Term
| What are the two types of lymph tissue? |
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Definition
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Term
| What are the structural units of lymphoid tissues? |
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Definition
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Term
| What is the difference between dense and diffuse lymphatic tissue? |
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Definition
Dense has capsule around nodules
Diffuse is non-capsulated |
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Term
| What is the role of the lymphatic system? |
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Definition
Drain interstitial fluid
Immune defense
Transport lipid/lipid-solubles from GI tract to vascular sys |
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Term
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Definition
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Term
| A lymphoid organ is comprised of what kind of lymphatic tissue? |
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Definition
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Term
| What are the types of diffuse LT? |
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Definition
MALT-Mucus
GALT-Gut
BALT-Bronchus
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Term
| True/False: Lymph nodes are lymphoid organs |
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Definition
| True: they are capsulated |
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Term
| What types of cells predominate in the cortex of a lymph node? |
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Definition
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Term
| What types of cells predominate in para-cortex of lymph nodes? |
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Definition
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Term
| What types of cells predominate in the medulla of a lymph node? |
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Definition
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Term
| How does an activated lymph node differ from that of a non-activated one? |
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Definition
| activated lymph node has Germinal Center (zone of proliferation) |
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Term
| What is a primary nodule? |
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Definition
| A non-activated lymph node (no germinal center) |
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Term
| What is a secondary nodule? |
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Definition
an activated lymph nodule
Has Germinal center |
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Term
| Describe the path of lymph through a lymph node |
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Definition
Afferent lymph vessel->Subcapsular sinus->
trabecular sinus-> Medullary sinus->Efferent lymph vessel |
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Term
| Describe maturation of T cell in lymph nodes |
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Definition
- APC's are activated by cytokenes
- APC's migrate from Mucosal membranes to lymphnodes
- Immature T cells produced in bone marrow migrate to nodes
- T cell scan peptide carried by APC, and will proliferate, mature if recognized
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Term
| Describe how B cells fight against pathogens |
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Definition
| Divide into memory or plasma cells that produce antibodies |
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Term
| How do antibodies destroy pathogen molecules? |
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Definition
- Neutralization Cover toxic active site
- Agglutination forming clumps of pathogens
- Precipitation Clumping of anitigen molecules
- Activating complement proteins which create pores in cell-->lysis
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Term
| Which ebryonic germ layer does thymus arise from? |
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Definition
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Term
| The lobule is a structural unit of which lymphatic organ? |
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Definition
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Term
| Describe the cortex of a thymus lobule |
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Definition
No lymph nodule or plasma cells
ONLY reticular and macrophage cells |
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Term
| Which types of ERC found in cortex? |
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Definition
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Term
| What is the role of ERC I? |
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Definition
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Term
| what is the role of ERC II? |
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Definition
| separate T-cell to T-cell transmission |
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Term
| What is the role of ERC II? |
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Definition
| separates cortex from medulla (cortical side) |
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Term
| What separates the cortex from medulla of the thymus? |
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Definition
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Term
| What is the role of ERC V? |
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Definition
negative elimination
Surrounds T cells and removes those with wrong antibody |
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Term
| What is the role of ERC VI? |
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Definition
| These are dead ERC's or dying ERC's |
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Term
| What is the Hassell's Corpsucle? |
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Definition
| Aggregation of dead ERC's in the medulla |
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Term
| What are regulatory T-cells |
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Definition
| Complete negative selection of cells that get rid of faulty T-cells that have escaped thymic censorship |
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Term
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Definition
The lymphoid tissue of the spleen that surroudns vessels holding T cell
or lymphatic nodules that house B cells
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Term
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Definition
| Regions of the spleen taht house the chords of cells, reticular, plasma, macrophage and blood sinus |
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Term
| Describe the path of blood through the spleen |
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Definition
- Blood enters through central artery
- Central artery surroudned by T cell LT (PALS)
- Central artery branches and forms into sinusoids near nodule periphery
- Macrophages located just outside lymph node destroy old RBC
- Healthy RBC's collect in another sinusoid and return back to venous
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