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RBC Abnormalities
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15
Veterinary Medicine
Undergraduate 2
11/21/2011

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Cards

Term
Acanthocyte
Definition
(spur cell) long oddly space projections, seen in liver dysfunction and hemangiosarcoma
Term
Crenation
Definition
slide preparation artifact. too slow to dry or prolonged contact with EDTA.
Term
Echinocyte
Definition
(burr cell) short evenly spaced projections around RBC, associated with lymphosarcoma, rattlesnake bites and renal dz
Term
Leptocyte
Definition
stomatocyte is one, thin cell with more surface area, often folds onto itself
Term
Target Cell
Definition
dark center with zone around center (looks like target), seen in patients with anemia, liver dz
Term
Schistocyte
Definition
fragmented RBC due to passing through fibrinous tissue. seen in patients with DIC
Term
Spherocyte
Definition
smaller than normal RBC with no central pallor. Same volume as other RBCs (same MCV) associated with immune mediated dz
Term
Microcytosis
Definition
RBCs smaller than normal seen in Fe deficient patients
Term
Macrocytosis
Definition
Larger RBC size, seen in patients with an increased production and marrow release of immature cells
Term
Hypochromasia
Definition
Lack of pallor due to Fe deficiency
Term
Rouleaux
Definition
RBCs stacked like toppled dominoes, seen often in horses sometimes cats, idicative of inflammatory or neoplastic dz in dogs
Term
Agglutination
Definition
RBC clumping, seen in autoimmune dz and blood transfusions
Term
Howell-Jolly body
Definition
dense chromatin within RBC with a basophilic color when stained. often a response to anemia
Term
Basophilic stipling
Definition
RBC shows dots of blue stain within cell of residual RNA. common in young ruminants, cats with anemia, and Pb poisoning in dogs
Term
Heinz body
Definition
rounded "nub" on RBC due to denatured hemoglobin. due to oxidation of cell because of drugs or chemicals
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