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Definition
| Species, sex, age, genetics |
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Environmental parameters
(Temperature, etc) |
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| Quality and quantity of food and water |
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Definition
| Surgery, restraint, and drug effects |
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Definition
| Clinical trials on a group of human volunteers before approving the medication |
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Definition
| Group where the variable is manipulated somehow |
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Definition
| No manipulation of the variable |
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Term
| Principal Investigator (PI) |
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Definition
| Scientist, often with an advanced degree, develops hypothesis, plans experimental design, compiles and interprets data collected |
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Term
Laboratory Animal Technicians (LAT)
Laboratory Animal Technologists (LATG) |
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Definition
| Daily care, ensure all environmental variables are controlled, may also function as research technicians |
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Term
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Definition
| Usually has training in laboratory animal care specifically, member of ASLAP and/or ACLAM, oversees all las animal models |
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Term
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Definition
| Responsible for operations of facility, including staff supervision and record maintenance |
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Term
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Definition
American Association of Laboratory Animal Science
Formed in 1950, develops requirements for LATs, LAGTs, and ALATs |
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Definition
American Society of Laboratory Animal Practitioners
Group of veterinarians w/special interest in lab animals |
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Definition
American College of Laboratory Animal Medicine
Provides standards of training for vets in this field, also performs the cert exam necessary for vets |
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Definition
Animal Welfare Act
1966, revised since, governs the sale, transport, and use of animals (excludes farm animals), required the formation of IACUC |
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Definition
Institutional Animal Care and Use Committee
All animals in research in US must be approved by IACUC, independent entity that cannot be overruled, made up of a group w/i the research facility |
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Definition
United States Department of Agriculture
Enforces AWA, has APHIS and REAC as its main agencies |
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Definition
Animal and Plant Health Inspection Service
Inspects research facilities for AWA violations yearly |
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Definition
Regulatory Enforcement and Animal Care
Enforces penalties for violations of AWA |
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Definition
The Guide for the Care and Use of Laboratory Animals
Primary reference for animal care and use in research, species not included in the AWA are given regulations and recommendations in the guide |
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Definition
Public Health Policy on Humane Care and Use of Laboratory Animals
An agency w/i US Department of Health and Human Services, addresses the use do euthanasia to relieve pain and suffering in lab animals |
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Term
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Definition
cause: pasteurella multocida, bordatella bronchiseptic
symptoms: sneezing, mucopurulent nasal discharge, conjuctivitis
transmission: direct contact, aerosolization
treatment: supportive, long-term antibiotics |
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Term
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Definition
ulcerative pododermatitis
moist dermatitis
necrobacillosis (schmorl's disease)
fly strike |
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Term
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Definition
cause: eimeria
symptoms: diarrhea
transmission: poor husbandry and stress
treatment: sulfa-drugs, ivermectin, toltrazuril |
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Term
| rotavirus & coronavirus (rabbit) |
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Definition
cause: they are the cause
symptoms: diarrhea
transmission: direct contact
treatment: supportive care |
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Term
| enterotosemia & enteropathy (rabbits) |
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Definition
cause: e. coli, lawsonia, clostridium
symptoms: anorexia, diarrhea, wasting
transmission: poor husbandry, stress
treatment: supportive care, antibiotics, dietary fiber |
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Term
| venereal spirochetisis (rabbits) |
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Definition
cause: treponema paraluis cuniculi
symptoms: erythema, edema of genetalia, lesions
transmission: genital-genital or facial-genital, fomites
treatment: penicillin |
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Term
| cerebral larval migrans and fatal CNS disease |
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Definition
cause: baylisascaris
symptoms: torticollis (head tilt, barrel roll), ataxia, tremors, falling
transmission: food contamination
treatment: there is no treatment |
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Term
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Definition
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Term
| rabbit hemorrhagic disease (RHD) |
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Definition
cause: calicivirus
symptoms: few, too rapid
transmission: poor husbandry
treatment: no treatment |
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Term
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Definition
cause: obeliscoides ciniculi
symptoms: GI signs
transmission: contaminated food
treatment: supportive care |
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Term
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Definition
cause: staph
symptoms: septicemia, abscess, mastitis, comjunctivitis
transmission: poor husbandry and stress
treatment: supportive care, antibiotics |
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