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Nervous II & Endocrine System
neurotransmitters, ANS, reflex, brain, endocrine
76
Anatomy
Undergraduate 2
03/06/2014

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Term
What are the two classes of neurotransmitters?
Definition
excitatory & inhibatory
Term
What do excitatory neurotransmitters do?
Definition
-cause Na influx, AP travels through postsynaptic membrane
Term
What do inhibitory neurotransmitters do?
Definition
-hyperpolarize postsynaptic membrane
-membrane potential is decreased, Cl- moves in K+ moves out
-inside of cell becomes more negative
Term
Is acetyl choline excitatory or inhibitory?
Definition
excitatory between somatic motor neurons & muscles
inhibitory between neurons & heart
Term
Give an example of inhibitory neurotransmitters
Definition
GABA
glycine
acetyl choline
Term
Give an example of excitatory neurotransmitters
Definition
acetyl choline
epinephrine
norepinephrine
dopamine
Term
What happens if a neurotransmitter remains in synapse?
Definition
Continuous stimulation of post synaptic receptor (generation of AP's)
Term
How is Ach released from the postsynaptic membrane?
Definition
Achase breaks down Ach, components are reabsorbed by synaptic knob & re-synthesized into Ach
Term
How is norepinephrine released from the postynaptic membrane?
Definition
released by the receptor, picked up by the synaptic knob, broken down
Term
What regulates the autonomic nervous system?
Definition
it is self-regulating
Term
Where does the sympathetic nervous system originate from?
Definition
thoracic & abdominal regions of spinal cord
Term
Where does the parasympathetic nervous system originated from?
Definition
the brain & pelvic regions of spinal cord
Term
Which classes of vertebrae is the ANS involved with?
Definition
thoracic, lumbar & sacral
Term
What is the preganglionic neuron?
Definition
1st neuron of efferent nerves in SYM & PARA
-carries impulse to ganglia
Term
What is the postganglionic neuron?
Definition
2nd neuron of efferent nerves in SYM & PARA
-carries impulse from ganglia to target organ
Term
Where is the cell body of the 1st neuron found?
Definition
in the brain or spinal cord
Term
What does the preganglionic neuron synapse with?
Definition
-the sympathetic chain
or
-passes through chain & synapses with a ganglion outside the chain
Term
Describe the length of post- & pre-ganglionic neurons in the SYM & PARA NS
Definition

SYM: short pre long post

PARA: long pre short post

Term
What system deals with emergency situations?
Definition
sympathetic nervous system
Term
What are some changes that occur in the body when the sympathetic nervous system is active?
Definition
bronchodilation (increase gas exchange)
increased heart rate (increase O2 delivery)
dilate arterioles (increase O2 delivery)
dilate pupils (light & peripheral vision)
reduce blood flow to GIT, skin, kidneys (not necessary in emerg.)
decreased GIT activity (not needed in emerg.)
Term
What is the key neurotransmitter in the sympathetic nervous system
Definition
norepinephrine
Term
What neurons release norepinephrine?
Definition
adrenergic neurons
Term
What neurons release Ach?
Definition
preganlionic neurons
Term
Where are alpha adrenergic receptors found? What is their function?
Definition
blood vessels
-vasoconstriction of skin, GIT & kidneys
Term
What is the function of B1 andrenergic receptors?
Definition
increase heart rate & force of contraction
Term
What is the function of B2 andrenergic receptors?
Definition
bronchodilation
Term
What is the function of the parasympathetic nervous system?
Definition
-decrease excitatory effect of fight/flight
-allow body to replenish stores
-return body to homeostasis
Term
True or False

PARA has little effect on blood vessels?
Definition
True

Except blood vessels in the GIT
Term
What neurotransmitter is released by PARA?
Definition
acetylcholine
Term
What are reflexes? What are the two types?
Definition
rapid automatic responses to protect the body
-somatic & autoomic
Term
What do somatic reflexes do?
Definition
contract skeletal muscle
Term
What do automatic reflexes do?
Definition
regulate smooth muscle, cardiac muscle, endocrine glands
Term
What is the origin of a reflex? Describe the process briefly
Definition
a sensory receptor
-receptor is stimulated to threshold, AP travels along sensory neuron, terminates in grey matter of SC or brain
Term
What happens after an AP has reached the CNS grey matter?
Definition
-information is integrated with impulses from other neurons
-integrated response is sent from SC or brain by the motor neuron to the target tissue
Term
Describe the stretch reflex
Definition
-muscle spindle stretches, impulse send via afferent neuron to SC
-sensory neuron synapses with motor neuron at SC
-stimulation of efferent motor neuron causes contraction
Term
Describe the stretch reflex caused by tapping on the patellar tendon
Definition
-quad muscle is stretched, reflex arc is stimulated, quadricep contracts, lower leg extends (kicks)
-afferent neuron also sends impulse that causes a 2nd reflex arc so the opposing muscles relax
-cerebellum is simultaneously informed of what is going on
Term
What are the 4 different sections of the brain?
Definition
cerebrum
cerebellum
diencephalon
brain stem
Term
What region of the brain is responsible for the highest order functions & behaviours?
Definition
cerebrum
Term
What are the functions of the cerebrum?
Definition
-receiving & processing sensory info
-initiate conscious nerve impulses
-integration of neuron activity for conscious activity
-reason & planning
Term
Describe the structure of the cerebrum
Definition
-gyri, fissures & sulci on the brain surface
-longitudinal fissure separating L & R hemispheres
-hemispheres further divided into lobes
-outer layer is cerebral cortex
Term
What are gyri, fissures & sulci? What is the function of gyri & sulci?
Definition
Gyri: folds
Fissures: deep grooves
Sulci: Shallow grooves

-G&S increase surface area to allow large bundles of nerve cell bodies to connect with bundles of axons
Term
An impulse in the left hemisphere will cause muscle movements on the ____ side of the body
Definition
right
Term
Describe the cerebral cortex
Definition
-outer 6 layers of neurons
-made of grey matter
-mainly nerve cell bodies which receive info from all around the body via the CNS
Term
Describe the region below the cerebral cortex
Definition
-white matter dominated by axons
-nerve fibers linking different regions f the cortex & connect it to other parts of the brain & SC
Term
What is the basal ganglion?
Definition
-pools of neurons controlling semivoluntary movements e.g. walking & running
-initiation & maintenance of normal motor activity
Term
Describe the position of the cerebellum relative to the cerebrum
Definition
Posterior/Caudal
Term
What is the function of the cerebellum?
Definition
-coordinates motor activity
-compares the intent of the body w/ actual position
-fine tunes movements
Term
What is the diencephalon, and what are its 3 major structures?
Definition
-NS passageway btwn cerebrum & primitive brain stem

Thalamus, Hypothalamus, Pituitary Gland
Term
What is the function of the thalamus
Definition
relay station, transferring sensory info from all over body to the cerebrum
Term
What is the function of the hypothalamus
Definition
interface between NS & endocrine system
integrates functions of ANS
-stimulate release of hormones to respond to temperature, hunger, thirst, rage, anger, stress, blood pressure, reproductive system etc
Term
Does the hypothalamus have PARA or SYM components?
Definition
both
Term
What is the function of the pituitary gland?
Definition
master gland of the endocrine system
regulates hormone production & secretion
Term
What is the most primitive part of the brain?
Definition
brain stem
Term
Waht is the function of the brain stem
Definition
-connects rest of brain to spinal cord
-maintains basic support functions of body
heart rate, contractions, respiration, vasoconstriction, swallowing, vomiting, coughing, sneezing
Term
What are the components of the brain stem?
Definition
Medulla Oblongata
Pons
Midbrain
Term
What is the tissue surrounding the brain & spinal cord?
Definition
meninges
Term
What is the function of the meniges
Definition
Cover & protect CNS, provide nutrients & oxygen to the superficial layers off brain & SC
Term
Describe the 3 layers of the meniges
Definition
Dura mater: outer ayer, tough, fibrous
Arachoid: delicate & spider web like
Pia mater: inner thin, lies directly on brain & SC
Term
What is the function of cerebrospinal fluid
Definition
-protects CNS from the surfaces of skull & vertebral column
-minimize displacement of brain
-maintain external environment for brain cells
-route for removing metabolites from brain
Term
What is cerebrospinal fluid derived from?
Definition
blood plasma
Term
What is the structure & function of the blood-brain barrier
Definition
-separates brain capillaries from nervous tissue
-not porous, prevents ions, drugs etc from reaching brain
Term
What are astrocytes?
Definition
specialized glial cells which selectively transport materials into the brain
Term
When does the brain stem become the spinal cord?
Definition
at the foramen magnum
Term
What is the function of the spinal cord?
Definition
-conduct sensory info & motor instructions
-process/modify impulses between brain & peripheral nerves
Term
What 2 systems are involved with coordination & control of tissue & organs?
Definition
Nervous System
Endocrine System
Term
What is the difference between endocrine exocrine glands?
Definition
Endocrine: ductless
Exocrine: secrete through a duct
Term
True or False

All cells have receptors for all types of hormone, some are just not switched on
Definition
False

not all cells have receptors to specific hormones
Term
Describe the negative feedback system of thyroid hormone
Definition
-T3 & T3 levels in blood decrease to certain level
-pituitary detects low evels
-TSH is produced to stimulate thyroid gland
-T3 & T4 levels rise
-antuitary detects this, stops production of TSH
Term
What are the two methods of hormone secretion?
Definition
negative feedback
direct stimulation from NS
Term
Describe hormone secretion by direct stimulation from NS
Definition
-nerve impulses stimualate endocrine gland to release hormone
e.g. adrenal medulla stimulated to release catecholamines for fight/flight response
Term
Describe the position of the pituitary relative to the hypothalamus
Definition
ventral
Term
Does the hypothalamus have neurons or glands secreting hormones?
Definition
modified neurons
Term
What is another term for the pituitary?
Definition
hypophysis
Term
What is the composition & function of the anterior pituitary
Definition
-glandular tissue
-produces 7 hormones
-stimulated by hypothalamus & direct feedback
Term
What is the composition & function of the posterior pituitary
Definition
-nervous tissue
-stores & releases 2 hormones produced by hypothalamus (ADH & oxytocin)
Term
[image]
Definition
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