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Title: 2 week of development

Description: 2nd week of Human Development

Total Flash Cards: 20

Created: 01/21/2009 15:38:55

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Term
Cytotrophoblast
Definition
mononucleated layer of cells that is mitotically active forms new trophoblast cells that migrate into increasing mass of syncytiotrophoblast where they fuse and lose their cell membranes
Term
Syncytiotrophoblast
Definition
a rapidly expanding, multinucleated mass in which no cell has boundaries. produces hCG which maintains corpus luteum
Term
Hcg functions
Definition
produced by syncytiotrophoblast and enters maternal blood in lacunae. maintains activity of corpus luteum in ovary. Basis of pregnancy test
Term
Exocoelomic Membrane
Definition
becomes the primary yolk sac
Term
Yolk Sac
Definition
extraembryonic mesoderm increases and isolated spaces appear within it which fuse to form a large cavity called extraembryonic coelom.
Term
Lacunae
Definition
appear in syncytiotrophoblast.filled with mixture of maternal blood from endometrial capillaries and secretions from eroded uterine glands.
Term
Corpus Luteum
Definition
secretes estrogen and progesterone to maintain the pregnancy
Term
Uteroplacental Circulation
Definition
when maternal blood flows into lacunae, oxygen and nutritive substances become available to the embryo.
Term
Decidual Reaction
Definition
endometrial connective tissue undergo transformation by accumulating glycogne and lipid in the cytoplasm...allows immunological privilege to conceptus
Term
Human Chorionic Gonadotropin
Definition
57,000 MW with alpha beta subunits produced by syncytiotrophoblast. enters maternal blood circulation. prevents degeneration of corpus luteum.
Term
Oncofetal Antigens
Definition
cell surface antigens that normally appear only on embryonic cells but also express themselves in human malignant cells.
Term
Carcinoembryonic Antigen
Definition
glycoprotein involved in cell adhesion. Normally producedduring fetal development, butproduction stops before birth. used to determine recurrences of carcinomas after surgery
Term
Alpha-fetoprotein
Definition
produced by liver and yolk sac. high levels may indicate and abnormal development. may be produced by some tumors as well.
Term
RU-486
Definition
induces abortion if taken during first 3 months of pregnancy. blocks the action of progesterone. usually taken with prostaglandin.
Term
Placenta Previa
Definition
causes vaginal bleeding (antepartum haemorrhage) placenta implants over the cervix
Term
Risk of Placenta Previa
Definition
Previous placenta previa, caesarean delivery, or abortion. -Women who are younger than 20 are at higher risk and women older than 30 are at increasing risk as they get older. -Women with a large placentae from twins. -Women who smoke or use cocaine may be at higher risk.
Term
Inhibition of Implantation
Definition
estrogens can prevent implantation of blastocyst but not fertilization. *Diethylstilbestrol
Term
IUD intrauterine device
Definition
inside uterus through vagina and cervix interferes with implantation causing inflammatory reaction. some have progesterone.
Term
Placenta as allograft
Definition
protection of conceptus involves down-regulation of MHC class I antigen expression on trophoblast. immunosuppresive environment of uterus.
Term
Decidual cell protection of conceptus
Definition
produce locally active immunosuppressor molecules like prostaglandins E2 which prevent activationof the cells and NK cells within decidua.



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