Term
|
Definition
| Have a dedicated surgical facilty |
|
|
Term
|
Definition
| Surgical facility not required |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
Wild or house mouse/selective breeding
Average adult weighs 20-40 grams
females and docile males aggressive
Temp: 99 RR: 84 - 230 HR: 328 - 780
life span 1.5 - 2.5 years
breeding onset 50 - 60 days |
|
|
Term
|
Definition
Sex by anogential distance
females have sorter distance than males |
|
|
Term
|
Definition
| Put a male near large group of females and within 72 hrs 40 - 50 % are ready to breed |
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|
Term
|
Definition
| If exposed to a male, a pregnant female will abort litter |
|
|
Term
|
Definition
Estrus every 4 days
gestation 3 weeks
Average litter size 10 - 12 pups
wean at 3 weeks |
|
|
Term
|
Definition
Large colony with random matings
swiss
swiss webster
ICR |
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|
Term
|
Definition
At least 20 consecutive broth x sister matings
Balb/c - white
C57/BL - black
C3H - dark brown
DBA - light brown
SCID - white
nude - nude |
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|
Term
|
Definition
| Offspring of 2 lines of inbred parents |
|
|
Term
|
Definition
| Genetic material introduced from one animal into fertilized egg of a different animal |
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|
Term
|
Definition
| animal that has a gene removed or blocked |
|
|
Term
|
Definition
Have associated known microflora
|
|
|
Term
| Mouse Injections and Blood |
|
Definition
0.2 - 0.3 ml of blood
2 ml parentineal
2.5 SC |
|
|
Term
| Specific Pathogen Free (SPF) |
|
Definition
| Free of specific pathogens |
|
|
Term
| Conventional Rearing (CV) |
|
Definition
|
|
Term
|
Definition
| Free of all detectable microflora |
|
|
Term
|
Definition
Brown Norway rat in Eastern Asia
first mammal to become domesticated primarily for research
avg male - 500g avg female - 350g
temp: 99.5 RR: 66-114 HR: 260-600
life span 3 yrs |
|
|
Term
|
Definition
estrus 5 days
gestation 21 days
litter size 8 - 12 pups
mature at 7 weeks |
|
|
Term
| Rat Injections and Blood Draw |
|
Definition
7% of weight in blood draw - 2-3 mls total
SC - 2 mls
IP - 2 mls
IV - 0.5 mls |
|
|
Term
|
Definition
| Any strains separated after 8-19 generations and maintained without further inter crossing for 12 or more generations |
|
|
Term
|
Definition
| 2 strains genetically identical except for a difference at a single locus |
|
|
Term
|
Definition
| Strain developed by repeated back crossing minimum of 10 back cross generations to the background strain |
|
|
Term
|
Definition
| Inbreeding with forced heterozygosis |
|
|
Term
|
Definition
| Strains formed by crossing 2 inbred strains followed by 20 or more generations of brother x sister matings |
|
|
Term
|
Definition
|
|
Term
|
Definition
Sister and sprague dawley
long Evans
|
|
|
Term
|
Definition
|
|
Term
|
Definition
Murine Resp Mycoplasmosis (MRM)
Tyzzer's Disease - caused by clostridium
Mouse Parvovirus - MPV
Sendai Virus
Mouse Hepatits - MHV
Lymphocytic Choriomeningitis - LCM - Zoonotic |
|
|
Term
|
Definition
Mites - myopia and mycoptes
Pinworms - syphacia and Aspicularis
Lice - polyplax |
|
|
Term
|
Definition
|
|
Term
| Infectious Diseases of Rats |
|
Definition
MRM
Tyzzers
Salmonella
CARB
SDAV
Lepto |
|
|
Term
|
Definition
Mites - radfrodia ensifera
pinworms
lice
tapeworms - rodentolepis nana
Dermatophytosis |
|
|
Term
|
Definition
Fasting not required
ketamine can cause muscle damage and nerve irritation
rodents are prone to hypothermia
place on dry paper towel to recover |
|
|
Term
|
Definition
Co2 chamber
cervical dislocation
bilateral numothorax
hypothermia
decapitation |
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|
