| Term 
 
        | The nervous system is divided into what two parts? |  | Definition 
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        | Term 
 
        | afferent fibers send a signal which direction |  | Definition 
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        | Term 
 
        | efferent fibers send a signal which direction |  | Definition 
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        | Term 
 
        | Peripheral nervous system has what divisions |  | Definition 
 
        | somatic nervous system, autonomic nervous system |  | 
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        | Term 
 
        | the autonomic nervous system has what two divisions |  | Definition 
 
        | sympathetic, parasympathetic |  | 
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        | the CNS is composed of what 5 major subdivisions |  | Definition 
 
        | spinal cord, brainstem, cerebellum, diencephalon, cerebrum |  | 
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        | Term 
 
        | what is the cerebrum derived from |  | Definition 
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        | what constitutes the majority of the weight of the brain and occupies most of the skull |  | Definition 
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        | what structure lies above the brain stem |  | Definition 
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        | what does the diencephalon consist of |  | Definition 
 
        | thalamus, hypothalamus, epithalamus |  | 
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        | what does the brain stem consist of? (3) |  | Definition 
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        | lower end of the brainstem continues as what |  | Definition 
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        | structure which lies inferior to the cerebrum and posterior to the brain stem |  | Definition 
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        | Term 
 
        | include all nerve tissue other than the brain and spinal cord |  | Definition 
 
        | peripheral nervous system |  | 
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        | Term 
 
        | a spinal nerve has two points of attachment to the spinal cord, what are they and what are their roles |  | Definition 
 
        | posterior (sensory), anterior (motor) |  | 
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        | Term 
 
        | how many pairs of nerves are there |  | Definition 
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        | where does the spinal cord terminate |  | Definition 
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        | Development of the neural plate begins when |  | Definition 
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        | Term 
 
        | What gives rise to the CNS |  | Definition 
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        | Term 
 
        | initially, the CNS appears as a thickening of ectoderm called the.... |  | Definition 
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        | Term 
 
        | the neural plate extends towards what |  | Definition 
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        | Term 
 
        | later, the lateral edges of the neural plate become elevated to form what |  | Definition 
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        | Term 
 
        | the lateral edges of the neural plate become elevated to form the neural folds, leaving the depressed midregion to form what |  | Definition 
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        | Term 
 
        | as the neural folds approximate in the midline what happens |  | Definition 
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        | Term 
 
        | where does fusion of the neural folds start? |  | Definition 
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        | Term 
 
        | fusion of the neural folds begins in the cervical region and proceeds in which direction |  | Definition 
 
        | cephalic, caudal directions |  | 
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        | Term 
 
        | the complete fusion of the neural folds results in what |  | Definition 
 
        | formation of the neural tube |  | 
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        | Term 
 
        | each end of the neural tube remains temporarily open in connection what what |  | Definition 
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        | Term 
 
        | the neural tube remains temporarily open with the amniotic cavity by way of what? |  | Definition 
 
        | anterior and posterior neuropores |  | 
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        | Term 
 
        | Which neuropore closes first |  | Definition 
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        | Term 
 
        | after closure of the neuropores, the CNS forms a closed tubular structure with a narrow caudal portion, and a broader cephalic portion.  What is the narrow caudal portion? |  | Definition 
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        | Term 
 
        | after closure of the neuropores, the CNS forms a closed tubular structure with a narrow caudal portion, and a broader cephalic portion.  What is the broader cephalic portion? |  | Definition 
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        | Term 
 
        | during development and after closure of the neural tube, what cells rapidly divide and proliferate? |  | Definition 
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        | Term 
 
        | when the neural tube closes, neuroepithelium gives rise to what cell |  | Definition 
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        | Term 
 
        | neuroblast cells will later form what layer |  | Definition 
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        | Term 
 
        | neuroblast cells eventually form the mantle layer.  the mantle layer differentiates into what |  | Definition 
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        | Term 
 
        | During the development of the spinal cord, what is the outermost layer |  | Definition 
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        | Term 
 
        | what layer contains nerve fibers emerging from the neuroblasts in the mantle layer? |  | Definition 
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        | Term 
 
        | the marginal layer will later become what |  | Definition 
 
        | white matter of the spinal cord |  | 
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        | Term 
 
        | what are the 3 primary brain vesicles |  | Definition 
 
        | prosencephalon, mesencephalon, rhombencephalon |  | 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
 | 
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        | Term 
 
        | what are the 2 flexures of the cephalic end of the neural tube |  | Definition 
 
        | cervical flexure, cephalic flexure |  | 
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        | Term 
 
        | where is the cervical flexure located |  | Definition 
 
        | junction of hindbrain and spinal cord |  | 
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        | Term 
 
        | where is the cephalic flexure located |  | Definition 
 | 
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        | Term 
 
        | what are the 2 parts of the prosencephalon |  | Definition 
 
        | telencephalon, diencephalon |  | 
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        | Term 
 
        | primitive cerebral hemispheres aka |  | Definition 
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        | Term 
 
        | 2 parts of the rhombencephalon |  | Definition 
 
        | metencephalon, myelencephalon |  | 
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        | Term 
 
        | what part of the rhombencephalon will later form the pons and cerebellum |  | Definition 
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        | Term 
 
        | origin, differenetiation, development of skeletal muscles |  | Definition 
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        | Term 
 
        | what does skeletal muscle arise from |  | Definition 
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        | Term 
 
        | differentiation of muscle involves changes in what (3) |  | Definition 
 
        | structure, biochemistry, excitability |  | 
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        | Term 
 
        | Myogenesis: What are the 3 major stages prior to innervation |  | Definition 
 
        | myoblast, myotube, myofiber |  | 
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        | Term 
 
        | what are progenitors of skeletal muscle called |  | Definition 
 | 
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        | Term 
 
        | function of presumptive myoblasts |  | Definition 
 
        | synthesize DNA, divide mitotically, are mononuclated |  | 
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        | Term 
 
        | what do presumptive myoblasts need to do in order to be referred to as just myoblasts |  | Definition 
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        | Term 
 | Definition 
 
        | mononucleated, capable of fusing |  | 
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        | Term 
 
        | major difference between presumptive myoblasts and myoblasts |  | Definition 
 
        | myoblasts cease synthesizing DNA |  | 
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        | Term 
 
        | what do myoblasts begin to synthesize instead of DNA |  | Definition 
 | 
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        | Term 
 
        | what is the first contractile filament to appear on the periphery of myoblasts |  | Definition 
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        | Term 
 
        | after actin appears on the periphery of the myoblast, what appears in the interior of the cell |  | Definition 
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        | Term 
 
        | how are myosin and actin synthesize during myogenesis |  | Definition 
 
        | independently of each other |  | 
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        | Term 
 
        | Myoblasts become myotubes when: 1 |  | Definition 
 
        | myofilaments become prominent |  | 
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        | Term 
 
        | Myoblasts become myotubes when: 2 |  | Definition 
 
        | myoblasts fuse with other myoblasts |  | 
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        | Term 
 
        | Myoblasts become myotubes when: 3 |  | Definition 
 
        | myoblast fusion causes the new cell to become multinucleated |  | 
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        | Term 
 
        | Myoblasts become myotubes when: 4 |  | Definition 
 
        | nuclei are centrally located and actin/myosin are located in periphery |  | 
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        | Term 
 
        | fusion of mybolsts into myotubes triggers many changes within the cell, such as (2) |  | Definition 
 
        | structure and enzyme composition |  | 
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        | Term 
 
        | fusion of myoblasts into myotubes triggers many changes in the membrane, such as (2) |  | Definition 
 
        | electrical and chemical excitability |  | 
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        | Term 
 
        | What is chemical excitablity |  | Definition 
 
        | insertion of membrane protein molecules that later become chemically gated channels |  | 
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        | Term 
 
        | chemical excitability is endowed by what |  | Definition 
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        | Term 
 
        | what opens cholinergic receptors |  | Definition 
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        | Term 
 
        | When AcH activates cholinergic receptors, what happens |  | Definition 
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        | Term 
 
        | What occurs when maturation of myotubes occurs? (2) |  | Definition 
 
        | sacroplasmic reticulum form, T-tubules and terminal cisternae form |  | 
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        | Term 
 
        | myotubes progress to become myofibers when (2) |  | Definition 
 
        | nuclei are pushed peripherally and actin/myosin are centralized |  | 
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        | Term 
 
        | What happens to the resting membrane potential when myoblasts progress into myotubes |  | Definition 
 
        | decrease in potential, ie -10 to -50 mV |  | 
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        | Term 
 
        | Myofibers will not become a mature, functional muscle fibers unless what |  | Definition 
 | 
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        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | early stages of synaptogenesis include what (3) |  | Definition 
 
        | adhesion between 2 cells, establishment of functional interactions, occurence of ultra structural changes |  | 
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        | Term 
 
        | after a neuron has reached its final resting position, what begins |  | Definition 
 | 
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        | Term 
 
        | one motor neuron innervates many muscle cells to form what |  | Definition 
 | 
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        | Term 
 
        | What 4 factors that effect how growth cones reach their targets? |  | Definition 
 
        | contact-mediated attraction, contact-mediated repulsion, chemoattraction, chemorepulsion |  | 
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        | Term 
 | Definition 
 | 
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        | Term 
 
        | neural groove becomes what |  | Definition 
 | 
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        | Term 
 
        | the growth cone phase of synaptogenesis is characterized by what |  | Definition 
 
        | producing new membrane and synthesizing proteins |  | 
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        | Term 
 
        | the bouton phase of synaptogenesis is characterized by what |  | Definition 
 
        | synthesizing Ach instead of proteins and producing new membrane |  | 
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        | Term 
 
        | mature pre-synaptic endings store, package, and release what? |  | Definition 
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        | Term 
 
        | How do presynaptic vesicles release Ach: In the resting presynaptic bouton, vesicles are anchored to what |  | Definition 
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        | Term 
 
        | How do presynaptic vesicles release Ach: in the resting presynaptic bouton, vesicles are anchored to the cytoskeleton, the membrane is impermeable to what |  | Definition 
 | 
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        | Term 
 
        | How do presynaptic vesicles release Ach: Depolarization causes the botoun to what |  | Definition 
 | 
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        | Term 
 
        | How do presynaptic vesicles release Ach: Depolarization causes the bouton to become permeable to Ca+2 allowing the vesicles to do what |  | Definition 
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        | Term 
 
        | Later, mature post synaptic elements synthesize what |  | Definition 
 | 
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        | Term 
 
        | What are the 3 changes that occur in muscle cell secondary to innervation |  | Definition 
 
        | redistribution of Ach receptors, formation of an endplate, Acetylcholinesterase synthesis |  | 
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        | Term 
 
        | Nerves release what on muscle cells throughout life to ensure the health of the muscle |  | Definition 
 | 
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        | Term 
 
        | After a nerve synapses with a muscle cell, what begins to form |  | Definition 
 
        | nerve begins to form dendrites |  | 
        |  | 
        
        | Term 
 
        | The muscle sends the nerve a message to begin to form dendrites via what |  | Definition 
 
        | retrograde axonal transmission |  | 
        |  |