| Term 
 | Definition 
 
        | 1) Protection: Physical and chemical barrier to outside elements 2) Form: smooths out surface of layers deep to it 3) Maintain Hydration: Helps keep water in system 4) Temperature Regulation: heating/ cooling 5) Vitamin D Production 6) Detection of Stimuli 7) Blood Reservoir: Blood can be diverted away from skin to go to other organs 8) Excretion: removal of waste & water (sweat) |  | 
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        | Term 
 | Definition 
 
        | Epidermis: thin layer; most superficial; thick keratinized squamous epithelium; 4 cell types; 4-5 layers Dermis: thick, 2nd(deep)layer; Strong connective tissue; bound together with fibers; matrix synthesized by fibroblasts
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        | Term 
 | Definition 
 
        | 1)Keratinocytes: most numerous; backbone; deep layer is mitotic 2)Melanocyte: Basal layer of epidermis; makes melanin- once synthesized, melanin sent from melanocyte to kerotinoctyes (protects kerotinocytes from UV rays)
 3)Langerhan's Cells: dendridic cell; manufactured in bone marrow
 4)Merkel Cells: sensory receptor cells; associated with nerve ends
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        | Term 
 
        | Layers of Epidermis (deepest to superficial) |  | Definition 
 
        | 1)Statum Basale (germinativum): bottom/deepest/youngest layer; single cell; mitotic 2)Statum Spinosum: spiny projections because cells retract
 3)Statum Granulosum: flattened with modified keratin which forms granules which contain waterproofing glycolipid (keeps water from penetrating into body); last cells to be nourished by blood by diffusion; last layer of living cell
 4)Statum Lucidum: only present in thick skin (palms/soles of feet)
 5)Statum Corneum: thickened plasma membranes; protects deeper cells; cornified; desquamation(part that flakes off); 20-30 cell layers thick
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        | Term 
 | Definition 
 
        | 1)Papillary layer: thin, superficial layer of connective tissue; many blood vessels, projections and indentations, and dermal ridges
 2)Reticular layer: deeper and much thicker; bundles of collagen fibers; dense irregular connective tissue; collagen gives strength and binds water; elastin gives recoil properties; striae=collagen tearing
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        | Term 
 | Definition 
 
        | 1) Melanin: protein responsible for yellow, red, tan, and black; made in melanocytes; accounts for racial differences; Freckles/moles-concentration of melanin 2) Carotene: yellowish; from eating yellow vegetables/egg yolks 3) Hemoglobin: blood/redness; give you healthy look |  | 
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        | Term 
 | Definition 
 
        | Appendage of the skin; layers of dead keratinocytes -primarily hard keratin
 -shaft projects from skin
 -Root imbedded in skin; not visible
 -color determined by melanoctyes at base of follicle;
 -Hair follicle extends deep to dermis and hypodermis
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        | Term 
 | Definition 
 
        | Appendages of the skin; modification of existing epidermis -Hard keratin:(like statum corneum);for protection and grip on dorsal side
 -Nail matrix(like statum germinativum of epidermis); where keratinocytes reside to generate the nail
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        | Term 
 | Definition 
 
        | Appendages of the skin 
Sweat: function is temp regulation; Sebacious:(oil glands); outgrowths of hair follicles; secrete sebum (oily lipid); Hormonal stimulation at puberty (clogged duct causes infection/acne) |  | 
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        | Term 
 
        | Hair Shaft (shape and layers) |  | Definition 
 
        | -Shaft Shape equals the shape of hair; flat=curly, oval=wavy, Round=straight 
 Layers:
 1)Medulla: innermost, bulky layer of flattened cells, softer keratin
 2)Cortex: middle layer
 3)Cuticle: outermost; single layer of keratinoocytes (arranged like shingles); maintains integrity of hair shaft and keeps shafts separate
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        | Term 
 | Definition 
 
        | 1)Hair Bulb: contains statum germinativum (mitotic kerotinocytes); push up and outward to form hair layers 2)Root Hair Plexus: nerve/sensation 3)Papillae: blood supply to statum germinativum;  melanocytes sit on top 4)Arrector Pili Muscle: attached to hair shaft; contracts when scared/cold; causes dimpling of overlying skin |  | 
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        | Term 
 | Definition 
 
        | 1) Eccrine (merocrine): coiled, tubular gland open on much of body but concentrated on skin of palms, forehead, and soles of feet; ultrafilate of blood controlled by C.N.S 2) Apocrine: also merocrine but located in axillary regions; larger than eccrine; ducts empty into hair follicles (deeper in dermis/hypodermis); sweat, fat and protein but odorless (bacteria causes odor); begins functioning at puberty (not involved in temp regulation- just scared or exercising? 3) Ceruminous: wax producing gland in external ear canal; protects/keeps ear clean 4) Mammary: secretes milk |  | 
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