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Integumentary System
skin
52
Anatomy
12th Grade
10/17/2012

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Cards

Term
Functions of the skin
Definition

Thermoregulation

Protection

Retardation

Excretion

Storage

Synthesis

Reservoir

Term
Retardation
Definition
holding back, outer layer of epidermis holds in water
Term
4 main cell types of Epidermis
Definition

Keratincytes

Melanocytes

Langerhans

Merkel

Term
the tissue in Epidermis is...
Definition
AVASCULAR
Term
Deepest layer of cells and what happens there
Definition
Stratum Basale - home to dividing cells
Term
Keratinization
Definition
the process by which epidermal cells die as they migrate up...they flatten out and become squamous shaped.
Term
Job of the Epidermis
Definition
Protects the underlying layers of skin
Term
Melanocytes
Definition
cells that produce pigamnet,  (deals with touch sensations?) ..don't know what notes mean
Term
Blisters
Definition
an area where fluid builds up
Term
Callus
Definition
areas of constant rubbing, cells stop sloughing here - builds up and becomes thick skin
Term
Insensible Perspiration
Definition
passive sweating (500 mL a day)
Term
Apoptosis
Definition
cellular death - genetically programmed death
Term
Layers of Epidermis bottom to top
Definition

Stratum basale

Stratum spinosum

Stratum granulosum

Stratum lucidum

Straum corneum

Term
Stratum basale
Definition

deepest layer, where Epidermal Stem Cells mature into Keratinocytes (EGF)

1-5 layers deep, ridges which form finger prints

Term
Stratum Spinosum
Definition

spinoum=thornlike

8-10 cells thick

Melanin is absorbed by phagocytosis/cytocrine secretion

Langerhan cells

Term
Stratum Granulosum
Definition

little grain

3-5 cells thick

cells begin to die here due to distance from vascular rich dermis

cells start to fill up with keratin

barrier againt light, heat, and bacteria

Term
Stratum Lucidum
Definition

thick skin

clear

3-5 layers of cells

only found in thick skin

support and protection

 

Term
Stratum Corneum
Definition

horny

25-30 layers of cells

keratinization complete

cells are flattened, dead and shed

dry to prevent bacterial growth

life span= 2-4 weeks

water resistant NOT water proof

Term
Dermis
Definition
connective tissue (dense irregular) as well as Collagen and Elastic Fibers and many other cells...Macrophages, Fibroblasts ad extensions of cells - nerves
Term
Subcutaneous
Definition

fat, AKA hypodermis

insulation/protection

adiposcytes

Term
Nails are made of?
Definition
keratin
Term
the lunula is where.........
Definition
new cells grow!
Term
The job of hair is to..
Definition
keep warm
Term
color is caused by what factors?
Definition

genetics

melanin from melanocytes

pigament - trichosiderin

Term

the Sebaceous Gland  is associated with what?

What does it do?

Definition

associated with hair follicles and secretes sebum which waterproofs and moisturizes hair shafts

 

also known as holocrine gland

Term
Sudoriferous
Definition

Sweat Glands

merocrine eccrine deals with ody temperature

or apocrine - temperature, stress, sexual arousal

Term
Ceruminous
Definition
modified sweat glands that secrete wax in the ear canal
Term
Mammary
Definition
Modified sweat gland that secretes milk;)
Term
Temperature Regulation
Definition

Proper temperature is vital, skin plays a major role with hypothalamus controlling it, active cells play a role (heart/skeletal muscles)

Heat is lost from skin radiation so body respnds to excessive heat by dilation of dermal blood vessels

excessive cooling by constricting dermal blood vessels - shivering

Term
Langerhan Cells
Definition
white blood cells
Term
Merkel Cells
Definition
connect with nerves
Term
papillary layer
Definition
consist of loose connective tissue contains capillaries and the sensory neurons supplying the surface of the skin
Term
reticular layer
Definition
consist of interwoven meshwork of dense irregular connective tissue
Term
skin turgor
Definition
(properties) the water content of thes skin also helps maintain its flexibilty and resilience
Term
keloid
Definition
thickened area of scar tissue
Term
germinative cell activity
Definition
prone to injury and skin infection when decreases
Term
5 key factors of aging
Definition

epidermis thins

langerhan cells decrease - Melanocyte activity decreases

Glandular activity decreases, skin gets dry

blood supply to dermis is reduced and sweat glands become less active..lose body heat

dermis becomes thinner and alastic fiber network decreases in size

Term
4 steps in Integumentary repair
Definition

1. Bleeding occurs at injury site and mast cells trigger inflammation

2. A scab forms, cells from Stratum germinative migrate into the wound to start growing new skin.  Phagocytes invade and clot forms

3. Fibroblasts begin to produce scar tissue and epidermis keeps growing

4. Scab has been shed and the epidermis is complete.  Fibroblasts continue to lay down scar tissue and shallow depression that marks the injury site will fill in.

Term
vitiligo
Definition
weird skin abnormalities, Michael Jackson
Term
   Terminal Hair
Definition

eyelashes, eyebrows, hair on head,

longer, heavily pigmented, much more coarse

Term
Vellus
Definition
peach fuzz
Term
medulla
Definition
holds pigament
Term
merocrine
Definition

most common sweat gland

end at pore

main function is thermoregulation

starts functioning shortly after birth

Term
Apocrine
Definition

mostly in armpit

starts to function at puberty

odorless but interacts with bacteria

Term
Healing of Wounds
Definition

Inflammation

blood vessels dilate and become more permeable

clots form scabs which are filled by fibroblasts then connective tissue is created

Term
abscess
Definition
accumulation of pus in an enclosed tissue space
Term
lysosomal enzymes
Definition
destroy injured cells and then attack surrounding tissues
Term
fibrosis
Definition
the permanent replacement of normal tissue by fibrous tissue 
Term
carcinoma
Definition

uncontrolled growth of abnormal cells arising in the squamous cells

caused by sun exposure

starts outside then goes deeper

Term
Melanoma
Definition

unrepairable DNA damage

most dangerous type of skin cancer

melanin protects deeper layers of skin

Too much sun can cause growths to become cancerous

Term
Basal Cell Carcinoma
Definition

Common Skin cancer

top layer of epidermis

grows slowly and is non fatal

occurs on skin exposed to sun a lot

 

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