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Pathology (Lecture 2)
Pathology notes through lecture 2
50
Veterinary Medicine
Undergraduate 2
08/21/2009

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Cards

Term
What are the five cardinal signs of inflammation?
Definition
Heat, swelling, redness, pain, and loss of function.
Term
What causes the heat and redness associated with inflammation?
Definition
Vasodilatation.
Term
What causes the swelling associated with inflammation?
Definition
Decrease blood flow away from the site or edema.
Term
What is an edema?
Definition
Fluid accumulation
Term
Why is there pain associated with inflammation?
Definition
Because the swelling causes pressure of peripheral nerves silly.
Term
What factors determine the susceptibility of an individual? (4)
Definition
Age, sex, nutritional state, and amount of stress.
Term
The three lines of defense are:
Definition
Anatomic barriers, Inflammatory response/phagocytes, and Immune system.
Term
True or false: The anatomic barrier is the 2nd line of defense.
Definition
False: The anatomic barrier is the FIRST line of defense.
Term
The anatomic barrier of defense can include:(just name a few)
Definition
hair/fur (additional), mucus membranes of upper resp. system, coughing and sneezing, eyebrows, eyelids, and eyelashes, Lysozyme in tears, stomach acidity, vagina tract (secretions and acidity) and urogenital tract.
Term
Inflammation/Phagocytes are *blank* line of defense
Definition
2nd
Term
What are the first cells to respond?
Definition
Neutrophils.
Term
How long do neutrophils live once they've left the blood vessels?
Definition
24-48 hours
Term
What WBC triggers the inflammatory response?
Definition
Neutrophil.
Term
What does a neutrophil do?
Definition
Phagocytosis and releases lysosomal enzymes
Term
What does a neutrophil do?
Definition
Phagocytosis and releases lysosomal enzymes
Term
What types of inflammations would eosinophils be found in?
Definition
Parasitic and allergic
Term
What is the precursor for a macrophage?
Definition
Monocyte
Term
Define exudate
Definition
Visible product of the inflammatory process.
Term
What is a serous exudate composed of and give an example.
Definition
Fluid and protein; cutaneous blister
Term
What is a fibrinous exudate composed of (hmmmmm....I wonder) and what is an example of this exudate?
Definition
FIBRIN! Traumatic reticulopericarditis ("hardware disease)
Term
Purulent is also called...
Definition
Suppurative
Term
Purulent exudates are composed of what two things?
Definition
Large numbers of neutrophils and cellular debris.
Term
A hemorrhagic exudate is composed of what?
Definition
Erythrocytes.
Term
A patient comes in with a watery exudate coming from its eye, what type of exudate is this?
Definition
Serous
Term
A cat abscess is broken open and now there is a thick white discharge... what exudate is this?
Definition
Purulent (suppurative) ...notice how I didn't say pussy lol
Term
Eosinophilic exudates are common in what diease of pigs?
Definition
Salt poisoning.
Term
Where are you most likely to find mucopurulent exudates?
Definition
Respiratory and intestinal tracts
Term
Where can nonsuppurative exudates be found?
Definition
CNS and integument
Term
What is the thing that happens in a vascular injury (can occur in minutes)
Definition
Dilatation.
Term
What causes vascular dilatation?
Definition
Histamine
Term
What are the three vascular changes involved in inflammation?
Definition
Dilatation, vascular permeability, and influx of cells
Term
What is the end result of tissue repair?
Definition
Scarring or fibrosis.
Term
Where does fibrosis not occur?
Definition
CNS
Term
*Blank* intention healing involves a bridge formation to form a collagenous matrix to bring the edges together.
Definition
first.
Term
Granulation tissue is involved in *Blank* intention healing
Definition
second.
Term
Humoral immunity is from the *Blank* lymphocytes and cell-mediated immunity is from the *blank* lymphocytes.
Definition
B, T
Term
Which lymphocyte can live for years? (B or T)
Definition
T. B lymphocytes only survive for weeks.
Term
Which immunity produces antibodies?
Definition
Humoral
Term
What is the most common immunoglobulin?
Definition
IgG
Term
What is the 2nd most common immunoglobulin?
Definition
IgM
Term
What is IgA's function?
Definition
Mucosal immunity
Term
What is IgE associated with?
Definition
Hypersensitivity type-1 reactions and parasites.
Term
Name the four types of hypersensitivity types... not just type 1, type 2, etc...
Definition
Type 1= Immediate, Type 2= Cytotoxic, Type 3= Immune Complex, and Type 4= Delayed
Term
What could cause a type 1 hypersensitivity reaction?
Definition
Inhalation, direct contact, ingestion, bug bite or sting, or injection
Term
What are the signs of anaphylaxis?
Definition
Profound hypotension, pulmonary edema, and collapse. (+/- facial swelling and dyspnea)
Term
True or false: Type 4 hypersensitivity reactions occur within minutes.
Definition
False: Type 4(Delayed) occurs within hours. Type 1 (Immediate) occurs within minutes.
Term
What cell do all blood cells come from?
Definition
Hemocytoblast
Term
Whats are the maturation stages of an RBC?
Definition
hematocytoblast, proerythroblast, erythroblast, normoblast, reticulocyte, and erythrocyte.
Term
What are the maturation stages of thrombocytes?
Definition
hemocytoblast, megakaryoblast, megakaryocyte, thrombocyte.
Term
What is the basic maturation stages of the granularcytes?
Definition
Hemocytoblast, myeloblast, progranulocyte, myelocyte, band cell, phil.
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