infection is rare but demands immediate attention, gram-staining and culture of sputum or of specimens obtained by direct laryngoscopy, blood culture
Term
What are the diagnostic characteristics of acute bronchitis?
Definition
B. pertusis is major bacteriologic consideration, specimens should be plated on appropriate media, gram staining and direct flourescent antibody techniques
Term
What is the general cause of lower respiratory tract infection?
Definition
Develops with invasion and disease of the lung, including the alveolar spaces, and their supporting structures, the interstitium, and the terminal bronchioles, may result from extension of MRTI, aspiration of pathogens, and hematogenous spread from a distant site such as an abscess or infected heart valve
Term
What are the clinical findings of acute pneumonia (lower respiratory tract infection)?
Definition
Malaise, fever, chill, cough, production of purulent sputum, dyspnea, rapid breathing, cyanosis, chest pain
Term
What are the clinical findings of pleural effusion (lower respiratory tract infection)?
Definition
Refers to transudation of fluid into the pleural space in response to an inflammatory process in adjacent lung parencyma, may result from infectious and non-infectious causes
Term
What are the clinical findings of empyema (lower respiratory tract infection)?
Definition
Refers to a purulent infection of the pleural space that develops by contiguous spread from an infected lung through a bronchopleural fistula or by extension of abdominal infection through the diaphragm
Term
What are the clinical findings of lung abscesses (lower respiratory tract infection)?
Definition
Usually arises as a complication of acute or chronic pneumonia, symptoms include fever, cough, and foul smelling sputum
Term
Establishment of etiological diagnosis of LRTI depends on what?
Definition
Number of organisms produced in respiratory secretions, whether the causative species is normally found in oropharyngeal flora, and how easily it is grown on culture media
Term
Why is sputum commonly examined for causative agents of LRTIs?
Definition
Easy and non invasive, though contamination of the specimen with oropharyngeal flora is a risk, shows an abundance of inflammatory cells and no squamous epithelial cells
Term
What is the cornerstone of diagnosis of respiratory tract infections?
Definition
Culture of the appropriately collected specimen, radiology helps to confirm diagnosis
Term
Patchy infiltrates related to multiple foci centering on small bronchi in images suggests what?
Definition
Bronchopneumonia
Term
Uniform consolidation of one or more lobes in images suggests what?
Definition
Lobar penumonia
Term
Diffuse interstitial pattern in images suggests what?
Definition
Viral pneumonia or PCP in immunocompromised hosts
Term
Surgical measures are often needed as adjuncts to antimicrobial therapy in what?
Definition
Chronic pneumonia, lung abscess, empyema
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