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Details

Treatment for bacterial Skin Infections
N/A
16
Veterinary Medicine
Graduate
03/24/2015

Additional Veterinary Medicine Flashcards

 


 

Cards

Term
Clinical signs of bacterial skin infections
Definition

should be compatibile with pyoderma

- recognise the depth of pyoderma- surface, superficial,deep- each implies a diff therapy and prognosis

- if see seborrhoeic pyoderma- bacterial overgrowth syndrome

- papules, pustules and scaling - superficial folliculitis

- erosions and ulcers- pyotraumatic dermatitis

- ulcers and draining tracts- deep pyoderma

 

 

 

Term
Site selection for cytology and culture
Definition

Primary lesion: leading edge of ulcers, non ulcerated nodules, intact pustules, furuncles

 

avoid: secondary, chronic and excoriated lesions- unless they are the only lesions

 

Gently CLIP HAIR

GENTLY debride crust or haemorrhage

 

Impression smear or direction impression smear

Adhesive tape strips

FNA

Staining 

Term
[image]
Definition
Staphylocci pyoderma
Term
[image]
Definition
Gram negative pyoderma
Term
[image]
Definition
Bacterial overgrowth syndrome
Term
When can you do Emperical choice of antibiotics for pyoderma
Definition

Must: 

- non life threatening infection

- first episode

- SURFACE OR SUPERFICIAL PYODERMA

- consistent with STAPHYLOCOCCI

 

Term
When to do Bacterial culture and sensitivity for pyoderma
Definition

FOR: 

life threatening

deep pyoderma

clinical signs and cytology not consistent

Rod bacteria on cytology

Empirical ab not effective

- kirby bauer dis diffusion tests use antibiotic paper discs- zone of inhibition around the disc determines whether the bacteria are susceptible or resistant. 

- MIC- using E strips

- further testing PCR to confirm MRS( meticillin resistant staph)

 

Term
When to suspect antibiotic resistance
Definition

after one or more BS ab course

non healing wounds

post op infections

 

if using topical- use culture results as guide for treatment 

Term
Does the infection require treatment?
Definition

not all require systemic AB

mild, non LT, limited focal infections

consider topical ABs or antimicrobials 

 

 

Term
First line AB for pyoderma
Definition
[image]
Term
Second line ab for pyoderma
Definition

broad spectrum drugs important for animals and humans

- only if culture evidence shows that the first line defense ab wont work- need to prevent resistance. 

 

Enrofloxacin, marbofloxacin...FQs

Term
Third line ab for pyoderma
Definition

treating multi drug resistant organisms

most are not licensed for animals

 

Aminoglycosides, chloramphenicol, rifampin

Term
Penetration into inflammed tissues
Definition

skin and chronic inflammation relatively avascular

- pus and decrotic debris inactivate sulfonamides, macrolides, lincosamides and aminoglycosides. 

- FQs- penetrate well into inflamed skin

- FQs, lincosamides, macrolides- accumulate in phagocytes

Term
Treat to clinical cure
Definition

resolution of lesions and normal cytology

surface and superficial- usually 2-3 weeks

deep- often improved in 2 weeks, full res. in 4-6 weeks

REGULAR check ups to check response- every 7-14 days! 

Term
Recurrent pyoderma
Definition

- look for underlying cause, primary is rare

- topical antimicrobial shampoos and rinses

- maybe immunostimulants? ( staph vaccines, staph phage lysate)

- pulse ABs are a last resort- idiopathic recurrent, atopic dermatitis, cefalexin or clavulanate-amoxicillin

 

Term
Topical antibacterial therapy
Definition

warm water baths or soaks

whirlpool baths

showers

contact time 10 min

2-3 times a week initially

2-4 times monthly for maintenance 

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