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Urolithiasis
Vet115
30
Veterinary Medicine
Undergraduate 1
03/04/2010

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Term
What is cystitis? What are some clinical signs that would be seen?
Definition
inflammation of the bladder; signs are pollakiuria, dysuria, stranguria, and hematuria (with or w/o infection)
*client picks up on the signs
Term
What are uroliths? where are most seen, male or female? if they are in the urethra, what happens?
Definition
calculi or stones (made of minerals that come together) in the kidney, ureter, bladder (most common) and urethra; most seen in the female bladder (they are bigger so stuck in bladder, not too big problem bc can walk around for while with them)
*if in the urethra, then see obstruction and more common in males bc smaller stones so get stuck especially in male bc long and narrows in places
Term
An obstruction in the urethra or other place is a...
Definition
Emergency!
Term
What does the term urolith mean? What is normal amount seen in small animal? How are they formed? What common factors lead to it being formed?
Definition
"urine rocks"; less than 1% is seen normally; they are formed by the nucleus forming first (s.th serves as it, many things can) and then get crystal precipitation around it in concentrated urine
*pH dependent formation and diet related
Term
Once formed, uroliths can do what?
Definition
pass out of the urinary tract, dissolve on own, remain in bladder, obstruct the urethra (in males more often again at the os penis or ischiatic arch)
Term
Why do stones obstruct males so often?
Definition
the urethra narrows coming out of the bladder, gets narrow at os penis and turns on self at ischiatic arch so narrows again; many places get stuck
Term
A blocked dog looks how and is most likely from what cause? A blocked cat?
Definition
painful, licking, cause = stones; in cat --> bc of grit and not stones, will be straining, crying, no urine
Term
What occurs in the process of urethral obstruction?
Definition
pressure backs up to the kidneys after becoming blocked; rapid onset azotemia (animal gets depressed), hyperkalemia common (where K+ increasing bc kidney not relieving and passing waste out); death follows unless obstruction relieved for dog and cat (bc K+ stops the heart)
*step 1- relieve obstruction by pushing stone back in or urethrotomy (cut over urethra...not fun for them)
*step 2- after sx, radiograph or ultrasound to make sure got all stones out or have unhappy clients!
Term
What is the role of crystals to the technician?
Definition
more common than stones...usually present with stones if seen; clinical sig overrated bc most dogs have them but no stones
Term
Name some types of stones
*are all major in eyes of vet med?
Definition
struvite (phosphate) which looks like grit sometimes; oxalate, urate, cystine, silica
*have to know which type in order to prevent or comes back (HIGH recurrence rate)
*usually have one major and couple minor ones
Term
Name some features about struvite uroliths
Definition
struvite most common type urolith (50-55%); called Mg Ammonium Phosphate aka triple phosphate or phosphate (may or may not be triple present); appear in alkaline urine; bacterial infection very common with this ("infection stones" bc ass'd with infection so much); most common in bladder of female
Term
How are struvites diagnosed?
Definition
by radiography bc theyre radiodense (so will show up) and contrast study not usually needed; urinalysis (coffin lid crystals, ph >7)
Term
what kind of stones do dogs get?
Definition
struvite; calcium oxalate; urate; silica; cystine
Term
What is a pneumocystogram?
Definition
where insert catheter in bladder, pump in air and xray; air = negative constrast (a positive contrast not work for stones, not see them well)
Term
How do you treat struvite stones?
Definition
control infection; acidify urine; calculolytic diet (s/d) or the stone diet which contains high salt, low phosphorus, low mg, and low protein; or surgery
*with the diet, takes longer and over time stones dissolve, 3mo or 6mo etc, usually for females and males must remove the stones...can't try to wait, only surgery if obstructed
Term
Can you just guess at what stones are by looking at them?
Definition
No, must send out to see what it is; analyze! Should do before pay all money for surgery or food but clients don't want to sometimes
Term
Are contrast studies always needed for stones?
Definition
no
Term
What is a staghorn calculus?
Definition
in the kidney; usually must euthanize animal because dying...no way remove both kidneys with stones in them
Term
Name features of calcium oxalate crystals in dogs
Definition
26-35% of canine uroliths; most common in fru fru dogs like min schnauzer and lhasa apso and yorkshire terrier; form in acid urine; signs are same...PU/PD, hematuria, and pollakiuria
Term
How do you dx calcium oxalate stones?
Definition
radiography bc radiodense; urinalysis, look like square with x although crystals not always apparent in urine
Term
how do you tx calcium oxalate crystals in dogs?
Definition
cystotomy often needed; diet won't dissolve them! (need make choice then bc dog has stones so what to do...)
*diets exist to help PREVENT stones but not dissolve and tx- Hills Xd (are clients willing pay money on that?)
Term
Describe features of urate uroliths
Definition
dalmations get these more bc cant metabolize uric acid well, bulldog too recently bc same genetic defect; excrete lg quantities in urine; no stones w/o crystals here! most small and spherical (commonly block male urethra); have 1 or many present; radiolucent (xray pass thru but shows up on ultrasound), need sx (cystotomy); small ones are male problem and lg are female bc males have smaller urethra
Term
How do you prevent urate stones?
Definition
diet with low protein, alkaline producing diet (conc urine helps stone production-bad) with no extra salt U/D; allopurinol which inhibits production of uric acid; control urinary tract infection; increase urine volume
Term
Name features of cystine stones
Definition
not very common; inherited metabolic defect; cystine not reabsorbed like should be and cystinuria is present! stones are radiolucent, form in acid pH, most in male's urethra (bc small stones); should've seen in urine as crystals first!
Term
Name features of silica stone? Do you see as much?
Definition
Not common, rare; silica is ingredient in glass...since not eating glass must be coming from a source; look at water source...from water supply usually with silica in it
Term
How do you analyze stones?
Definition
cant tell by looking, many of mixed nature and need quantitative analysis by sending out to ID everything; need to know to tx and prevent recurrence; HIGH RECURRENCE rate if no change diet etc
Term
Is it only small animals getting stones?
Definition
no, goats can get...or plugged bc of stone in urethral process "water belly"
Term
Is it always a stone that blocks a dog?
Definition
no, TCTS (trans. cell tumors) can make look like stone and not be able pass catheter sometimes; look under microscope and are the trans cells normal looking?
Term
Is feline urolithiasis uncommon or common?
Definition
More common...ppl see faster than with dogs too!
Term
What does FLUTD stand for? how many cats does it affect? what signs do you see with it? how does it originate?
Definition
feline lower urinary tract disease (basically all disorders involving urinary probs); 1% of pop; see dysuria, pollakiuria, hematuria, and crystalluria with it; origin is diet, water consumption (HUGE bc cats dont drink enough and cats can concentrate urine better, increases opportunity to make crystals) and stress
*pathology different from dogs
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