Term
| What allele is associated with UDS in dogs? |
|
Definition
| Canine leukocyte antigen DQA1-00201 |
|
|
Term
| What percentage of Akitas may be affected with UDS? |
|
Definition
4.1 %
There are sporadic reports in other breeds |
|
|
Term
| What are the common derm clinical signs of UDS? |
|
Definition
Leukotrichia with erythema
Leukoderma
Ulceration
Crusting (nasal planum and eyelids)
mucocutaneous erosions
alopecia (periocular) |
|
|
Term
| What is the typical age on onset for UDS? |
|
Definition
|
|
Term
| What are the common ocular clinical signs of UDS? |
|
Definition
Bilateral panuveitis with pigment dispersion in the anterior chamber
Retinal detachment
Glaucoma
Preiridal fibrovascular membranes
Posterior synechiae
Cataract
Optic nerve cupping
Retinal atrophy |
|
|
Term
| What two diseases may result from lesions due to T lymphocyte-mediated damage to melanocytes? |
|
Definition
- Uveodermatological syndrome
- Vitiligo
|
|
|
Term
| What dog breeds are predisposed to Uveodermatologic syndrome? |
|
Definition
- Akita
- Siberian husky
- Samoyed
|
|
|
