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VET121_Barbiturates
Malcolm quiz 3
22
Veterinary Medicine
Not Applicable
02/26/2013

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Cards

Term
What are barbiturates derived from?
Definition
Barbituric acid
Term
How do barbiturates act?
Definition
By progressive depression of the central nervous system
Term
How do barbiturates work? What do they get absorbed in?
Definition
They get absorbed into the brain, which produces unconsciousness
Term
When does recovery occur?
Definition
When the brain levels fall too low to affect the brain
Term
Where is it metabolized? Excreted?
Definition
Metabolized by liver and excreted by kidney
Term
What are the reversal agents for barbiturates?
Definition
None
Term
Are barbiturates known for their analgesic properties? Are they controlled?
Definition
No, and yes...the human race has made it possible to get addicted-genius!
Term
How do we administer barbiturates?
Definition
Powder form that needs to be reconstituted. IV, give to effect.
Term
who do we need to monitor closely during the use of barbiturates?
Definition
Patients with respiratory depression and apnea
Term
Barbiturates depress what?
Definition
Cardiovascular system and respiratory system
Term
Why should hypoproteinemic patients receive a lower dose of a barbiturate?
Definition
Because they're normally partially protein-bound...so if the animal don't got lots of proteins, den dey could be kilt frum ovadoze
Term
It has various interactions with other drugs, what do we do?
Definition
Look em up as needed
Term
To avoid or correct going too deep, what can we do?
Definition
Bag regularly, or use lower dose. (oh, or just avoid it all together)
Term
Is it safe for sighthounds, or lean patients?
Definition
Yes, it's safe, it just causes them to sleep for days
Term
Why do the skinny minnies of dog world sleep forever and a day when given barbiturates?
Definition
Because they don't have much fat for the barbiturate molecules to redistribute to-so it'll stay in their blood and brain...deepening and prolonging anesthesia
Term
If injected perivascularly, what happens?
Definition
Can cause tissue damage
Term
Why is it bad if you accidentally give it perivascular, or under-dose a patient with barbiturates?
Definition
The patient gets put into excitement stage, and at that point it's hard to get them deeper. It will be harder to anesthetize, and it'll most likely take more drugs
Term
Prolonged recovery can be caused by what?
Definition
#liverprobz #kidneyprobz #hypothermia (because the liver enzymes are not as active)
Term
Soooo...who should we basically avoid when giving barbiturates?
Definition
The sickies
Term
What are the most commonly used barbiturates in vet med?
Definition
Thiopental - Pentothal (CIII)
Term
Not so commonly used barbiturates?
Definition
Generic Trade
Pentobarbital - Nembutal
Thiamylal - Biotal, Surital
Methohexital - Brevital
Term
Which one is not commonly used but is the only one still available?
Definition
Generic Trade
Pentobarbital-Nembutal
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