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intro to tissues
lecture 9/20/11
66
Anatomy
Undergraduate 1
09/20/2011

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Term
4 Types of tissues:
Definition
Epithelial tissue
Connective tissue
Muscle tissue
Nerve tissue
Term
Epithelial tissue:
Definition
Forms boundaries between different
environments, protects, secretes, absorbs, filters
• Skin surface (epidermis)
• Lining of GI tract organs and other hollow organs
Term
Connective tissue:
Definition
Supports, protects, binds
other tissues together
• Bones
• Tendons
• Fat and other soft padding tissue
Term
Nervous tissue:
Definition
Internal communication
• Brain, spinal cord, and nerves
Term
Muscle tissue:
Definition
Contracts to cause movement
• Muscles attached to bones (skeletal)
• Muscles of heart (cardiac)
• Muscles of walls of hollow organs (smooth)
Term
Epithelial Tissue; Two main types (by location):
Definition
Covering and lining epithelia
On external and internal surfaces
Glandular epithelia
Secretory tissue in glands
Term
Characteristics of Epithelial Tissue:
Definition
Cells have different functions on different surfaces
* apical (upper, free)
* basal (lower, attached) surfaces
Apical surfaces may bear microvilli or cilia
Noncellular basal lamina of glycoprotein and collagen lies adjacent to basal surface
Term
2 sides of epithelial tissue
Definition
apical; upper or free; may have microvilli or cilia
basal; lower, attached
Term
Characteristics of Epithelial Tissue:
Definition
Are composed of closely packed cells
Continuous sheets held together by tight junctions and desmosomes
Supported by a connective tissue reticular lamina (under the basal lamina)
Avascular but innervated
High rate of regeneration
Term
Four classes of connective tissue
Definition
Connective tissue proper
Cartilage
Bone
Blood
Term
Hyaline
Definition
denotes a substance with a glass-like appearance.
Term
Connective tissue
Definition
Most abundant and widely distributed tissue type
Term
collagen
Definition
is a group of naturally occurring proteins found in animals, especially in the flesh and connective tissues of mammals.
Term
matrix
Definition
a formative part, as the corium beneath a nail;
the intercellular substance of a tissue.
Term
Connective tissue proper
Definition
a fibrous tissue;It has 3 main components; cells, fibers, and extracellular matrix.
Term
cartilage
Definition
a flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.
Term
Functions of connective tissue
Definition
Binding and support
Protection
Insulation
Transportation (blood)
Term
Connective tissues have:
Definition
Same origin – Mesenchyme tissue
Varying degrees of vascularity
Term
Mesenchyme tissue
Definition
) the meshwork of embryonic connective tissue in the mesoderm from which are formed the connective tissues of the body and the blood and lymphatic vessels.
Term
3 Kinds of muscle tissue
Definition
Skeletal muscle
Mechanical Energy – attached to bone or skin
Cardiac muscle
automated - in heart only
Smooth muscle
Automated – in walls of hollow organs
Term
smooth muscle
Definition
digestive tract, veins arteries
Term
cardiac muscle
Definition
striations and Intercalated discs
uninucleate; branched
Term
Skeletal –
Definition
straitions
Contractile units
multinucleate
Term
Special Characteristics of nervous tissue
Definition
Irritable tissue
Transmits electrical energy
RMP is essential!
Term
LAYERS means
Definition
stratified
Term
"simple" epithelium
Definition
single layer
Term
3 types of epithelia
Definition
squamous
cuboidal (pseudo & regular)
columnar
Term
Endothelium
Definition
The lining of lymphatic vessels, blood vessels, and heart
Term
Mesothelium
Definition
The epithelium of serous membranes in the ventral body cavity
Term
describe Transitional epithelium
Definition
Resembles both
stratified squamous and stratified
cuboidal; basal cells cuboidal or
columnar; surface cells dome
shaped or squamouslike, depending
on degree of organ stretch.
Term
exocrine glands
Definition
have ducts (endocrine glands don't)more numerous than endocrine glands
Term
What is a gland?
Definition
A gland is one or more cells that makes and secretes an aqueous fluid
Term
unicellular gland :
Definition
the goblet cell
Term
Multicellular exocrine glands are composed of
Definition
a duct and a secretory unit
Term
Multicellular exocrine glands are classified by:
Definition
Duct type (simple or compound)
Structure of their secretory units (tubular, alveolar, or tubuloalveolar)
Term
serous membranes (internal)
Definition
line and enclose several body cavities, known as serous cavities, where they secrete a lubricating fluid which reduces friction from muscle movement.
Term
Special Characteristics of CT
Definition
Varying degrees of vascularity
Cells separated by nonliving extracellular matrix (ground substance and fibers)
Term
Structural Elements of Connective Tissue
Definition
ground substance
collagen fibers
cells
Term
Three types of CT fibers
Definition
Collagen (white fibers)
Strongest and most abundant type
Provides high tensile strength

Elastic
Networks of long, thin, elastin fibers that allow for stretch

Reticular
Short, fine, highly branched collagenous fibers
Term
Examples of CT Cell types
Definition
Examples of Cell types
Fibroblasts in cartilage – high tensile strength fibers

Chondroblasts in cartilage – gel type matrix

Osteoblasts in bone – calcium/ phosphorus -matrix

Hematopoietic - in bone marrow
leukocytes& erythrocytes

Adipocytes - fat storage vacules/no matrix
Term
2 TYPES OF CT PROPER:
Definition
loose and dense
Term
loose CT 3 subgroups
Definition
Areolar
Adipose
Reticular
Term
DENSE CT 3 types:
Definition
Dense regular
Dense irregular
Elastic
Term
CTP ADIPOSE Description:
Definition
Matrix as in areolar,
but very sparse; closely packed
adipocytes, or fat cells, have
nucleus pushed to the side by large
fat droplet.
Term
CTP ADIPOSE Function:
Definition
Provides reserve food
fuel; insulates against heat loss;
supports and protects organs.
Term
CTP RETICULAR description:
Definition
Network of reticular
fibers in a typical loose ground
substance; reticular cells lie on the
network.
Term
CTP RETICULAR function:
Definition
Fibers form a soft internal
skeleton (stroma) that supports other
cell types including white blood cells,
mast cells, and macrophages.
Term
CTP DENSE description:
Definition
Primarily parallel
collagen fibers; a few elastic fibers;
major cell type is the fibroblast.
Term
CTP DENSE: TENDONS AND LIGAMENTS
Definition
: Primarily parallel
collagen fibers; a few elastic fibers;
major cell type is the fibroblast.
Term
CTP: Dense irregular: Joint Capsules
Definition
: Primarily
irregularly arranged collagen
fibers; some elastic fibers;
major cell type is the fibroblast.
Term
CTP: Dense: Elastic
Definition
: Dense regular
connective tissue containing a high
proportion of elastic fibers.
Term
Three types of cartilage:
Definition
Hyaline cartilage
Elastic cartilage
Fibrocartilage
Term
Cartilage: Hyaline
Definition
Amorphous but firm
matrix; collagen fibers form an
imperceptible network; chondroblasts
produce the matrix and when mature
(chondrocytes) lie in lacunae.
covers the ends
of long bones in joint cavities; forms
costal cartilages of the ribs; cartilages
of the nose, trachea, and larynx.
Term
Cartilage: Elastic
Definition
Similar to hyaline
cartilage, but more elastic fibers
in matrix.
Supports the external
ear (pinna); epiglottis.
Term
Cartilage: Fibrocartilage
Definition
: Matrix similar to
but less firm than that in hyaline
cartilage; thick collagen fibers
predominate.
: Intervertebral discs;
pubic symphysis; discs of knee
joint.
Term
Osseous Tissue (BONE)
Definition
Hard, calcified
matrix containing many collagen
fibers; osteocytes lie in lacunae.
Very well vascularized.
Function: Bone supports and
protects (by enclosing);
provides levers for the muscles
to act on; stores calcium and
other minerals and fat; marrow
inside bones is the site for blood
cell formation (hematopoiesis).
Term
Skeletal Muscle Characteristics
Definition
long & cylindrical
Striated
Contractile units
Multi-nucleate
Voluntary control
Term
Cardiac Muscle - Characteristics
Definition
Branching
Striated
Intercalated discs
Uni-nucleate
Involuntary control
Term
Intercalated disc
Definition
an identifying feature of cardiac muscle. Cardiac muscle consists of single heart muscle cells (cardiomyocytes) which have to be connected by intercalated discs to work as a functional organ.
Term
Smooth Muscle - Characteristics
Definition
no visible striations
spindle shape
uni-nucleate
Involuntary
Term
Nervous Tissue - Characteristics
Definition
Highly irritable
Transmits electrical energy
RMP is essential!
long processes (sensory & effector)
Many support cells (neuroglia)
Term
Tissue Repair 2 types
Definition
regeneration
fibrosis
Term
Steps of tissue repair:
Definition
Inflammation
Organization and restored blood supply
Regeneration and fibrosis
Term
Inflammation:
Definition
Release of inflammatory chemicals
Dilation of blood vessels
Increase in vessel permeability
Clotting occurs

This stops the leakage of blood and holds the tissue edges together and isolates the injured area = infection barrier
Term
2. Organization and restored blood supply:
Definition
The blood clot is replaced with granulation tissue
Epithelium begins to regenerate (scab)
Fibroblasts produce collagen fibers with some elastin fibers to pull the edges together and to bridge the gap
Debris is phagocytized

Infection control is on going (local leukocytosis) – also granulation tissue resists bacteria chemically
Term
3. Regeneration and fibrosis
Definition
The scab finally detaches
Fibrous tissue matures; epithelium thickens and begins to resemble adjacent tissue
Results in a fully regenerated epithelium – may have underlying scar tissue depending upon the severity and depth of the wound.
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