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2nd GP exam
skeletal & muscular
60
Physiology
11th Grade
11/11/2008

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Term
function of skeletal muscle (4)
Definition
-produces movement to help us survive.
-maintains posture
-supports soft tissue
-makes breathing, digestion, circulation, & waste elimination possible
-makes heat to maintain body temp
Term
epimysium
Definition
covers the outside of muscle
Term
sarcomere (5)
Definition
-shortens when muscles contract
-between 2 Zlines
-functional unit of the skeletal muscle system
-2 actin filaments overlap a thicker myosin filament
-cross bridges of the myosin filament bind with the action filament & z lines move toward one another causing a contraction
Term
muscle cell structure
Definition
muscle -- fasciculus -- cells -- myofibrils -- myofilaments (actin & myosin)
Term
Z line (2)
Definition
-middle of the I band. contains actin vinding proteins
-defines the sarcomere
Term
M line
Definition
composed of protein and connects the centers of the myosin filaments
Term
I bands
Definition
composed of actin filaments
Term
A bands
Definition
composed of myosin filaments
Term
mechanism of muscle contraction (12)
Definition
-myofibril shortens with actin & myson slide over each other
-the length of these filaments do not change
-z lines move toeward each other as actin & myosin slide toward the center of the sarcomere
-then the sarcomere shortens
-when a series of sarcomeres shorten, the whole muscle shortens, & the muscle contracts
-sliding actin between the myosin & actin is accomplished when knoblike projections of the myosin filament bind with the actin filament
-ATP provides the energy to make cross bridges move
- muscles contract when CA are released from the sarcomere reticulum & relax when the ions are reabsorbded
-each actin molecule has an active site
-the cross bridge of the myosin filament binds when the muscle contracts
-when CA is released into sarcoplasm, troponin shofts towards it, binds to it, & changes shape pulling the tropomyosin off the active site
-myosin cross bridges bind to exposed active site & the muscle contracts
Term
tropomyosin
Definition
covers the active site
Term
troponin
Definition
holds the tropomyosins in place
Term
neuromuscular junction (4)
Definition
-nerve cells that stimulate muscle fibers are called motor neurons
-motor neurons extend into muscles through many fine branches
-where neuran & muscle meet is called a meuromuscular junction
-the neuron fiber & muscle fiber together are called a motor unit
Term
isotonic
Definition
flex
Term
isometric
Definition
point
Term
the muscles--facial (epicranius, orbiculuaris occuli, orbicularis oris, masseter)
Definition
epicranius--surprise or horror
orbiculuaris occuli--winking & blinking
orbicularis oris--controls our lips
masseter--chewing capabilities
Term
diseases of the muscles--pulled tendon
Definition
where the muscle/tendon connetion is partially or completely separated from the bone. may require surgery.
Term
diseases of the muscles--contusions
Definition
where a blood vessel breaks within a muscle causing a bruise
Term
diseases of the muscles--hernia
Definition
a tear or rupture in the muscle allowing an organ or blood vessel to protrude through the muscle wall
Term
the muscles--neck
Definition
big one--sternocleidomastoid
the 2 stern.'s on the side of the neck enable neck movement
Term
the muscles--abdominal(rectus abdominus, external oblique)
Definition
rectus abdominus--supports internal organs & flexes trunk.
external oblique--compresses abdomen & rotates & flexes the vertebral column
Term
the muscles--pectoralis major
Definition
chest muscle, adducts & rotates supper arm
Term
the muscles--trapezius
Definition
lowel neck, supper back, raises shoulder
Term
the muscles--deltoid
Definition
shoulder, abducts arm
Term
the muscles--arm (biceps & triceps & brachloradialis)
Definition
biceps--upper arm, flexes & rotates arm outward
triceps--upper arm. extends arm
brachloradialis--major muscle of forearm. flexes forearm
Term
the muscles--gluteus maximus
Definition
BUTT
Term
quadriceps (4 muscles)
Definition
rectus femoris
vastus lateralis
vastus medialis
vastus intermedius
Term
the muscles--gastrocnemius
Definition
flexes lower leg & extends foot
Term
the muscles--soleus
Definition
extends foot
Term
blood functions (5)
Definition
-transports gases, nutrients, hormones, & metabolic waste
-regulares pH (potential of H)
-stabilizes body temp
-contains enzymes/proteins to repair vessel damage
-carries white blood cells to defend against pathogens & toxins
Term
RBC anatomy
Definition
--have no nucleus
-their constant movement through vessels cause damage
-they do not have mitochondira or ribosomes, & cannot carry out repairs. short lived.
-- are made by stem cells in bone marrow
--shape increases it's O2 carrying capacity
--transports O2 by means of hemoglobin
Term
hemoglobin
Definition
--hemoglobin is a complex protein composed of 4 polypettide chains
--each hemo group = iron atoms that atrract O2
--the hemoglobin molecule readily combines with O2 to form oxyhemoglobin
--this gives blood it's red color
Term
blood composition (plasma, platelets, blood cells)
Definition
plasma = 90% water.
7% blood proteins
(albummin--regulates osmotic conditions of the blood
globulin--transports lipis such as cholesetrol & fat. soluable vitamins.
fibrinogen=-a protein essential for blood clotting.)
3% gases, ions, hormones, & variuos nutrients
Term
platelets
Definition
--also called thrombocytes
--small colorless disc shaped fragments formed from cytoplasm of WBCs
--produced in the bone marrrow
--clotting consists of several steps when a blood vessel is cut or damaged
--platelets help the clotting process. platelets plug the hole.
--damaged tissue releases a lipoprotein called tissue factor
--tissue combines with thromboplastin
--fibrinogen is converted to fibrin
--chemical reactions end with a scab/clot
needs CA & vitK
Term
blood clotting
Definition
--smooth muscle constricts to reduce blood flow
--platelets clot hole
--serotonin constricts the vessels
--coagulation phase, fibrinogen converted to fibrin
--fibrin forms clot, pulling wound together to stop bleeding
--tissue may now repair itself
Term
blood clot disorders-- hemophilia, heart attack, stroke, thrombus, embolism, thrombocytopenia, thrombocytosis
Definition
hemophilia--genetic disorder of clotting factors
--clot on brain---stroke
--clot on heart: heart attack
--traveling clot: embolism
--thrombus:blood clot on a vessel wall
thrombocytopenia: too few platelets: intestinal bleeding
excess platelets: may be an indication of infraction, inflammation, or cancer.
Term
erythropoesis (5)
Definition
formation of red blood cells
--formed with kidneys detection drop in RBC count (lack of O2)
--kidneys release EPO
--EPO enters bloodstream & activates hemotocytoblasts (bone marrow)
--then iniations production of more RBS
--RBS last 120 days
health person= 65 million/sec
Term
white blood cells (leukocytes)
Definition
--5 major types (neutrophils, eosinophils, basophils, lymphocytes, monocytes)
--distinguished by size & staining properties
--produced by stem cells in bone marrow
--retains their nuclues

--normal ratio RBC to WBC: 500:1
WBC count should be about 5000mm3

counts below this indicate damage to marrow cells
--counts of 10,000 mm3 indicate infection
--counts of 100,000mm3 is a symptom of leukemia
Term
white blood cells (neutrophils, basophils, eosinophils, monocytes lymphocytes)
Definition
neutrophils--most nuermous WBC; functions by engulfing & invading microorganisms ( bacteria) phagocytosis
basophils--involved in release of hepasin, histamine & seratonin @ infection sites to prevent clotting and initiate inflammation response
eosinophils--involvedin inflammatory response, eso from parasitic infection
lymphocytes--produced in lymph & bone tissue, released antibodyes to fight pathogens & toxins, may survive for years.
monocytes --activated @ infection site. chnage to macraophage & functions as neurophil to attack compounds pound to antibodies.
Term
vitK (2)
Definition
--bacteria in gut & veggies
--coenzymes that speed up metabolic processes
Term
formed elements
Definition
Term
sarcoplasmic reticulum
Definition
Term
plasma proteins
Definition
Term
perimysium
Definition
each fasciculus is wrapped in a fibrous sheath called perimysium
Term
endomysium
Definition
thin covering of each muscle fiber
Term
tendon
Definition
muscle to bone
Term
ligament
Definition
bone to bone
Term
myosin/actin
Definition
myson-thick
actin-thin
proteins
Term
active site
Definition
each actin has one. crossbridge of the mysoin filaments bind when muscle contracts
Term
origin/insertion
Definition
origin--point of attachment on immoveable bone
insertion--point of attachment on moveable bone
Term
formed elements
Definition
blood = plasma, RBC, WBC, & platelets
Term
pulmonary circulation
Definition
pumps blood to the lungs
25/8 blood pressure (right)
Term
Systemic circulation
Definition
pumps blood to the body
120/80 blood pressure (left side)
Term
cardiac cycle *
Definition
-- atria are relaxed & blood enters them through venous pressure . the atria then contracts weakly & forces blood into ventricles
-- ventricles contract & force blood out of heart. into arteries
Term
systole & disastole
Definition
systole -- contraction of heart muscle
disastole--relaxation of heart muscle

disastole -- 800mm Hg
Term
anatomy of the heart (9)
Definition
--muscle about the size of 1-2 fists
--pericardium:covers the heart
--myoardium: composed of cardiac muscle. forced to pump blood
--endocardium: made up same stuff as blood & lymphs
--septum separates right & left halves
--heart is furthur divided into upper & lower chambers
--upper chamber: atrium: receives blood from veins
--lower chamber: ventricle pumps blood to arteries going to lungs or body
Term
heart valves (6)
Definition
--membranous valves separate the 4 chambers of the heart
-they regular blood flow
--atroventricular valves separate the atria & ventricles
--simillunar valves separate tyhe heart from the vessels that lead to & away from it
--valves open only in direction of bloodflow & prevent back flow
--they are regulared by the pressure on either side
Term
atrioventricular valves (6)
Definition
--2 atrioventricular valves each with specific structures
--the tricuspid valve is comprised of 3 casps ( parts) & separates the right atrium from the right ventricle
--the bicuspid valve has 2 cusps & separates the left atrium from the legft ventricle
--as the atria contract, blood is forced from the atria through the tricuspid & bicuspid valves to the ventricle
--papillary muscles & chardea tendinea prevents valves from evertiring
Term
semilunar valves (5)
Definition
--called semilunar because of their shape
--they separate the heart from the vessels leading away from it
--the pulmonary semilunar valve is a one-way valve located in the pulmonary artery which carries blood from the heart to the lungs
--the aorta semilnunar valve is located in the aorta which carries blood from the heart to the rest of the body
Term
SA node
Definition
--sinatrial node & controls heartbeat
--located in the wall of the right atrium "pacemaker"
--capable of independent depolarization
--causes the atria muscles to contract
--delay in signal transmission: heart beat
--
Term
AV node
Definition
--atrioventricular node. stimulates the ventricles to contract simultaneously
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