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Lymphatic System & Immunity
Terms and facts about the Lymphatic and Immune Systems
28
Anatomy
Undergraduate 1
01/16/2012

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Term
Lymph
Definition
Fluid in the tissue spaces that carries protein molecules and other substances back to the blood. Also interstitial fluid.
Term
Lymphatic Capillaries
Definition
Lymphatic vessels; one-way movement, microscopic, one cell layer thick, poor fit between cells make porous walls, blind-end tubes in tissue spaces.
Term
Lacteals
Definition
Lymphatic vessels in the wall of the small intestine for fat transportation.
Term
Right Lymphatic Duct
Definition
Drains lymph from the right arm, right side of head, neck and upper torso.
Term
Thoracic Duct
Definition
Largest lymphatic vessel. Drains lymph from about 3/4 of the body.
Term
Cisterna Chyli
Definition
Enlarged pouch along the course of the thoracic duct.
Term
Lymphedema
Definition
Swelling(edema) of the tissues caused by blockage of lymphatic vessels.
Term
Lymphangitis
Definition
Inflammation of lymphatic vessels, may progress to septicemia (blood infection).
Term
Elephantiasis
Definition
Severe lymphedema of limbs resulting from parasite infestation of lymphatic vessels.
Term
Lymph Nodes
Definition
Located in clusters along vessel pathway. Lymph enters from several afferent vessels, exits from one efferent vessel. Filters lymph.
Term
Lymphadenitis
Definition
Swelling and tenderness of lymph nodes.
Term
Metastasis
Definition
Cancer cells can easily move through lymphatic vessels to other parts of the body.
Term
Lymphoma
Definition
Malignant tumor of lymph nodes. Hodgkin disease and non-Hodgkin lymphoma.
Term
Thymus
Definition
Lymphoid tissue organ in mediastinum. Mostly inactive in adults. Produces T cells.
Term
Spleen
Definition
Largest lymphoid organ. Located; upper left quadrant. Phagocytosis of bacteria and old RBCs, blood reservoir.
Term
Nonspecific Immunity
Definition
First line defense. Mechanical barrier to harmful agents. Ex; skin, tears, mucus, ear wax, vomitting, diarrhea.
Term
Specific Immunity
Definition
Second line defense, complement immune system, cell mediated immunity. Body can recognize, respond to, and remember harmful substances/bacteria.
Term
Inherited Immunity
Definition
Inborn immunity. Immunity to certain diseases from time of birth.
Term
Aquired Immunity
Definition
Immunity obtained after birth by injections or exposure to a harmful agent.
Term
Natural Immunity
Definition
Exposure to agent is not deliberate.
Active; active disease
Passive; immunity passes from mother to fetus through placenta or from mother to child through milk.
Term
Artificial Immunity
Definition
Exposure to agent is deliberate.
Active; vaccination, dead or weak virus
Passive; protective material developed in another's immune system then transmitted to nonimmune person.
Term
Antibodies
Definition
Protein compounds with specific binding sites that bind to specific antigens. Forms antigen-antibody complex. Humoral or antibody-mediated immunity.
Term
Antigen-Antibody Complex
Definition
1.Neutralize/inactivate toxins.
2.Clump or agglutinate cells.
3.Promote phagocytosis.
Term
Cytotoxic T Cell
Definition
Kills infected or tumor cells by releasing a substance that poisons them.
Term
Helper T Cell
Definition
Releases chemicals that attract and activate macrophages to "eat" cells; produce chemicals that help activate B cells.
Term
Regulatory T Cell
Definition
Releases chemicals to suppress immune responses.
Term
Allergy
Definition
Hypersensitivity to harmless environmental antigens(allergens).
Immediate response is usually humoral.
Delayed response is usually cell-mediated.
Term
Autoimmunity
Definition
Inappropiate, excessive response to self-antigens. Causes autoimmune disease.
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