Term
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Definition
| Study on how drugs move into through and out the body |
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Term
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Definition
| Study of how drugs produce their effects within the body |
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Term
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Definition
| Ideal range of drug concentration within the body |
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Term
| 3 componets of te therapectic admin of drugs |
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Definition
1 dose- amount given at one time
2 dosage interval- time between admin
3 route of admin- Parenteral(IM,IV,SQ,IP,IN,IO,ID,IC)
PO Topical |
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Term
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Definition
1 Absorption
2 Distribution
3 Metabolism
4 Elimination/Excretion |
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Term
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Definition
| Movement of drug from the site admin to systemic circulation |
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Term
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Definition
| How much of the drug is actually absorbed |
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Term
| Factors which may affect absorption |
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Definition
1) Ph
2) Drug form
3) GI motility
4) First-Pass effect
5) Pefusion |
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Term
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Definition
| Drug from systemic circ to/into tissues. |
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Term
| Natural barriers to distribution |
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Definition
-BBB
-prostate
-Eye
-Synovivm |
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Term
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Definition
1-Liver->Bile->Feces
2-kindeys->urine |
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Term
| What are the 2 types of neurons in the ANS |
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Definition
1) pre-ganglionic/synaptic
2) post-ganlionoc/synaptic |
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Term
| what is the sympathetic system called |
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Definition
Adrenergic
Fight or flight |
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Term
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Definition
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Term
| In the sympathetic system pre-ganglionic fiber are |
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Definition
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Term
| In the sympathetic system post-ganglionic |
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Definition
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Term
| In the sympathetic system post-ganglionic |
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Definition
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Term
| Sympathetic system post-ganglionic neurotransmitters are |
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Definition
| norepinephrine, eponephrine, and dopamine |
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Term
| Sympathetic system receptors are |
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Definition
| Alpha, Beta, Dopaminergic |
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Term
| Parasympathetic system Pre and post ganglionic neurotransmitter is |
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Definition
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Term
| Parasympathetic system receptors are |
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Definition
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Term
| Parasympathetic system is also called |
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Definition
Cholinergic
Rest and repose |
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Term
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Definition
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Term
| Parasympathetic system pre-gandlionic fibers are |
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Definition
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Term
| Parasympathetic system post-ganglionic fiber are |
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Definition
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Term
| All pre-ganglionic fibers release? |
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Definition
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Term
| The Pre-ganglionic fibers release Ach in to what receptors |
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Definition
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Term
| What are the 2 types or ach receptors |
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Definition
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Term
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Definition
| A knot- like newtwork of nerve cell bodies outside the CNS |
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Term
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Definition
| Chemicals by which neurons communicate |
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Term
| Adrenergic neurotransmitters |
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Definition
| norepinephrine, eponephrine, and dopamine |
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Term
| Cholinergic neurotransmitter |
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Definition
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Term
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Definition
| Cause excitation or increased activity of their target organ. |
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Term
| Alpha receptors are primarily activated by |
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Definition
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Term
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Definition
causde relaxation or decreased activity of their target organ
-Heart muscle |
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Term
| Beta is activated primarily by |
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Definition
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Term
| Nicotine receptor is stimulated by |
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Definition
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Term
| Muscarinic receptor is stimulated by |
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Definition
| muscarine and parasympathominetic drugs |
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Term
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Definition
| Vasodilation od vessels in kidneys, Heart, and GI tract |
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Term
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Definition
| heart: increased rate, contractility, conduction velocity |
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Term
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Definition
-Arterioies/Veins: vasodilation
-Trachea/bronchioles: relaxation |
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Term
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Definition
| Pre-anesthetic to decrease secretion and prevent bradycardia |
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Term
| Atropine helps with what type of exam. And does what |
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Definition
| ophtho. dilate pupils and decrease ciliary spasm |
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Term
| Glycopyrrolate is/ But doesnt |
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Definition
Similar to atropine
Doesnt cross the CNS |
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Term
| Glycoprrolate is used on what animal |
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Definition
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Term
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Definition
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Term
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Definition
| reactivates acetylchlionesterase to treat OP toxicity |
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Term
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Definition
| diarrhea, uninary incomtinence |
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Term
| Sympathomimetic drugs uses |
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Definition
-Stimulate the heart during cardiac arrest
-Correct hypotenson(vasoconstriction)
-Reverse bronchoconstriction during anaphylactic shock
-allergic reaction
-UTI
-treat glaucoma |
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Term
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Definition
| increses HR/metabolic rate, dilates the bronchioles and blood vessels, |
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Term
| Noreepinephrine (noradrenalin) |
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Definition
Mostly and alpha- agonist with beta effects
-Vasopressor(Raises blood pressure) |
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Term
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Definition
sedative and analgesic
Alpha 2 agonist |
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Term
| reversal agent for Xylazine |
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Definition
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Term
| Phenylpropanolamine (PPA) |
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Definition
| Stimulates both alpha and bata receptors, increses the release of norepinephrine, can treat UTI |
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Term
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Definition
| used for a short-term treatment of heart failure bu increasing contractility and rate |
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Term
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Definition
| causes vasdoilation, decresases seizure threshold |
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Term
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Definition
| hypotensice agent(vasodilator) |
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Term
| Terbutaline and alburterol |
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Definition
bata- agonists
Bronchodilation |
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Term
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Definition
| constricts arterioles in sites other than the brain and kidneys |
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Term
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Definition
| shock, CHF, and inceease renal perfustion |
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Term
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Definition
| dopaminergic and beta 1 receptors |
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