Term
| What do we evaluate RBCs for? |
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Definition
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Term
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Definition
normocytic- normal
macrocytic- larger than normal
microcytic- smaller than normal
anisocytosis- variation of sizes |
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Term
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Definition
normochromic- normal color
hypochromasia- lack of color
polychromasia- many colors/variation of colors |
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Term
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Definition
| spiculated cells, irregular shaped projections. Seen with liver, and spleen issues. Also seen with Hemangiosarcoma. |
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Term
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Definition
| have even regular shaped projections, seen in Rattlesnake bites, or lymphosarcoma, |
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Term
Leptocytes/Codocytes
(could be Bar or Target) |
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Definition
dark dot or dark line in middle
We class these as Target or Bar cells. Seen in liver disease, iron deficiency, regen anemias, but remember Target cells are often seen in normal animals. |
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Term
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Definition
| mouth cells, folding cell, clear line in middle. These cells are losing the ability to carry oxygen so they are folding. Often seen with hypochromic cells. |
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Term
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Definition
| tear drop shaped, can be seen in patients with myelofibrosis, sometimes human error |
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Term
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Definition
| dense, small dark round, lacking central pallor- “Skittles candy” Good indicator of IMHA Immune Mediated Hemolytic Anemia, OR AIHA Auto Immune Hemolytic Anemia. |
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Term
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Definition
| fragments of rbc’s, they look like pieces of Acanthocytes. These are cells that have been damaged in circulation. These cells have been sliced into pieces by fibrin threads. They are seen in DIC, Hemangiosarcoma, and HW disease. |
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Term
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Definition
| all that is left is the cell membrane. These cells are almost completely devoid of hemoglobin. Can be difficult to see because they are so light. |
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Term
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Definition
Areas of denatured hemoglobin. An oxidative injury has occurred.
Seen in acetaminophen (Tylenol) toxicities, onions, sardines, garlic |
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Term
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Definition
| Nuclear remnants inside the rbc’s. These are bits of the nucleus retained in the cell, after the nucleus has been extruded. Commonly seen when the cells have been rushed out of the bone marrow into circulation. A sign of regeneration, can also be a sign of lead poisoning. |
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Term
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Definition
Nucleated red blood cells- nucleus is still inside the rbc
Sign of regeneration |
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Term
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Definition
| Caused by slow drying of the slide, or cells in EDTA tube too long. |
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Term
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Definition
Disseminated Intravascular Coagulation
a disorder where proteins that control clotting are abnormally active. When a patient is in DIC, their proteins in the blood are not clotting properly. The patient can be at risk for serious bleeds from just a small injury due to the proteins not clotting as they should, or being used up. This can occur with inflammation, infection or even cancer |
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Term
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Definition
| nRBCs, HJBs, parasites, etc. |
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Term
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Definition
| coin- like stacking, Seen in horses due to the increased protein levels/ fibrinogen (stickiness) of the blood. Also seen frequently in cats, usually in thicker areas of the blood smear. |
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Term
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Definition
| clumping of blood cells. Seen in autoimmune cases. |
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Term
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Definition
Solid, no zone of central pallor
5 microns |
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Term
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Definition
disc shaped, zone of central pallor
6-7 microns |
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Term
| What are the three shapes quantitated with a percentage? |
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Definition
Spherocytes
Schistocytes
Heinz Bodies |
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Term
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Definition
Polychromasia
Anisocytosis
Howell Jolly Bodies
nRBCs |
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Term
| What is the best indicator of regeneration? |
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Definition
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Term
| How many fields should you view when evaluating RBC morphology? |
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Definition
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