Term
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Definition
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this is where filtration takes place; this consists of glomerular capsule (Bowman's capsule) and enclosed glomerulus
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Term
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Definition
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these cells, located on the visceral layer of the glomerular capsule, cling to the glomerulus capillaries; highly modified branching cells
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Term
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Definition
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descending and ascending loop of Henle
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Term
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Definition
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nephrons that are located entirely in cortex
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Term
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Definition
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these nephrons' loop of Henle go deep into medulla; produce concentrated urine
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Term
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Definition
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these capillaries cling closely to renal tubules and absorb solutes and water from the tubule cells
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Term
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Definition
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the peritubular capillaries of juxtamedullary nephrons; they extend deep into medulla paralleling the longest loops of Henle
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Term
| juxtaglomerular apparatus |
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Definition
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this is the most distal portion of ascending limb of loop of Henle; this lies against the afferent arteriole feeding the glomerulus
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Term
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Definition
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these muscle cells act as mechanoreceptors that sense blood pressure in afferent arterioles
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Term
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Definition
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chemoreceptors that that respond to changes in NaCl content; this and granular cells play important roles in regulating rate of filtrate formation
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Term
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Definition
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this membrane lies between blood and interior of glomerular capsule
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Term
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Definition
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this pressure is responsible for filtrate formation
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Term
| glomerular hydrostatic pressure |
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Definition
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force pushing water and solutes out of blood and across filtration membrane
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Term
| colloid osmotic pressure of glomerular blood and capsular hydrostatic pressure |
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Definition
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two filtration - opposing forces
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Term
| glomerular filtration rate |
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Definition
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volume of filtrate formed each minute by combined activity of all 2 million glomeruli of kidneys
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Term
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Definition
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part of renal autoregulation (intrinisc control); tendency of vascular smooth muscle to contract when stretched; increasing systemic BP causes afferent arteries to constrict which restricts flow into glomerulus; opposite when low BP
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Term
| tubuloglomerular feedback |
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Definition
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(intrinsic control); directed by macula densa cells of juxtaglomerular apparatus; these cells, located on walls of ascending limb of Henle's loop, respond to filtrate concentration NaCl concentration
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Term
| sympathetic nervous system control |
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Definition
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extrinsic control of filtration; during stress; neural controls constrict afferent arterioles inhibiting filtrate; this in turn trips the renin-angiotensin mechanism by stimulating macula densa
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Term
| renin-angiotensin mechanism |
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Definition
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triggered when various stimuli cause granular cells to release renin which enzymatically acts on angiotensinogen converts it to angiotensin I. this turns into angiotensin II by ACE; angiotensin II stabilizes systemic BP
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