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Test 2 Summary of Skeletal muscle table 10.2
Skeletal Muscle Fiber Proteins
13
Anatomy
Undergraduate 1
10/20/2009

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Term
What is a contractile protein?
Definition
Proteins that generate force during muscle contractions
Term
what is Myosin?
Definition
A contractile protein-- makes up thick filament--
Term
what does myosin consist of ??
Definition
tail, 2 myosin heads--bind at myosin binding sites on actin molecules of thin filament during contraction
Term
What is actin?
Definition
A contractile protein--main component of thin filament--ea actin mol is a myosin-binding site where a myosin head of thick fil binds during a contraction
Term
regulatory proteins?
Definition
proteins that help to switch the muscle contraction on and off
Term
what is tropomyosin?
Definition
a regulatory protein-- a component of thin filament--tropomyosin covers the myosin-binding site on actin molecules when a skeletal muscle is relaxed--preventing myosin from binding to actin
Term
what is troponin?
Definition
regulatory protein--that is a compon. of thin fila-- Ca ions bind to troponin it undergoes a change in shape.... muscle contraction subsequently begins as myosing binds to actin
Term
structural proteins
Definition
proteins that keep the thick/thin filaments of the myobibrils in proper alignment--give myofibrils elasticity and exxtensibility--links the myofibrils to the sarcolemma and extracellular matrix
Term
titin
Definition
structural protein connects a z eis to the m line of the sarcomere, helping to stabilize the position of the theick filament. -- accounts for much of the elasticityand extensibility of myofibrils
Term
a-actinin
Definition
structural protein of the A discs that attahes to the actin mol of thin filaments and to the titin molecules
Term
myomesin
Definition
structural protein that forms the M line of th asarcomere, binds to the titin mol and connects adjacent thick filaments to one another
Term
nebulin
Definition
structural protein that wraps around the entire length of each thin filament; it helps anchor the thin fil to the Z disc and regulates the length of the thin fila during development
Term
dystrophin
Definition
structural protein that links the thin filaments of the sarcomere to integral membrane proteins in the sarcolemma, which are attached in turn to proteins in the connective tissue matrix that surrounds muscle fibers.
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