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Vascular 2
Vascular 2
19
Veterinary Medicine
Not Applicable
02/06/2017

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Cards

Term
How do electrolytes, glucose and amino acids move across capillaries?
Definition
diffusion through capillary pores
Term
How does O2, CO2, fatty acids & hormones move across capillaries?
Definition
diffusion through endothelial cells of capillaries
Term
Why does the liver have very wide capillary pores/clefs?
Definition
the liver produces plasma proteins, which need to be able to pass through these pores
Term
Why is it important for the brain to have very small capillary clefts?
Definition
to maintain the blood brain barrier
Term
What is Fick's Law?
Definition
Rate of diffusion = (Diffusion Coefficient X Concentration Gradient) / Distance
Term
How does lipid solubility affect diffusion coefficient? Molecular size?
Definition
More soluble = greater diffusion coefficient
Smaller size = greater diffusion coefficient
Term
Net osmotic pressure favors water movement (into/out of) capillaries
Definition
into (favours water reabsorption)
Term
Net hydrostatic pressure favours water movement (into/out of) capillaries
Definition
out of (into interstitial fluid)
Term
What would effect would an increase in hydrostatic pressure have on the tendency for water to filter from capillaries into the interstitium?
Definition
would promote filtration
Term
What would effect would an increase in oncotic pressure difference have on the tendency for water to filter from capillaries into the interstitium?
Definition
decrease filtration
Term
What would effect would an increase in water permeabilty of capillary endothelium have on the tendency for water to filter from capillaries into the interstitium?
Definition
would promote filtration
Term
How does excess interstitial fluid get returned to the CV sytem?
Definition
via lymphatics (subclavian veins feeding into the vena cava)
Term
What is lymph?
Definition
water + protein collected from interstitium
Term
How does lymph move throughout the lymphatic system?
Definition
Bulk Flow
-skeletal muscle contraction, lung expansion/contraction, one way valves & smooth muscle in vessels all move lymph around
Term
What causes edema?
Definition
-excess filtration of fluid from capillaries into interstitium

-loss of function of the lymphatic system
Term
What is the correlation between venous pressure & edema?
Definition
Increased venous pressure will increase capillary hydrostatic pressure, causing a buildup of fluid in the interstitium
Term
Why might kidney failure or loss of GI absorption capacity lead to edema?
Definition
protein-losing diseases like these can ead to hypoproteinemia, which leads to a loss of oncotic pressure. Fluid will be more inclined to move from capillaries into interstitium, leading to edema.
Term
Why might liver failure lead to edema?
Definition
loss of ability to produce proteins = lower oncotic pressure = fluid moves to interstitium
Term
Pulmonary edema is often due to....
Definition
increased venous pressure leading to an increase in hydrostatic pressure
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