| Term 
 
        | Functions of the Integumentary System |  | Definition 
 
        | PROTECTION Body temperature regulation
 Cutaneous sensations
 Metabolic functions
 Blood reservoir
 Excretion
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        | Term 
 | Definition 
 
        | Low pH secretions retard bacterial activity |  | 
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        | Term 
 
        | Protection/Physical/mechanical barriers: |  | Definition 
 
        | Keratin and glycolipids block most water and water- soluble substances Limited penetration of skin by lipid-soluble substances, plant oleoresins (e.g., poison ivy), organic solvents, salts of heavy metals, some drugs
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        | Term 
 
        | Protection/Biological barriers |  | Definition 
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        | Term 
 
        | Function/Body temperature regulation |  | Definition 
 
        | ~500 ml/day of routine perspiration (at normal body temperature) At elevated temperature, dilation of dermal vessels and increased sweat gland activity cool the body
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        | Term 
 
        | Function/Cutaneous sensations |  | Definition 
 
        | Temperature, touch, and pain |  | 
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        | Term 
 | Definition 
 
        | Synthesis of vitamin D precursor and collagenase |  | 
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        | Term 
 
        | Function/Blood reservoir— |  | Definition 
 
        | up to 5% of body’s blood volume |  | 
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        | Term 
 | Definition 
 
        | nitrogenous wastes and salt in sweat |  | 
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        | Term 
 
        | Integument Consists of three major regions: |  | Definition 
 
        | Epidermis—superficial region Dermis—middle region
 Hypodermis (superficial fascia)—deepest region
 Subcutaneous layer deep to skin (not technically part of skin)
 Mostly adipose tissue
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        | Term 
 | Definition 
 
        | Keratinized stratified squamous epithelium Cells of epidermis
 Keratinocytes—produce fibrous protein keratin
 Melanocytes
 10–25% of cells in lower epidermis
 Produce pigment melanin
 Tactile (Merkel) cells—touch receptors
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        | Term 
 | Definition 
 
        | Most superficial layer s of dead cells represented only by flat membranous
 sacs filled with keratin
 Protects from abrasion and penetration
 Waterproofs
 Barrier against biological, chemical, physical assaults
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        | Term 
 | Definition 
 
        | Three to five layers of flattened cells, organelles deteriorating; cytoplasm full of
 granules
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        | Term 
 | Definition 
 
        | Several layers of keratinocytes Cells contain thick bundles of
 intermediate filaments made of pre-keratin
 prickly.
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        | Term 
 | Definition 
 
        | Deepest epidermal layer; one row of actively mitotic stem cells; Active stem cells – 25-45
 days to the skin surface
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        | Term 
 | Definition 
 
        | Strong, flexible connective tissue 2 layers: papillary, reticular
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        | Term 
 | Definition 
 
        | Areolar connective tissue with collagen and elastic fibers and blood vessels Dermal papillae contain:
 Capillary loops
 Meissner’s corpuscles
 Free nerve endings
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        | Term 
 | Definition 
 
        | ~80% of the thickness of dermis Collagen fibers provide strength and resiliency
 Elastic fibers provide stretch-recoil properties
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        | Term 
 
        | Three pigments contribute to skin color: |  | Definition 
 
        | melanin Carotene
 Hemoglobin
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        | Term 
 | Definition 
 
        | Sweat glands Oil glands
 Hairs and hair follicles
 Nails
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        | Term 
 | Definition 
 
        | Two main types of sweat (sudoriferous) glands Eccrine
 Apocrine
 Eccrine  sweat glands—abundant on palms, soles, and forehead
 Sweat: 99% water, NaCl, vitamin C, antibodies, dermcidin, metabolic wastes
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        | Term 
 
        | appendages/sweat glands types 2 |  | Definition 
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        | Term 
 | Definition 
 
        | Widely distributed Most develop from hair follicles
 Become active at puberty
 Sebum
 Oily  secretion
 Bactericidal
 Softens hair and skin
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        | Term 
 
        | appendages/hair/structure |  | Definition 
 
        | Consists of dead keratinized cells Contains hard keratin; more durable than soft keratin of skin
 Hair pigments: melanins (yellow, rust brown, black)
 Gray/white hair: decreased melanin production, increased air bubbles in shaft
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        | Term 
 
        | appendages/NAILS/structure |  | Definition 
 
        | modification of the epidermis on the distal, dorsal surface of fingers and toes |  | 
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        | Term 
 
        | Define the term histology. |  | Definition 
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        | Term 
 
        | List and compare the four major tissue types. |  | Definition 
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        | Term 
 
        | function and structure of different types of membranes |  | Definition 
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        | Term 
 | Definition 
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