Term
|
Definition
AV 1-5
based on N-protein (nucleocapsid protein) |
|
|
Term
|
Definition
8 ecotypes
based on geographical area
intraspecies transmission predominates |
|
|
Term
| Rabdoviridae Characteristics |
|
Definition
enveloped RNA virus, bullet shaped, medium sized
negative sense |
|
|
Term
|
Definition
neurons
secretory epithelium |
|
|
Term
| Vesicular Stomatitis Virus Tropism |
|
Definition
|
|
Term
| Rabdoviridae Transmission |
|
Definition
|
|
Term
| Vesicular Stomatitis Virus Characteristcs |
|
Definition
REPORTABLE
zoonotic
short incubation period |
|
|
Term
| Vesicular Stomatitis Virus Signs |
|
Definition
Horses - tongue lesions and lameness
Pigs - snout and coronary band lesions and lameness
Cattle - vesicles on dental pad, otngue, thickened coronary band |
|
|
Term
| Vesicular Stomatitis Virus Transmission |
|
Definition
| vesicular fluids, saliva, abrasions, arthropod vectors |
|
|
Term
| Rabies Virus Characteristics |
|
Definition
lyssavirus, REPORTABLE, zoonotic
forms envelope from ER |
|
|
Term
| Rabies Virus Pathogenesis |
|
Definition
skin,muscle wounds from bite
primary viral replication at site of entry
invades nerve endings via ACh receptors
Then begins to spread to CNS
Reaches ganglia and neurons in CNS to cause dysfunction
Goes out via peripheral nerves to salivary glands and sheds virus via saliva |
|
|
Term
| Rabies Virus Incubation Period |
|
Definition
3-12 weeks
reported to be up to 6 months in racoons
reported to be up to 7 years in people
depends on how far the wound is from brain |
|
|
Term
|
Definition
furious form - limbic system involvement, encephalitis, behavioral changes, hydrophobia
paralytic/dumb form - neocortex involvement, depression, incoordination
seizures-->paralysis-->coma-->death |
|
|
