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VT-230 Exotics Week 1
Week 1
64
Veterinary Medicine
Undergraduate 4
05/07/2015

Additional Veterinary Medicine Flashcards

 


 

Cards

Term
30-70%
Definition
Dogs, cats, and primates require what range of humidity?
Term
40-70%
Definition
Rodent rooms require what range of humidity?
Term
45-55%
Definition
Most animal rooms are maintained at what range of humidity?
Term
10-15 air changes
one every 4-6 minutes
Definition
Proper ventilation for animal rooms must have how many air changes per hour?
Term
Recovery cage
Definition
Similar to ICU cages, provides control of temperature, humidity, oxygen pressure etc. IV lines, catheter access ports, and monitoring devices can be incorporated.
Term
Activity cages
Definition
Used to provide exercise for animals, configuration depends on the species being housed. Primates may have jungle gyms or swings. Rodents may have exercise wheels.
Term
Pens and runs
Definition
Primarily used to house dogs, sheep, goats, and farm animals. If outdoors must keep other animals from getting in outdoor enclosures, may cause a loss of dietary control, animal housed outdoors will need to become acclimated to seasonal changes.
Term
Transport cages
Definition
Cages with wheels may incorporate a squeeze section (primates) for temporary housing, does not need food or water sources.
Term
Metabolism cages
Definition
Used to collect urine and feces for measurement and analysis, food and water sources are locates outside of the cage to avoid addition to the waste.
Term
Shoebox cage
Definition
Solid bottomed, usually plastic typically have stainless steel grid top with a feeding station, usually have a filter top to control the micro environment are easily stacked or shelved.
Term
Stainless-steel cages
Definition
Strong, smooth, rust free, chemical resistant, high initial cost, may lower temperatures
Term
Aluminum material cages
Definition
Lightweight, relatively low cost, less durable, may rust, can be damaged by chemicals.
Term
Plastics materials cages
Definition
Lowest initial cost, they have a low to high impact strength, may be heat and chemical resistant, and may be transparent to allow for observation, may be used for disposable cages
Term
Bio safety level IV
Definition
Agents pose a high risk of causing life threatening disease. (Ebola)
Maximum containment procedures are exercised
Shower in/ shower out with full positive pressure body suits.
Personnel must undergo extensive training.
Term
Bio safety level III
Definition
Agents can cause serious and potentially lethal disease.m (mycobacterium, tuberculosis)
Primary and secondary barriers are required to protect personnel
Access must be controlled.
Term
Bio safety level II
Definition
Agents can cause disease in humans if handled incorrectly (toxoplasma, salmonella)
Limited access to the area
PPE must be used
Specific instruction for disposal of contaminated material.
Term
Bio safety level I
Definition
Agents that do not normally cause disease in humans.
These agents may cause disease in immune compromised individuals
No specific handling or disposal requirements for this level.
Term
Micro environment
Definition
This refers to the individual cage, run, pen, where an animal is housed.
Term
Macroenvironemnt
Definition
This refers to the animal housing rooms.
Term
The specific use for that room.
Definition
The air pressure in a room is determined by what?
Term
Negative air pressure
Definition
Means that the air flows from the hall into the room when the door is opened.
ex quarantine
Term
Positive air pressure
Definition
Means the air flows from inside the room to the outside when the door is opened.
ex surgical suites
clean rooms
Term
Thermonuclear zone
Definition
Range of a temperature in which an animal does not not need physical or mechanisms to control heat production or heat loss.
Term
Containment facilities
Definition
Disposable clothing and all materials must be autoclaves, before being passed out of the facility through a special waste portal.
Air passing out of the facility must be treated with heat or filtration to remove infectious organisms.
Usually houses animals with infectious disease.
Term
Barrier facility
Definition
Similair to the layout of double corridor but requires of shower before entering the animal rooms.
Usually required to wear disposable clothing
Entry areas have an airlock
UV light is used to sterilize equipment and supplies.
Usually houses germ free animals.
Term
Intrinsic
Extrinsic
Dietary
Experimental
Definition
The 4 stress factors
Term
Conventional Facility
Definition
Room doors open onto a central corridor
Common in smaller facilities
Cages cleaned in the room, bowls, and supplies cleaned in another to minimize cross-contamination.
Term
Dietary
Definition
Quality and quantity of food and water
Term
Administrator
Definition
Responsible for operations of facility including staff supervision and record maintenance.
Term
Veterinarian
Definition
Usually has training in laboratory animal care specifically also a member of ASLAP, oversees all of the laboratory animal models.
Term
Labratory Animal Tecnologists
Labratory Animal Technicians
Definition
Daily care, ensure all environmental variables are controlled, may also function as research technicians.
Term
Principle Investigator
Definition
Scientist often with an advanced degree, develops hypothesis and interprets data collected.
Term
Animal liberation group
Definition
Animals should not be forced to work or produce for human benefit
Owning a pet is a form of enslavement.
Will break the law and make up information to try and shut down research facilities.
EX: PETA
Term
Animal Welfare Groups
Definition
We should treat animals as kindly as possible and that should be required by law.
The animal is suffering, we should relieve its suffering
Animal shelters mainly belong to this group
Term
Public Health Policy on humane Care and Use of Laboratory animals
PHS
Definition
Agency within US Department of Health and Human Services, addresses the use of euthanasia to relieve pain and suffering in lab animals.
Term
Food and Drug Administration
FDA
Definition
Ensures safety pf the public by enforcing adherence to the guidelines for research on certain products such as medication.
Term
Environmental Protection agency
EPA
Definition
Administers laws to protect human health and the environment.
Term
Animal and Plant Health Inspection Service
APHIS
Definition
Inspects research facilities for violations of AWA yearly.
Term
Regulatory Enforcement and Animal Care Program
REAC
Definition
Enforces penalties for violators of AWA.
Term
United States Department of Agriculture
USDA
Definition
Enforces the AWA, has APHIS and REAC as its main agencies.
Term
Institutional Animal Care and Use Committee
IACUC
Definition
All animal use in research in the U.S must be approved by IACUC on independent entity that cannot be overruled, made up, of a group within the research facility and one community lay person.
Term
Animal Welfare Act
AWA
Definition
First passed in 1966. Governs the sale, transport, and use of animals. Required the formation of IACUC. Requires the PI to consult with the veterinarian to alleviate pain and suffering in animals used.
Term
American College of Laboratory Animal Medicine
ACLAM
Definition
Provides standards of training for veterinarians in this field also performs the certification exam necessary for veterinarians.
Term
National Institute of Health.
NIH
Definition
Provides grants and contracts to support research and training.
Term
Association for Assessment and Accreditation of Laboratory Animal Care
AAALAC
Definition
Provides organization promoting humane treatment if animals in science, membership sought out because it signifies a commitment to excellence. does not make its own regulations.
Term
American Association of Laboratory Animal Science
AALAS
Definition
Formed in 1950. Develops requirements for LAT's, LATG's, and ALAT's.
Term
American Society of Laboratory Animal Practitioners.
Definition
Group of veterinarians with special interest in lab animal medicine.
Term
consumer Product Safety Commission
CPSC
Definition
Enforced regulations in the Federal Hazardous substance Act.
Term
Gnotobiology
Definition
This is the study of animals with completely known flora and fauna.
Term
Conventional animals
Definition
Those animals with unknown microflora used for research.
Term
Defined flora animals
Definition
May be axenic, gnotobiotic, SPF, cesarean derived and barrier sustained animals.
Term
Axenic
Definition
Literally means "without strangers".
These animals are also refereed to as germ-free.
Usually have thinner walled intestines because they have not been exposed to any bacteria.
Term
Gnotobiotic
Definition
These animals have specific microflora. Only the specified microorganisms are present.
Term
Specific pathogen free
Definition
Free of specific pathogens: may have other pathogens
Other then the identified pathogens, the microflora is undefined.
Term
Cesarean derived
Definition
These animals were derived surgically by removal of the mother's uterus and then the fetuses were removed in a sterile isolation chamber.
Term
Barrier sustained or barrier reared
Definition
These animals were delivered by cesarean section and then maintained in a sterile environment. Barrier may be a cage, room, or entire facility.
Term
Sentinel animals
Definition
Animals that are susceptible to a particular pathogen
Term
Reduction
Definition
To use the fewest number of animals possible to achieve a result.
Term
Reduction
Refinement
Replacement
Definition
The 3 R's.
Term
Basic research
Applied research
Clinical research
Definition
The 3 types of research
Term
Basic research
Definition
Concerned with advancing fundamental knowledge of life processes and diseases.
Term
Clinical research
Definition
Builds on the knowledge gained in basic and applied research.
Term
The institution for which the scientist works for
An independent agency
A government agency
Definition
Who can fund research?
Term
Animal exploitation groups
Definition
Generally believe that animals are for the use of human beings and are our absolute property.
Animals don't feel pain as we do
Usually advocates for bull fighting, dog fighting, etc.
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