Term
| Genus and species of the mouse |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
DBA
BALB/C
New Zealand white or black
C57BL
C3H |
|
|
Term
| What is the oldest inbred mouse strain? |
|
Definition
|
|
Term
| What is unique about C57BL mice? |
|
Definition
| Prone to idiopathic ulcerative dermatitis |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Normal mouse respiratory rate |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Genus and species of the rat |
|
Definition
|
|
Term
|
Definition
Wistar
Spraugue-Dawley
Long Evans |
|
|
Term
| Appearance of Long Evans stock |
|
Definition
|
|
Term
|
Definition
Fischer344 (F344)
Lewis
Spontaneously hypertensive (SHR)
Wistar-Kyoto (WKY)
Buffalo (BUF) |
|
|
Term
| Full name of "WKY" rat strain |
|
Definition
|
|
Term
| Full name of "SHR" rat strain |
|
Definition
| Spontaneously hypertensive |
|
|
Term
| Use of F344 rat strain in research |
|
Definition
| Testicular tumors, leukemia, and retinal degeneration |
|
|
Term
| Use of Wistar-Kyoto rat strain in research |
|
Definition
|
|
Term
| Use of Buffalo rat strain in research |
|
Definition
| Hashimoto's Disease (immune mediated thyroid dz) |
|
|
Term
| Genetically-modified rat strains |
|
Definition
Zucker Diabetic Fatty
Athymic nude rat
P53 knockout
RIP-HAT
Frantic |
|
|
Term
| Size of Zucker Diabetic Fatty rat |
|
Definition
|
|
Term
| Use of P53 knockout rat in research |
|
Definition
|
|
Term
| Use of RIP-HAT rat in research |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Normal rat respiration rate |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| When does cannibalism occur in rats? |
|
Definition
|
|
Term
|
Definition
| Place on neonate's abdomen where you can see if the belly is full of milk or not |
|
|
Term
| At what age do rats and mice reach sexual maturity? |
|
Definition
|
|
Term
| When does post-partum estrus occur? |
|
Definition
| 24 hours after parturition |
|
|
Term
|
Definition
| All four feet on the floor, eyes and ears alert |
|
|
Term
| Signs of stress or pain in rodents |
|
Definition
Decreased food/water intake (= decreased output)
Dehydration (sunken eyes)
Aggression
Self mutilation
Scruffy coat |
|
|
Term
| What is chromodacryorrhea? |
|
Definition
| Harderian glands behind the eyes of rats and mice produce red tears |
|
|
Term
| Modes of transmission of hantavirus |
|
Definition
| Bites, aerosols, direct contact, ingestion of contaminated food/water |
|
|
Term
| Which diseases does hantavirus cause? |
|
Definition
Hemorrhagic fever with renal syndrome
Hantavirus pulmonary syndrome |
|
|
Term
|
Definition
|
|
Term
| What are the clinical signs of SDA? |
|
Definition
Keratoconjunctivitis
Cervical/jaw swelling |
|
|
Term
|
Definition
| Usually resolves on its own, but can treat KCS until then |
|
|
Term
|
Definition
|
|
Term
| How is Sendai virus transmitted? |
|
Definition
|
|
Term
|
Definition
| Infectious diarrhea of infant rats |
|
|
Term
| What kind of disease is IDIR? |
|
Definition
|
|
Term
| What are the clinical signs of IDIR? |
|
Definition
| Soft, yellow feces or dried feces around anus of rat pups |
|
|
Term
|
Definition
| Murine respiratory mycoplasmosis |
|
|
Term
|
Definition
|
|
Term
|
Definition
| Snuffling, nasal/ocular discharge, head tilt/circling |
|
|
Term
| Cause of Tyzzer's disease |
|
Definition
|
|
Term
| Clinical sign of Tyzzer's |
|
Definition
| Diarrhea, dehydration, anorexia |
|
|
Term
| In which strain of rat do up to 50% get mammary tumors? |
|
Definition
|
|
Term
| Where is the Zymbal's gland? |
|
Definition
|
|
Term
| What is significant about Zymbal's gland tumors? |
|
Definition
| Locally invasive but not metastatic |
|
|
Term
|
Definition
| Chronic progressive Glomerulonephropathy |
|
|
Term
|
Definition
| Kidney disease in elderly rats |
|
|
Term
| Causes of ringtail in rats |
|
Definition
| High temperature and low humidity |
|
|
Term
|
Definition
| Necrotic constrictions on the tail |
|
|
Term
|
Definition
| Lymphocytic choriomeningitis |
|
|
Term
|
Definition
| Aerosol, bite wounds, arthropod vectors |
|
|
Term
| Clinical signs of Sendai virus in mice |
|
Definition
| Weight loss, rough hair coat, dyspnea, teeth chattering, conjunctivitis |
|
|
Term
| Mouse diseases caused by Helicobacter |
|
Definition
|
|
Term
| Types of mouse parvovirus |
|
Definition
Mouse parvovirus (MPV)
Mouse minute virus (MMV) |
|
|
Term
|
Definition
|
|
Term
| What is significant about mouse hepatitis virus? |
|
Definition
Highly contagious coronavirus
One of the most common in resarch
Screened for |
|
|
Term
|
Definition
| Epizootic diarrhea of infant mice |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
Encephalitis
Pneumonia
Hepatitis |
|
|
Term
| What is the most common nematode in mice? |
|
Definition
|
|
Term
| Common genus of mouse pinworms |
|
Definition
|
|
Term
| What is the Whitten effect? |
|
Definition
| Females synchronize estrous |
|
|
Term
| What is the Bruce effect? |
|
Definition
| Spontaneous abortion of early pregnancies when introduced to a new male |
|
|
Term
| What is the Lee Boot effect? |
|
Definition
| Induction of anestrous when no males are present |
|
|
Term
| Restraint methods of rodents |
|
Definition
Scruff
Hot dog hold
Decap-a-cone |
|
|
Term
| What percent of a mouse's weight is blood? |
|
Definition
|
|
Term
| What percent of a mouse's total blood volume can be collected in a recovery procedure? |
|
Definition
|
|
Term
| Survivable blood collection methods from mice |
|
Definition
Tail nick
Tail snip
Tail vein
Retro-orbital sinus
Saphenous |
|
|
Term
| Non-survivable blood collection methods from mice |
|
Definition
|
|
Term
| How much tail can be removed during a tail snip? |
|
Definition
|
|
Term
| How to perform a tail nick in a mouse |
|
Definition
Warm the mouse under a lamp
Restrain (tube or anesthesia)
Use #11 blade to nick tail vein
Let blood flow into a tube, do not squeeze/milk tail |
|
|
Term
| How to perform mouse IV injection |
|
Definition
Warm mouse under heat lamp
Restrain in tube/anesthesia
Insert needle halfway down tail, parallel to the vein
DO NOT ASPIRATE!
Inject very slowly - vein will blanch |
|
|
Term
| Maximum intradermal dosage |
|
Definition
|
|
Term
| How often can blood be collected from a mouse? |
|
Definition
| No more than once every three weeks |
|
|
Term
| How to perform an IC blood draw |
|
Definition
Put under DEEP anesthesia
Insert needle under sternum, pointing cranial and slightly left
Collect up to 1 mL of blood |
|
|
Term
|
Definition
| Torb, ketofen, topical analgesics put in surgical wound |
|
|
Term
| Issues with using Avertin |
|
Definition
Must be compounded in-lab
Must be filtered and extremely aseptic |
|
|
Term
| Isoflurane levels for rodent gas anesthesia |
|
Definition
3-4% for induction
1.25-1.75% for maintenance |
|
|
