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Muscle
Muscle review for quiz , Proffesor Alba
18
Anatomy
Undergraduate 1
03/06/2010

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Term
Facts about Skeletal Muscle
Definition
--Each skeletal muscle is a single organ composed of skeletal muscle tissue(composed of muscle fiber.
--Each muslce is structurally organized in bundles that are separated by connective tissue sheaths.
--CT sheaths support and reinforce muscle preventing bursting during strong contractions.
Term
Gross Microscopic Anatomy: Skeletal Muscle
Definition
1.Muscle
2.Fascicles
3.Muscle Fibers(cells)
4.Myofibrils
5.Thick and thin filaments
Term
Connective Tissue Coverings
Definition
Fascia, epimysium, perimysium, endomysium
Term
Fascia
Definition
Covers the entire Muscle
Term
Epimysium
Definition
Wraps fascicular bundles
Term
Perimysium
Definition
Separates individual fasciles
Term
Endomysium
Definition
Wraps individual muscle fibers
Term
Skeletal Muscle: Innervation and Vascularization
Definition
--Uses large amounts of energy(needs constant oxygen supply and nutrients)
--Each muscle has but one nerve and artery and at least one vein
--Multiple capillaries adapted for muscle movement (look like squiggles)
Term
Skeletal Muscle Microscopic Anatomy
Definition
--Muscle fiber(is a single cell)
--Relatively large in diameter and long
--Each Muscle fiber is surrounded by sarcolemma and contains sarcoplasm.
--T tubules (sarcolemmal modifications)
--Sarcoplams contains large amounts of glycosomes, myoglobin (red, oxygen storing pigment), myofibrils and specialized sarcoplasmic reticulum.
Term
Thick Filament system: Myosin found in A Bands
Definition
The thick filament system is composed of Myosin protein which is connected from the M-line to the Z-disc by titin. It also contains myosin-binding protein C which binds at one end to the thick filament and the other to Actin.
Term
Thin filament system: Actin found in I band
Definition
The thin filaments are assembled by Actin monomers bound to nebulin, which also involves tropomyosin (a dimer which coils itself around the F-actin core of the thin filament) and troponin.
Term
I bands
Definition
Composed of thin Actin Filaments
Term
A bands
Definition
Composed of thick Myosin Filaments
Term
H Zone
Definition
Central region of the A band, where actin and myosin do NOT overlap
Term
Z line( or Z body)
Definition
In I bands, consist of proteins (Nebulin) that hold actin filament in place
Term
M line
Definition
In A bands, consist of proteins (Titin) that hold myosin filaments in place
Term
Tropomyosin Strand
Definition
Found in the thin filament, composed of Actin and it's main functions are:
-Help stiffen Actin core
-Block Actin-myosin binding sites at rest
Term
Troponin (3-polypeptide complex)
Definition
A complex of muscle proteins which, when combined with Ca++, influence tropomyosin to initiate contraction.
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