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Signaling Molecules
n/a
31
Anatomy
Graduate
08/21/2010

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Cards

Term
FGF
Definition
secreted by mesenchyme in lungs to induce branching of lung bud
Term
FGF
Definition
Promotes formation of ventral structures
Term
FGF
Definition
Required for neural crest cell formation
Term
FGF 8
Definition
Down regulates E-cadherin which holds epiblast together so it can form germ layers.
Term
FGF 8
Definition
regulates Brachyury T which promotes mesoderm cell specification
Term
FGF8
Definition
Induces expression of Nodal on Left side and maintains progressive zone in limb development
Term
WNT
Definition
causes mesenchyme of kidney to be turned into epithelium for nephron formation.
Term
WNT
Definition
secreted by epidermis in neural crest cell formation but not present for early heart development
Term
Organizer
Definition
antagonizes BMP's to form dorsal structures
Term
SNAIL
Definition
transcription factor for right sidedness
Term
SRY
Definition
encodes testes determining factor which causes the production of testosterone
Term
FOX-D3
Definition
marker for neural crest cells
Term
SOX9
Definition
Inhibitor of WNT4 in male and female genital production
Term
DAX 1
Definition
inhibits testes formation
Term
Angiopoietin
Definition
forms blood islands to form smooth muscle
Term
WT 1
Definition
makes tissue competent to respond to uteric bud. Regulates GDNF and HGF which cause growth of bud
Term
ZP3
Definition
binds sperm to egg
Term
PITX 2
Definition
establishes left sidedness
Term
FGF10
Definition
induces apical ectodermal ridge in limb development
Term
FGF 2
Definition
required for generation of blood islands
Term
BMP 2
Definition
blocks foregut endoderm from forming liver tissue
Term
BMP 4
Definition
promotes formation of ventral structures
Term
BMP's
Definition
Block foregut endoderm from forming liver tissue. Secreted by neuroectoderm in neural crest cells
Term
BMP's
Definition
Contribute to somite formation
Term
BMP's
Definition
present for early heart development
Term
VEGF
Definition
required for blood islands to create tubes. Causes loosening of cell to cell contacts for angiogenesis to occur
Term
NKX 2.5
Definition
transcriptional factor for heart formation
Term
HNF 3 and 4
Definition
specific genes that express liver formation
Term
Sonic Hedgehog
Definition
Induction of mesenchymal/endoderm reaction. Secreted to turn off tips of growing tissue in lung bud so branching occurs
Term
SHH
Definition
acts as repressor for left sided genes
Term
SHH
Definition
contributes to somite formation
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