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White Blood Cells
white blood cells/leukocytes
56
Veterinary Medicine
Undergraduate 2
01/13/2012

Additional Veterinary Medicine Flashcards

 


 

Cards

Term
the normal amount of lobes in a neutrophil
Definition
2-5
Term
what is PMN
Definition
polymorphnuclear
Term
the color of the cytoplasm of a neutrophil
Definition
  • colorless
  • pale pink
  • faintly basophilic
Term
the granules of a neutrophil stain?
Definition
  • may not stain
  • may be light pink
Term
how many lobes are in eosinophil
Definition
often 2
Term
why might the nucleus of an eosinophil be obscurred in a horse?
Definition
the granuals are so huge and redish pink
Term
what color is the cytoplasm of an eosinophil
Definition
faint blue (basophilic)
Term
what breed of dog has vacuoles in the cytoplasm of their eosinophils?
Definition
greyhound
Term
which animal has rod shaped granules in their eosinophils?
Definition
cat
Term
what color is the cytoplasm in basophil
Definition
generally pale blue (basophilic)
Term
canine basophil granules
Definition
  • purple
  • not numerous
  • degranulated basos-purple cytoplasm with not granules
Term
feline basophil granules
Definition
  • lavender
  • round or oval

 

Term
basophil granules in ruminants, equine, and pigs
Definition
numerous deep purple and often obscures the nucleus
Term
which WBC is the largest of the WBCs
Definition
Monocyte
Term
monocytes and lymphocytes are what kindof leukocytes?
Definition
mononuclear
Term
shapes of the nucleus of monocyte
Definition

kidney bean

band-shaped to almost lobulated

ameoboid

less clumped chromatin than segs

Term
cytoplasm of monocyte
Definition

blue-gray

may contain vacuoles or small pink granules

Term

what is a reason you may see vacuoles in a monocyte

 

Definition
it is phagocytizing
Term
what is N:C ratio mean?
Definition
nucleus to cytoplasm ratio.
Term
nucleus of lymphocyte
Definition

coarsly clumped chromatin

usually round

maybe oval or indented

usually eccentrically placed

Term
color of cytoplasm of lymphocyte
Definition
pale blue
Term
when a lymphocyte is reactive you might be able to see?
Definition
granules
Term
rabbits, rodents, birds, reptiles, amphibians have what instead of neutrophiles
Definition
heterophils
Term
what color are the granules in a heterophil
Definition
red-brown
Term
what is a band neutrophil?
Definition
Immature Neutrophil
Term
what is the term for when band neutrophils are increase in circulation
Definition
A left shift
Term
what is a common cause for a left shift?
Definition
inflammation
Term
what is an average amount of WBCs that should be seen per LOW power field?
Definition
20-50
Term
when doing a WBC differential why would you want to look at the feather edge first?
Definition
check for clumping, parasites, check for alot of WBCs
Term
when doing an actual count of WBC what objective are you doing the count under?
Definition
oil aka. 1000x
Term
how many nRBCs do you have to see before you perform a corrected WBC count?
Definition
>5 nRBCs per 100 WBCs
Term
Pelger-huët anomaly?
Definition

Hyposegmentation of ALL granulocytic nuclei

all granulocytes nucleus looks like a band

 

Term
what causes a neutrophil to become hypersegmented?
Definition
glucocrticoids could cause this but the most common reason is because its just an "old" neutrophil that has been in circulation for a long time
Term
with Birman cat neutrophil granulation anomaly what color are the granules?
Definition
fine red brown granules
Term
true or false? birman cat neutrophil granulation anomaly causes major problems in the cat?
Definition
false- doesnt cause a problem, its an incidental finding.
Term
Chediak-higashi syndrom affects which animals?
Definition
cattle and cats
Term
what causes chediak-higashi syndrom?
Definition
its inherited/congenital
Term

 3 toxic neutrophil changes

 

Definition

Dohle bodies
foamy cytoplasm(cytoplasmic vacuolization)

toxic granulation (intensely stained primary granules)

Term
döhle bodies can be found in healthy animals in small numbers, which animals are they?
Definition
feline and equine
Term
which has the more severe toxic change? döhle bodies or foamy cytoplasm?
Definition
foamy cytoplasm
Term
-cytosis
Definition
increase in monocytes or lymphocytes
Term
-penia
Definition
decreased # of any of the cells
Term
-philia
Definition
Increased # of any of the granulocytes
Term
Leukemia
Definition
a malignant increase in WBC
Term
Karyolysis
Definition
nuclear lysis of neutrophil (usually seen in joint fluid not circulation)
Term
Pyknosis
Definition
compaction of neutrophil with condensed, dense nuclear material (usually not in blood sample, seen in joint fluid)
Term
Karyorrhexis
Definition
fragmentation of nucleus (not usually seen in circulation, found in joint fluid)
Term
cause of reactive lyphocytes
Definition
antigenic stimulation (disease, exposed to disease, vaccinated recently)
Term
reactive lymphocyte looks like
Definition
increased basophilia in cytoplasm- dark purple
may have a more abundant cytoplasm
Term
how should a WBC count be expressed (examples)
Definition

17.2 X 10^3/μL
17.2 K/μL

17,200 cells/μL

Term
1 μL = how many mm?
Definition
1mm^3

1mmX1mmX1mm
Term
[image]
Definition
birman cat neutrophil granulation anomaly
Term
[image]
Definition
Reactive lyphocyte
Term
[image]
Definition
Hypersegmentation
Term
[image]
Definition
dohle body
Term
[image]
Definition
chediak-higashi syndrom
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