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Lecture 08
Terms, Vocabulary & Concepts
10
Anatomy
Undergraduate 2
02/08/2012

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Term
Dermis: Papillary Region
Definition
  • Think "paipillary" - nipple, at the top
  • At the top 1/5 of the dermis, superficial
  • Comprised of:
    • Areolar connective tissue
    • Dermal papillae
    • Meissner's corpuscles
Term
Dermis: Reticular Region
Definition
  • The most basal region of the dermis, bottom 4/5 of the dermis.
  • Much thicker than the paillary region
  • Comprised of:
    • thicker things
      • Dense irregular connectie tissue
      • Thick collagen fibers/elastic fibers
    • some adipose, hair follicles
    • Pacinian corpuscles - deep pressure/vibration
Term

Dermis: Papillary Region - Meissner's Corpuscles

Definition
  • A type of mechanorecepter
  • They are unmyelinated nerve endings responsible for the the sensitivity to light touch.
  • The number of Meissner's corpuscles drops 4-fold b/t age 12 and 50. 
  • Adapt quickly but then action potentials cease
Term

Dermis: Papillary Region - Pacinian corpuscles

Definition
  • A mechanoreceptor.
  • Deeper than Meissner's corpuscles, responds to acute and depp pressure and vibrations
  • Fewer number of them than Meissner's corpuscles.
Term
Dermis: Papillary Region - Arretor Pili Muscles
Definition
  • Extends from the papillary zone to the base of a hair follicle
  • Smooth follicle.
  • Contraction of muscle causes hair to stand erect.
  • Causes goose bumps.
Term
Skin Cancer: Malignant - Anaplasia
Definition
Lace of cell differnetiation and with an increased capacity to multiply
Term
Skin Cancer - Basal Cell Carcinoma (BCC)
Definition
  • Basal - at the deepest layer
  • The least malignant and most common skin cancer (75% of all skin cancers)
  • It rarely metastasizes or kills.
  • Stratum basale cell s proliferate and invade the dermis and hypodermis.
  • Can be cured by surgical excision in 99% of the cases.
Term
Skin Cancer: Squamous Cell Carcinoma (SC)
Definition
  • Arises from keratinocytes of stratum spinosum.
  • Accounts for about 20% of all skin cancers
  • Grows rapidly and metastasizes if not rapidly
  • Arise most after on the scalp, ears, and lower lips.
  • Often hyperkeratotic, excessive growth of horny tissue (straum corneum on skin, and exphytic (growing outwards from skin) with central ulceration.
  • Prognosis is good if treated by radiation therapy or removed surgically
Term
Skin Cancer: Melanoma
Definition
  • A malignant tumor which originates in melanocytes found in the stratum basale/germinativum.
  • The majority of melanomas black or brown. However some are skin-colored, pink, red, purple, blue or white.
  • Treated by wide surgical excision accompanied by immunotherapy.
  • Chance of survival is poor if the lesion is over 4mm thick.
Term
Skin tags/Liver Spots
Definition
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