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Nutrition Exam 1
Nutrition
147
Veterinary Medicine
Graduate
02/26/2013

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Cards

Term
What is the difference between Fiber and Starch related to their chemical makeups?
Definition
Fiber is beta linked and Starch is alpha linked
Term
What is the end product of Fermentation
Definition
VFA's
Term
What are examples of foregut fermenters and where does absorption occur
Definition
kangaroos, hippos; ferment in stomach o absorb in intestine
Term
What's an example of a cecal fermenter
Definition
Rabbit
Term
What's an example of a colonic fermenter
Definition
horse
Term
What's an example of a cecal-colonic fermenter
Definition
elephant or manatee
Term
What is the primary role of salivary amylase and what species lack it
Definition
starch digestion;cats and dogs
Term
What is the primary role of salivary lipase
Definition
fat digestion
Term
What are two factors that influence gastric emptying speed
Definition
stomach volume and energy content of meal
Term
How do fiber and fat affect gastric emptying?
Definition
They both slow it at higher levels
Term
What three substances are secreted in the stomach of
Definition
HCl, pepsinogen and gastric lipase
Term
What is the role of HCl
Definition
drops stomach pH so that bacteria is destroyed, hydrolyzes some proteins and saccharides and converts pepsin to pepsinogen
Term
What is the role of pepsin
Definition
helps digest protein, especialy animal protein
Term
What is the role of lipase
Definition
Acts on long chain Fatty Acids, secreted from chief cells
Term
Where does the majority of enzymatic digestion occur in autoenzymatics?
Definition
in the small intestine
Term
In what part of the GI tract are secretin and CCK released?
Definition
small intestine
Term
What are the actions of Secretin and CCK
Definition
Secretin increases bicarb secretion and CCK increases pancreatic enzyme production
Term
What does the pancreas secrete
Definition
digestive enzymes, bicarb salts, proteases, lipases, amylases
Term
Which proteases help digest proteins
Definition
trypsin and chymotrypsin
Term
What is the role of alpha amylase
Definition
breaks starch into oligo and di saccharides
Term
What is the function of the gallbladder
Definition
releases bile in response to fats in the intestines
Term
What is the function of Taurine and why is it essential in cats and not dogs
Definition
It conjugates bile acids; dogs can also use glycine for this but cats cannot
Term
what are the functions of bile
Definition
digests fats, eliminates waste, alkalinizes gastric contents and kill bacteria; without bile salts, fats will not be absorbed in the intestine
Term
How are micelles formed
Definition
bile salts aggregate around fat droplets which increases surface area for enzymatic action
Term
What are the main functions of the large intestine of autoenzymatics
Definition
electrolyte and water absorption as well as additional fermentation
Term
How long can undigested food remain in the large intestine in autoenzymatics
Definition
12 hours
Term
How are VFA's produced in the rumen
Definition
microbes convert pyruvic acid to VFA's
Term
Why do browsers have smaller rumens
Definition
eat high density, more digestible plants, dont require as much fermentation
Term
What do grazer diets consist of and how does this affect the anatomy of their GI system
Definition
Eat high fiber diets so require mroe fermentation- larger rumens and well developed omasums
Term
Hindgut fermenters have enlarged ______ and ________ for fermentation. They are ____ effective at VFA absorption.
Definition
cecum and colon; less
Term
In cecal fermenters, the hindgut secretes _______ and retains _______ for fermentation
Definition
Fiber; non fiber
Term
What is a cecotrope
Definition
feces substance produced by cecal fermenters that contains non fiber that is eaten and fermented in GI
Term
What is the main site of fermentation in colonic and ceco-colonic fermenters?
Definition
enlarged proximal colon
Term
What is dietary fiber
Definition
all plant polysaccharides and lignins that are resistant to hydrolysis by digestive enzymes of main structural carbs
Term
What are the products of carb conversion?
Definition
glucose, fructose and galactose
Term
Where are Na+ glucose transporters located?
Definition
In enterocytes and proximal tubule of kidney
Term
What are the three fates of Carbs
Definition
1. metabolized to ATP 2. stored in liver/muscle as glycogen 3. converted to FAs and stored as triglycerides
Term
What is the conversion of glucose to 2 pyruvate molecules called?
Definition
Glycolysis
Term
What is the fate of pyruvate in anaerobic glycolysis
Definition
lactate
Term
What is the end product of aerobic glycolysis
Definition
CO2 (acetyl CoA enters Krebs cycle to produce it)
Term
What is the key to making ATP
Definition
Electron Transport Chain
Term
Where is the majority of glucose stored and in what form
Definition
in liver as glycogen
Term
What substance stimulates glycogenesis
Definition
insulin
Term
Glucagon and epinephrine stimulate____
Definition
glycogenolysis
Term
What is the definition of gluconeogenesis
Definition
formation of glucose from other substrates
Term
Gross energy------Digestible energy----metabolizable energy-----new energy
Definition
lost in feces;lost in urine and gas;lost in heat from digestion
Term
Carnivores have _____________ intestinal tracts. ________ is their preferred food source and they are in a constant state of ___________
Definition
short and simple;protein;gluconeogenesis
Term
We know that cats don't ever need Carbs. When do dogs require them?
Definition
pregnancy and lactation
Term
Horses can digest ___ and ___ linked carbs with their own enzymes, but need microbes for ____ linkages
Definition
alpha 1-6 and 1-4; beta 1-4
Term
What are the main three VFAs produced in the horse
Definition
acetate, butyrate and proprionate
Term
What is the primary VFA produced in ruminants on high forage diets
Definition
acetate
Term
What is primary VFA produced in ruminants on high grain diets
Definition
proprionate
Term
The _______ is the deciding factor of what an AA is (structurally)
Definition
R-group
Term
T/F: Taurine is an AA
Definition
FALSE; its a sulfonic acid
Term
T/F: essential AAs do not need to be supplemented because the body provides them
Definition
FALSE; must be supplemented
Term
PVT TIM HALL
Definition
phenylalanine, valine, threonine, tryptophan, isoleucine, mehtionine, histidine, arginine, leucine and lysine
Term
Dispensible AAs are adequately synthesize in the body if enough __ and __ are available
Definition
N and C
Term
Which type of AA's are the most important for muscles
Definition
branched chain
Term
Methionine is the precursor of ______
Definition
Cysteine
Term
T/F: there are higher cysteine/methionine amounts in plant based diets than other diets
Definition
False
Term
What is the most common AA deficiency
Definition
Cysteine/methionine
Term
What does a deficiency in cysteine/methionine cause?
Definition
necrotic, hyperkeratotic foot pads, necrolytic dermatitis
Term
T/F: light colored animals require more phenylalanine for melanin than dark colored ones
Definition
false; black-coated animals require 2x as much
Term
What are the signs of phenylalanine/tyrosine deficiency
Definition
faded, discolored coat, may have neuro signs
Term
Lysine deficiency is common in diets that are low in ______ and mostly made of _____
Definition
protein;cereals
Term
Depression and decreased food intake are signs of a deficiency in _______
Definition
Lysine
Term
What is the name of the reaction that destroys Lysine with heat
Definition
Maillard
Term
Deficiency in _____ can lead to DCM and retinal degeneration in cats
Definition
taurine
Term
Ruminants are able to obtain exogenous protein from _______ or _________
Definition
diet; microbes in rumen
Term
Why is Urea sometimes supplemented in ruminants
Definition
Can be used by microbes to synthesize proteins
Term
What are signs of urea toxicity
Definition
tremors, salivation, tachypnea, tetany, death
Term
Which type of FAs have no double bonds, straight structures, are tightly packed and can cause artherosclerosis
Definition
saturated
Term
Describe unsaturated FAs
Definition
at least one double bond, bent structure, fluid, not tightly packed
Term
Omega 3 FAs are beneficial because they have __________ action. (THREE LETTERS)
Definition
anti-inflammatory
Term
Omega 6 FAs are ____-inflammatory
Definition
PRO
Term
T/F: Dogs cannot make arachadonic acid
Definition
FALSE; cats cant
Term
How are fast digested and transported
Definition
TG--FFAs and monoglycerides
FA emulsified with bile salts--micelles
absorbed across intestines
reform TGs--chylomicrons
Chylomicrons-- lymphatics--FFAs and glycerol at capillary endothelium
Term
FAs are oxidized through what system?
Definition
Citric Acid Cycle
Term
What is used for transport of FA in mitochondria
Definition
carnitine
Term
Carnitine deficiency in cats and dogs can result in______
Definition
DCM-- less Fas enter heart muscle
Term
What is the main energy source of the heart?
Definition
FAs
Term
What type of lipids are mobilized during starvation?
Definition
Neutral fat, which is stored in adipose tissue
Term
What type of lipids pose greatest risk of fat emboli if they circulate
Definition
plasma lipids
Term
How are TGs removed from chylomicrons?
Definition
by lipoprotein lipase
Term
What lipoprotein breaks down VLDL into FFAs and glycerol
Definition
LPL
Term
TGs are deposited into tissue by this lipoprotein
Definition
VLDL
Term
What do VLDLs become after TG are removed by LPL
Definition
IDL
Term
What is action of IDL?
Definition
removes cholesterol esters from HDL via LCAT and becomes LDL
Term
Why do dogs and cats have high levels of HDL
Definition
they lack LCAT
Term
What deposits cholesterol into peripheral tissues
Definition
LDL
Term
What transports cholesterol from tissue to liver
Definition
HDL
Term
This essential fatty acids is required only by cats
Definition
arachadonic acid
Term
Linoleic acid is an essential fatty acid that is found in ____ or _____
Definition
veggie oils or animals raised in LA plants
Term
What is the preferred source of energy in skeletal muscle? what are other options?
Definition
FFAs; glucose, FAs, ketones, branched chain AAs
Term
In extreme conditions, some parts of the brain can use ___ and ___ for energy
Definition
lactate and ketones
Term
Which two organs perform gluconeogenesis
Definition
kidney and liver
Term
The _______ utilizes most of its own glucose production
Definition
kidney
Term
The GI tract uses _% of resting oxygen consumption
Definition
20
Term
What are the main energy sources for the GI tract
Definition
glutamate and glutamine
Term
Where do colonocytes get their energy
Definition
butyrate- fermentation
Term
What are the tissues that ONLY used glucose
Definition
RBCs, retina, renal medulla
Term
During the absorptive phase, what does glucose do?
Definition
goes into circulation and/or is stored as glycogen
Term
During absorption, FFAs are____ and glucose is ____
Definition
low;high
Term
In the post-absorptive phase, the body relies on ________ energy and _________ is occuring
Definition
endogenous;glycogenolysis
Term
____________ occurs 24 hours post absorption
Definition
gluconeogenesis
Term
Where are FAs converted to ketones?
Definition
liver
Term
During stress starvation, _______ and ______ are altered which increases metabolic rate.
Definition
cytokines and hormones
Term
Increased gluconeogenesis in stress starvation leads to what issues?
Definition
slowed wound healing, impaired immunity, decreased strength, poor prognosis
Term
Vit B1 is_____. What are signs of deficiency?
Definition
Thiamin; anorexia, neuro, weakness,death. polioencephalomalacia in ruminants
Term
B12 is ________
Definition
Cobalamin
Term
What are two causes of B12 deficiency and what are the signs
Definition
bacterial overgrowth and breed (Giant shnauzer); weight loss, diarrhea, vomiting, megalo anemia
Term
Folic Acid deficiency can cause what
Definition
megalo anemia and birth defects
Term
Most animals synthesize________ from glucose. which can't?
Definition
Vitamin C (ascorbic acid); guinea pigs and some birds
Term
Vitamin C is a ____ factor that aids in synthesis of what
Definition
redox; bile acids, collagen, etc
Term
T/f: Vitamin C deficiency is not prevalent in vet med
Definition
true
Term
Vitamin A orginates from______ and cats can't convert them
Definition
carotenoids
Term
Where is Vitamin A stored
Definition
Liver
Term
What are functions of Vitamin A
Definition
vision, growth, immune function
Term
Deficiency of Vit. A causes what effects?
Definition
dogs: KCS, skin issues Cats: photophobia and maybe hyperplasia of C1-3horses: night blindness and repro failure cows:blindness
Term
Which Vitamin toxicity is teratogenic in horses, dogs and cats
Definition
Vitamin A
Term
Vitamin A toxicity causes______in cows
Definition
osteolysis and bone fragility
Term
Osseocartilagenous hyperplasia of C1-C3 in cats so they can't turn their head occurs due to toxicity of what?
Definition
Vitamin A
Term
T/F: cats and dogs DONT synthesize Vitamin D but horses and cows DO
Definition
TRUE
Term
What is function of Vitamin D
Definition
calcium and phosphorus homeostasis
Term
Lameness and rickets are common signs of what deficiency
Definition
Vitamin D
Term
Toxic levels of Vitamin D can cause_____
Definition
hypercalcemia
Term
Vitamin E functions:
Definition
antioxidant and free radical reductant
Term
What deficiency causes white muscle disease in horses and nutritional myopathy in ruminants
Definition
Vitamin E
Term
What vitamin is most associated with clotting issues
Definition
Vitamin K
Term
Which is the most prevalent mineral
Definition
Calcium
Term
When is the highest need for calcium
Definition
during bone and tooth formation
Term
What does a calcium deficiency lead to
Definition
nutritional secondary hyperparathyroidism
Term
What does calcium toxicity cause
Definition
soft tissue calcification
Term
Which is the second most prevalent mineral
Definition
phosphorus
Term
Phosphorus deficiency
Definition
poor growth, osteomalacia, hemolytic anemia
Term
phosphorus toxicity
Definition
reduce Ca absorption, urinary calculi in ruminants
Term
Which micromineral deficiency causes white muscle disease in ruminants
Definition
selenium
Term
selenium toxicity causes:
Definition
blind, staggers death in horses,; poor growth, tetanus and spasms in ruminants
Term
Definition of Calorie
Definition
amount of heat needed to raise 1 gram of water from 14.5 to 15.5
Term
What is the thermoneutral zone
Definition
temperature at which body exerts little energy in order to maintain normal temp
Term
Atwater factors:
Definition
1g protein:4 kcal
1g Carb: 4 kcal
1g fat: 9 kcal
Term
What is respiratory quotient
Definition
ratio of CO2 produced:O2 consumed
Term
RER=
Definition
BW^.75*70
Term
How to calculate DER
Definition
Life stage factor * RER
Term
When animals in ICU you should feed ______
Definition
RER
Term
What are two factors that determine energy needs
Definition
signalment and physiologic factors
Term
When calculating how much to feed, you should use the RER of what weight?
Definition
Ideal, not current
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