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Pharmacology Neurology
Neurology
15
Anatomy
3rd Grade
05/14/2012

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Term
Parkinson's drugs that:
Agonize dopamine receptor
Definition
Bromocriptine
Pergolide
Pramipexole
Ropinirole
Term
Parkinson's drugs that:
Increase dopamine release from neurons
Definition
Amantadine

Also used for anti-viral against influenza
Term
Parkinson's drugs that:
Prevent Dopamine Breakdown
Definition
Selective MAO B inhibitors:
Selegiline

COMT Inhibitors:
Entacapone
Tolcapone
Term
Parkinson's drugs that:
Curb excess cholinergic activity
Definition
Antimuscarinic:
Benztropine
Term
Intravenous anesthetic:
High potency, high lipid solubility for rapid entry into the brain. Used for short surgical procedures and decreases cerebral blood flow
Definition
Barbiturates:
Thiopental
Term
Intravenous anesthetic:
Drug facilitates GABA receptor by increasing frequency of Cl channel opening
Definition
Benzodiazepines:
Midazolam
Diazepam, lorazepam, triazolam, chlordiazepoxide, alprazolam

Most commonly used for endoscopy as an adjunctive.
May cause severe post-op respiratory depression (use flumazenil as antidote)
Term
Inhaled anesthetic options
Definition
Sevoflurane
Halothane
Isoflurane
Nitrous Oxide
Enflurance

"SHINE"
Term
Intravenous anesthetic:
PCP analog that blocks NMDA receptors.
Definition
Arylcyclohexylamines:
Ketamine

Cause disorientation, hallucination and bad dreams
Term
Treatment for "Lightning pain/stabbing pain in the face" Caused my light touch or stroke.
Definition
Trigeminal neuralgia:
Carbemazepine
Term
Treatment for child that is staring off into space with a blank stare. Some smacking of the lips
Definition
Absence seizure:
Ethosuxamide

Blocks thalamic T-type Ca Channels
Term
Treatment for status epilepticus
Definition
lorazepam (ativan)

Prophylax concomitant with phenytoin
Term
Used in the treatment of malignant hyperthermia (caused by inhalation anesthetics and succinylcholine. Excess skeletal muscle contraction)
Definition
Dantrolene

Prevents the release of Ca from the sarcoplasmic reticulum of muscle
Term
Treatment for Alzheimers
Definition
NMDA Receptor antagonist:
Memantine

Acetylcholinesterase Inhibitors:
Donepezil
Galantamine
Rivastigmine
Term
Treatment for acute migraine and cluster headaches
Definition
Sumatriptan

MOA: 5HT agonist, causing vasoconstriction
Term
Glaucoma treatment options
Definition
Alpha agonists (dec aqueous humor synthesis due to vasoconstriction)

Beta Blockers:
Timolol, betaxolol (dec aqueous humor secretion)

Diuretics:
Acetazolamide (dec aqueous humor secretion due to dec HCO3)

Cholinomimetics:
Pilocarpine, pyshostigmine (inc outflow of aqueous humor, contract ciliary muscle and open trabeular meshwork

Prostaglandins:
Latanoprost (inc outflow of aqueous humor)
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